Isolation and characterization of the functional gene encoding bovine cytochrome c oxidase subunit IV

Gene ◽  
1995 ◽  
Vol 162 (2) ◽  
pp. 313-318 ◽  
Author(s):  
Nancy J. Bachman
Keyword(s):  
Cytochrome C ◽  
Cytochrome C Oxidase ◽  
Functional Gene ◽  
Gene Encoding ◽  
Oxidase Subunit ◽  
Isolation And Characterization

scholarly journals Isolation and characterization of a cDNA clone for bovine cytochrome c oxidase subunit IV.

1984 ◽  
Vol 81 (20) ◽  
pp. 6295-6299 ◽  
Author(s):  
M. I. Lomax ◽  
N. J. Bachman ◽  
M. S. Nasoff ◽  
M. H. Caruthers ◽  
L. I. Grossman
Keyword(s):  
Cytochrome C ◽  
Cytochrome C Oxidase ◽  
Cdna Clone ◽  
Oxidase Subunit ◽  
Isolation And Characterization

scholarly journals The cyclope Gene of Drosophila Encodes a Cytochrome c Oxidase Subunit VIc Homolog

Genetics ◽  
2001 ◽  
Vol 158 (4) ◽  
pp. 1629-1643
Author(s):  
Sébastien Szuplewski ◽  
Régine Terracol
Keyword(s):  
Cytochrome C ◽  
Cytochrome C Oxidase ◽  
Nuclear Dna ◽  
Essential Gene ◽  
Gene Encoding ◽  
Annotation Database ◽  
Amino Acid Peptide ◽  
Oxidase Subunit ◽  
The Central Nervous System

Abstract Cytochrome c oxidase is the terminal enzyme of the mitochondrial electron transfer chain. In eukaryotes, the enzyme is composed of 3 mitochondrial DNA-encoded subunits and 7–10 (in mammals) nuclear DNA-encoded subunits. This enzyme has been extensively studied in mammals and yeast but, in Drosophila, very little is known and no mutant has been described so far. Here we report the genetic and molecular characterization of mutations in cyclope (cype) and the cloning of the gene encoding a cytochrome c oxidase subunit VIc homolog. cype is an essential gene whose mutations are lethal and show pleiotropic phenotypes. The 77-amino acid peptide encoded by cype is 46% identical and 59% similar to the human subunit (75 amino acids). The transcripts are expressed maternally and throughout development in localized regions. They are found predominantly in the central nervous system of the embryo; in the central region of imaginal discs; in the germarium, follicular, and nurse cells of the ovary; and in testis. A search in the Genome Annotation Database of Drosophila revealed the absence of subunit VIIb and the presence of 9 putative nuclear cytochrome c oxidase subunits with high identity scores when compared to the 10 human subunits.

scholarly journals Isolation and characterization of the cDNAs encoding two isoforms of subunit CIX of bovine cytochrome c oxidase.

1990 ◽  
Vol 265 (5) ◽  
pp. 2677-2681
Author(s):  
R Lightowlers ◽  
G Ewart ◽  
R Aggeler ◽  
Y Z Zhang ◽  
L Calavetta ◽  
...  
Keyword(s):  
Cytochrome C ◽  
Cytochrome C Oxidase ◽  
Isolation And Characterization

Molecular Cloning and Characterization of the Rat Cytochrome c Oxidase Subunit Vb Gene

1994 ◽  
Vol 115 (2) ◽  
pp. 194-201 ◽  
Author(s):  
Haruki Hoshinaga ◽  
Naoki Amuro ◽  
Yoshitaka Goto ◽  
Taro Okazaki
Keyword(s):  
Cytochrome C ◽  
Molecular Cloning ◽  
Cytochrome C Oxidase ◽  
Oxidase Subunit
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