91174773 Prevention of bone loss by hormone replacement therapy is probably not due to stimulation of calcitonin secretion

Maturitas ◽  
1991 ◽  
Vol 14 (1) ◽  
pp. 84
Author(s):  
C.D. Fletcher ◽  
E. Farish ◽  
J. Leggate ◽  
D.M. Hart
1991 ◽  
Vol 124 (4) ◽  
pp. 353-356 ◽  
Author(s):  
C. D. Fletcher ◽  
E. Farish ◽  
J. Leggate ◽  
D. M. Hart

Abstract. Weekly fasting serum calcitonin levels and biochemical indices of bone metabolism were measured in 13 postmenopausal women being given hormone replacement therapy over a period of 8 weeks. All of the biochemical indices except urinary hydroxyproline creatinine ratios fell significatly, indicating that the treatments were effective in reducing bone turnover. Calcitonin levels fell significantly and, within the individual, levels were positively correlated with adjusted calcium levels. These findings do not support the theory that estrogen conserves bone by stimulating calcitonin secretion.


Sign in / Sign up

Export Citation Format

Share Document