Effects of prenatal exposure to benzodiazepine-related drugs on early development and adult social behaviour in swiss mice—III. Inverse agonists

1991 ◽  
Vol 22 (1) ◽  
pp. 53-60 ◽  
Author(s):  
Vibha Pankaj ◽  
Paul F. Brain
Keyword(s):  
Early Development ◽  
Prenatal Exposure ◽  
Social Behaviour ◽  
Inverse Agonists ◽  
Swiss Mice

GESELL TESTS ON AFRICAN CHILDREN

PEDIATRICS ◽  
1957 ◽  
Vol 20 (6) ◽  
pp. 1055-1065
Author(s):  
Marcelle Geber ◽  
R. F. A. Dean
Keyword(s):  
Early Development ◽  
Motor Development ◽  
Social Behaviour ◽  
Infants And Children ◽  
The Third ◽  
Potential Value ◽  
African Children ◽  
European Standards

The results of a series of Gesell tests on African infants and children are presented. The most remarkable finding was the precocity of the younger infants. The motor development was greatly in advance of that of European infants of the same age, but was not an isolated phenomenon; it was paralleled by advanced adaptivity, language and personal-social behaviour. The precocity was usually lost in the third year, but was retained by some children who had the advantages of a kinderganten. The results of the Gesell tests were confirmed by a study of newborn African infants, whose state of development was also precocious by European standards. The findings are discussed in relation to some details of the African environment, and especially to some local customs which may affect early development. Emphasis is placed on the potential value of finding means by which the early precocity could be maintained.

Ultrastructural Observations of Ovarian Ceroid Accumulation in Mice Exposed In Vitro to Diethylstilbestrol (DES)

1981 ◽  
Vol 39 ◽  
pp. 544-545
Author(s):  
R. Wordinger ◽  
G. Miller
Keyword(s):  
Light Microscopy ◽  
Prenatal Exposure ◽  
Corn Oil ◽  
Female Offspring ◽  
Swiss Mice ◽  
Estrogen Exposure ◽  
Vaginal Plug ◽  
Pregnant Mice

Genetial tract abnormalities in female offspring have been reported in mice following prenatal exposure to diethylsti1bes- trol (DES). Some of these abnormalities may be ovarian-dependent since most offspring are in a persistant estrogenic state even at 12-18 months of age. Accumulation of ovarian ceroid after long-term estrogen exposure has been described by light microscopy. This study was designed to examine the ultrastructure of ceroid accumulation in ovaries of mice exposed prenatally to DES.Virgin random bred Swiss mice 6-8 weeks old, were placed with individual males and examined daily for vaginal plugs. The presence of a vaginal plug was considered Day 0 of pregnancy. Pregnant mice were given a s.c. injection of DES (10μg/kg in 0.1.cc corn oil) or corn oil on Day 15 of gestation. All animals were allowed to give birth, and offspring were weaned at 4 weeks of age. Female offspring were housed in groups of 6 until 5 months of age and then sacrificed.

Ethanol and social behaviour in naive Swiss mice

1982 ◽  
Vol 8 (2) ◽  
pp. 204-207 ◽  
Author(s):  
Robert Smoothy ◽  
Nigel J. Bowden ◽  
Michael S. Berry
Keyword(s):  
Social Behaviour ◽  
Swiss Mice
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