scholarly journals Neurologic and neuropsychological morbidity following major surgery: comparison of coronary artery bypass and peripheral vascular surgery

1988 ◽  
Vol 8 (2) ◽  
pp. 210
Author(s):  
Daniel J. Reddy
1997 ◽  
Vol 10 (1-2) ◽  
pp. 1-6 ◽  
Author(s):  
J. E. Rohrer ◽  
M. S. Vaughan ◽  
R. P. Wenzel

The outcomes of cardiovascular care for individual patients are known to be better when treatment is provided in hospitals where the volume of such care is greater. We examined the impact of establishing safe volume thresholds on hospitals now performing such procedures in the state of Iowa by analysing the relationship between various volume thresholds and the number of hospitals that would continue to provide the service if the thresholds were enforced. Four procedures performed in hospitals in Iowa in 1990 were studied: coronary artery bypass graft surgery, vascular surgery, cardiac valve surgery, and cardiac catheterization. The analysis was conducted assuming current per capita procedure rates and repeated assuming reduced procedure rates. The study finds that the 12 hospitals now performing coronary artery bypass graft surgery in Iowa could be reduced to two, providers of vascular surgery could be reduced to as low as four from the current 33, the 10 providers of cardiac valve surgery might be reduced to one, and catheterization could be provided at two rather than 22 hospitals.


2007 ◽  
Vol 5 (3) ◽  
pp. 0-0
Author(s):  
Šarūnas Kinduris ◽  
Algimantas Budrikis ◽  
Juozas Sakalauskas ◽  
Algimantas Sasnauskas ◽  
Saulius Giedraitis

Šarūnas Kinduris1,2, Algimantas Budrikis1, Juozas Sakalauskas1, Algimantas Sasnauskas1, Saulius Giedraitis11 Kauno medicinos universiteto klinikų Širdies, krūtinės ir kraujagyslių chirurgijos klinika,Eivenių g. 2, LT-50009 Kaunas2 Kauno medicinos universiteto Biomedicininių tyrimų institutas,Eivenių g. 4, LT-50009 KaunasEl paštas: [email protected] Įvadas / tikslas Per pastaruosius kelis dešimtmečius pakartotinės operacijos (PO), nepaisant didelių pirminių skaičiaus svyravimų, sudaro nuo 2% iki 6% visų miokardo revaskulizacijos (MR) atvejų. Darbo tikslas – įvertinti ligonių, kuriems atliktos pakartotinės miokardo revaskulizacijos operacijos, kontingento pokyčius. Ligoniai ir metodai Atlikta retrospektyvioji duomenų analizė 80 ligonių, kuriems nuo 2001 m. sausio iki 2006 m. gruodžio Kauno medicinos universiteto Širdies, krūtinės ir kraujagyslių chirurgijos klinikoje atlikta pakartotinė MR operacija dirbtinės kraujo apytakos sąlygomis. Rezultatai Norėdami įvertinti operuojamo kontingento pokyčius, tiriamuosius ligonius suskirstėmė į keturias grupes: pakartotinė ir pirminė operacijos atliktos 2001–2004 metais – atitinkamai A (53 ligoniai) ir B (1775 ligoniai) grupės; pakartotinė ir pirminė operacijos atliktos 2005–2006 metais – atitinkamai C (27 ligoniai) ir D (1053 ligoniai) grupės. Tyrimo rezultatai parodė, kad pooperacinis A grupės ligonių mirštamumas 7,5% (4 ligoniai), B grupės – 3,2% (57 ligoniai), C grupės – 7,4% ir D grupės – 2,2%. Operacijų rizikai vertinti naudota kardiochirurgijoje priimta EuroSCORE sistema. Analizuojamaisiais laikotarpiais B ir D grupių ligonių tiek rizikos vertinimas balais (atitinkamai 6,3 ± 3,3 ir 6,6 ± 3,2), tiek prognozuojamu mirštamumu (9,0% ir 9,5%) nesiskyrė, o pakartotinių operacijų grupėse analogiški rodikliai sumažėjo (atitinkamai 9,98 ± 4,4 ir 8,3 ± 2,2 bei 23,9% ir 13,0%). Išvados Remiantis šio tyrimo rezultatais galima teigti, kad pakartotinė miokardo revaskulizacijos operacija per pastaruosius dvejus metus atliekama jaunesniems ligoniams, laikotarpis tarp operacijų ilgesnis. Tam, kad dažnesnė operacijos indikacija buvo jungčių nepratekamumas nei aterosklerozinio proceso progresavimas natyvinėse arterijose, galėjo turėti įtakos pastaruoju dešimtmečiu gerokai patobulėję konservatyvūs ir intervenciniai gydymo metodai kardiologijoje ir mažas kardiochirurgų atliekamų operacijų skaičius. Pagrindiniai žodžiai: pakartotinė operacija, miokardo revaskulizacija, jungčių pratekamumas Changing profile of patients undergoing redo coronary artery bypass operation Šarūnas Kinduris1,2, Algimantas Budrikis1, Juozas Sakalauskas1, Algimantas Sasnauskas1, Saulius Giedraitis11 Hospital of Kaunas University of Medicine, Department of Cardiothoracic and Vascular Surgery,Eivenių str. 2, LT-50009 Kaunas, Lithuania2 Kaunas University of Medicine, Institute for Biomedical Research,Eivenių str. 4, LT-50009 Kaunas, LithuaniaE-mail: [email protected] Background / objective Redo coronary artery bypass surgery (RECABG) operations represent about 2–6% of CABG operations. The aim of the study was to evaluate the profile of patients undergoing redo coronary artery bypass operations. Patients and methods Retrospective analysis of 80 patients operated on for RECABG in the Clinic of Cardiothoracic and Vascular Surgery of Kaunas University of Medicine was performed. Results To evaluate the profile of the patients, they were divided into four groups: redo and primary operations performed during 2001–2004 – groups A (53 patients) and B (1775) respectively; redo and primary operations performed in 2005–2006 – groups C (27 patients) and D (1053 patients) respectively. There was a 7.5% (4 patients) postoperative mortality in group A and 3.2% (57 patients) in group B. During 2005–2006, postoperative mortality was 7.4% and 2.2% respectively. The EuroSCORE system, well known in cardiac surgery, was used for operative risk assessment. Operative risk and predictive mortality in B and D groups during both evaluation periods was not significantly different (6.3 ± 3.3 and 6.6 ± 3.2 respectively and 9.0% and 9.5% respectively). On the other hand, evaluation of redo operations showed a decrease of these values with time (9.98 ± 4.4 and 8.3 ± 2.2; 23.9% and 13.0%, respectively). Conclusions Results of the study have shown that RECABG operations over the last two years have been performed for younger patients. Time interval between operations is longer and is associated with changes in the treatment of ischemic heart disease, but not with changes in the demographical situation in the country. Advanced conservative and invasive methods in cardiology during the last decade could influence the fact that an indication for RECABG became graft obstruction but not the progress of atherosclerosis in native coronary arteries. Key words: reoperation, coronary artery bypass, graft patency


