Characterization of a family of high-molecular-weight plasminogen activators secreted by a lung tumor cell line

1991 ◽  
Vol 1078 (3) ◽  
pp. 360-368 ◽  
Author(s):  
Shashikumar R. Harvey ◽  
J. Randall Loftus ◽  
Edward L. Hurley ◽  
Mary E. Ross ◽  
Gabor Markus
Keyword(s):  
Molecular Weight ◽  
Tumor Cell ◽  
Cell Line ◽  
High Molecular Weight ◽  
Lung Tumor ◽  
Tumor Cell Line ◽  
Plasminogen Activators ◽  
Lung Tumor Cell

Identification and Characterization of a Novel hsc70-like Gene in the Human Lung Tumor Cell Line HS24

1997 ◽  
Vol 16 (3) ◽  
pp. 257-268 ◽  
Author(s):  
A.M. SCHULTE ◽  
S. FISCHER ◽  
G.E. SACHSE ◽  
S. HÄ"FNER ◽  
S. STELCK ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Human Lung ◽  
Lung Tumor ◽  
Tumor Cell Line ◽  
Human Lung Tumor ◽  
Identification And Characterization ◽  
Lung Tumor Cell

scholarly journals Establishment and characterization of a patient-derived circulating lung tumor cell line in vitro and in vivo

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Zujun Que ◽  
Bin Luo ◽  
Zhiyi Zhou ◽  
Changsheng Dong ◽  
Yi Jiang ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Lung Tumor ◽  
Tumor Cell Line ◽  
Lung Tumor Cell

scholarly journals Jaagsiekte Sheep Retrovirus Proviral Clone JSRVJS7, Derived from the JS7 Lung Tumor Cell Line, Induces Ovine Pulmonary Carcinoma and Is Integrated into the Surfactant Protein A Gene

2001 ◽  
Vol 75 (9) ◽  
pp. 4239-4246 ◽  
Author(s):  
James C. DeMartini ◽  
Jeanette V. Bishop ◽  
Thomas E. Allen ◽  
F. A. Jassim ◽  
J. Michael Sharp ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Lung Tumor ◽  
Protein A ◽  
Tumor Cell Line ◽  
Surfactant Protein ◽  
Surfactant Protein A ◽  
Jaagsiekte Sheep Retrovirus ◽  
Pulmonary Carcinoma ◽  
Lung Tumor Cell

ABSTRACT Ovine pulmonary carcinoma (OPC) is a contagious neoplasm of alveolar epithelial type II (ATII) or Clara cells caused by a type D/B chimeric retrovirus, jaagsiekte sheep retrovirus (JSRV). Here we report the isolation, sequencing, pathogenicity, and integration site of a JSRV provirus isolated from a sheep lung tumor cell line (JS7). The sequence of the virus was 93 to 99% identical to other JSRV isolates and contained all of the expected open reading frames. To produce virions and test its infectivity, the JS7 provirus (JSRVJS7) was cloned into a plasmid containing a cytomegalovirus promoter and transfected into 293T cells. After intratracheal inoculation with virions from concentrated supernatant fluid, JSRV-associated OPC lesions were found in one of four lambs, confirming that JSRVJS7 is pathogenic. In JS7-cell DNA, the viral genome was inserted in the protein-coding region for the surfactant protein A (SP-A) gene, which is highly expressed in ATII cells, in an orientation opposite to the direction of transcription of the SP-A gene. No significant transcription was detected from either the viral or the SP-A gene promoter in the JS7 cell line at passage level 170. The oncogenic significance of the JSRV proviral insertion involving the SP-A locus in the JS7 tumor cell line is unknown.

scholarly journals Accessing anti-human lung tumor cell line (A549) potential of newer 3,5-disubstituted pyrazoline analogs

2017 ◽  
Vol 10 (5) ◽  
pp. 624-630 ◽  
Author(s):  
Zhi-Hui Lu ◽  
Xi-Juan Gu ◽  
Ke-Zhi Shi ◽  
Xuan Li ◽  
Dian-Dian Chen ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Human Lung ◽  
Lung Tumor ◽  
Tumor Cell Line ◽  
Human Lung Tumor ◽  
Lung Tumor Cell

scholarly journals Long-term adaptation of the human lung tumor cell line A549 to increasing concentrations of hydrogen peroxide

Tumor Biology ◽  
2012 ◽  
Vol 33 (3) ◽  
pp. 739-748 ◽  
Author(s):  
Abdullah Onul ◽  
Kim M. Elseth ◽  
Humberto De Vitto ◽  
William A. Paradise ◽  
Benjamin J. Vesper ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Tumor Cell ◽  
Cell Line ◽  
Human Lung ◽  
Lung Tumor ◽  
Tumor Cell Line ◽  
Human Lung Tumor ◽  
Lung Tumor Cell

scholarly journals Secretion of antileucoprotease from a human lung tumor cell line

FEBS Letters ◽  
1987 ◽  
Vol 224 (1) ◽  
pp. 14-18 ◽  
Author(s):  
B. Appelhans ◽  
B. Ender ◽  
G. Sachse ◽  
T. Nikiforov ◽  
H. Appelhans ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Line ◽  
Human Lung ◽  
Lung Tumor ◽  
Tumor Cell Line ◽  
Human Lung Tumor ◽  
Lung Tumor Cell
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