N-methyl-d-aspartate receptor blockade impairs behavioural performance of rats in a reaction time task: New evidence for glutamatergic-dopaminergic interactions in the striatum

Neuroscience ◽  
1994 ◽  
Vol 61 (3) ◽  
pp. 521-531 ◽  
Author(s):  
C. Baunez ◽  
A. Nieoullon ◽  
M. Amalric
GeroPsych ◽  
2011 ◽  
Vol 24 (4) ◽  
pp. 169-176 ◽  
Author(s):  
Philippe Rast ◽  
Daniel Zimprich

In order to model within-person (WP) variance in a reaction time task, we applied a mixed location scale model using 335 participants from the second wave of the Zurich Longitudinal Study on Cognitive Aging. The age of the respondents and the performance in another reaction time task were used to explain individual differences in the WP variance. To account for larger variances due to slower reaction times, we also used the average of the predicted individual reaction time (RT) as a predictor for the WP variability. Here, the WP variability was a function of the mean. At the same time, older participants were more variable and those with better performance in another RT task were more consistent in their responses.


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