2011 ◽  
Vol 164 (3) ◽  
pp. 413-419 ◽  
Author(s):  
Miguel Debono ◽  
Lorcan Sheppard ◽  
Sarah Irving ◽  
Philip Jackson ◽  
Jo Butterworth ◽  
...  

ObjectivePatients with cortisol deficiency poorly tolerate any systemic inflammatory response syndrome (SIRS), and may die if not treated with sufficient exogenous glucocorticoids. Controversy surrounds what constitutes a ‘normal’ adrenal response in critical illness. This study uses conventional tests for adrenal insufficiency to investigate cortisol status in patients undergoing elective coronary artery bypass surgery, a condition frequently associated with SIRS.DesignA prospective, observational study.MethodsThirty patients with impaired left ventricular function (ejection fraction >23% <50%) underwent basal ACTH measurement, and a short cosyntropin test (250 μg, i.v.) 1 week preoperatively, and at +4 h following induction of general anaesthesia. Preoperatively, a 30 min cortisol level post cosyntropin >550 nmol/l was taken as a normal response.ResultsPrior to surgery, all patients had a normal response to cosyntropin. Postoperatively, eight patients (26.7%) did not achieve stimulated cortisol levels >550 nmol/l and the mean peak cortisol postoperatively was lower (1048 vs 730 nmol/l; P<0.001). There was a significant rise in ACTH after surgery (21 vs 184 ng/l; P=0.007) and reduction in Δ-cortisol post cosyntropin (579 vs 229 nmol/l; P<0.001). There was no change in basal cortisol pre- and post-operatively (447 vs 501; P=0.4). All patients underwent routine, uneventful postoperative recovery.ConclusionUp to one quarter of patients with a normal cortisol status preoperatively demonstrated a raised ACTH and deficient cortisol response postoperatively. Despite these responses, all patients had uneventful outcomes. These data reinforce the need for caution when interpreting results of endocrine testing following major surgery or in the intensive care environment, and that prognostic value of these results may be of limited use.


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