scholarly journals In situ replacement of arterial prostheses infected with bacterial biofilms: Long-term follow-up

1993 ◽  
Vol 17 (6) ◽  
pp. 1124
Keyword(s):  
Bacterial Biofilms ◽  
Arterial Prostheses ◽  
Long Term Follow Up ◽  
In Situ Replacement

scholarly journals In situ replacement of arterial prosthesis infected by bacterial biofilms: Long-term follow-up

1994 ◽  
Vol 19 (2) ◽  
pp. 226-235 ◽  
Author(s):  
Jonathan B. Towne ◽  
Gary R. Seabrook ◽  
Dennis Bandyk ◽  
Julie A. Freischlag ◽  
Charles E. Edmiston
Keyword(s):  
Bacterial Biofilms ◽  
Arterial Prosthesis ◽  
Long Term Follow Up ◽  
In Situ Replacement

scholarly journals Diffuse PRAME Expression Is Highly Specific for Thin Melanomas in the Distinction from Severely Dysplastic Nevi but Does Not Distinguish Metastasizing from Non-Metastasizing Thin Melanomas

Cancers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 3864
Author(s):  
Maximilian Gassenmaier ◽  
Matthias Hahn ◽  
Gisela Metzler ◽  
Jürgen Bauer ◽  
Amir Sadegh Yazdi ◽  
...  
Keyword(s):  
Prognostic Significance ◽  
Diagnostic Interpretation ◽  
Dysplastic Nevi ◽  
Melanocytic Tumors ◽  
Invasive Component ◽  
Uncertain Significance ◽  
Long Term Follow Up

Background: PReferentially expressed Antigen in MElanoma (PRAME) immunohistochemistry is increasingly used as diagnostic adjunct in the evaluation of melanocytic tumors. The expression and prognostic significance of PRAME in melanomas ≤1.0 mm and its diagnostic utility in the distinction from severely dysplastic compound nevi (SDN) have not been studied. Methods: We investigated and compared the immunohistochemical PRAME expression in 70 matched thin metastasizing and non-metastasizing melanomas and 45 nevi from patients with long-term follow-up (35 SDN and 10 unequivocally benign compound nevi). Results: Diffuse PRAME staining in >75% of lesional epidermal and dermal melanocytes identified 58.6% of thin melanomas but did not distinguish metastasizing from non-metastasizing melanomas (p = 0.81). A superficial atypical melanocytic proliferation of uncertain significance, in which the final diagnostic interpretation favored a SDN was the only nevus with diffuse PRAME expression (1/45). Melanomas and SDN with PRAME immunoreactivity exhibited different staining patterns. Most melanomas (67.6%) showed uniform PRAME expression in the in situ and invasive component, whereas most SDN (81.0%) showed a decreasing gradient with depth. Conclusion: Diffuse intraepidermal and dermal PRAME staining is highly specific for melanomas in the distinction from SDN. PRAME expression is not a prognostic biomarker in melanomas ≤1.0 mm.

Complications of long-term ventilation tubes

2013 ◽  
Vol 127 (5) ◽  
pp. 509-510 ◽  
Author(s):  
H Mohammed ◽  
P Martinez-Devesa
Keyword(s):  
Ventilation Tube ◽  
Material Degradation ◽  
Long Term Follow Up ◽  
Ventilation Tubes ◽  
Chronic Inflammatory Reaction ◽  
Materials Used ◽  
Long Term Ventilation

AbstractObjective:To demonstrate that ventilation tubes can remain in situ much longer than expected, and that the materials used in the manufacturing of these tubes can degrade and cause complications. Long-term follow up and replacement of the tube is recommended.Method:Case report and review of the literature concerning the use of long-term ventilation tubes.Results:In the case reported, the ventilation tube was in place for 19 years, which resulted in chronic ear discharge. When it was removed, it was noted that the tube itself had degraded and had caused a chronic inflammatory reaction.Conclusion:We recommend that the long-term use of ventilation tubes is followed up and that the tube is replaced before material degradation takes place.

Penile Melanoma In Situ: Long Term Follow Up

Urology ◽  
2020 ◽  
Vol 141 ◽  
pp. e51-e52
Author(s):  
Kevin Krughoff ◽  
Amichai Kilchevksy ◽  
Wayne Stadelmann ◽  
Timothy Gorman ◽  
Ramiro Madden-Fuentes
Keyword(s):  
Melanoma In Situ ◽  
Long Term Follow Up

LONG-TERM FOLLOW-UP OF PATIENTS WITH CARCINOMA IN SITU OF THE URINARY BLADDER

1999 ◽  
pp. 116
Author(s):  
Roxann M. Neumann ◽  
Liang Cheng ◽  
John C. Cheville ◽  
Bradley C. Leibovich ◽  
Bruce E. Spotts ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Carcinoma In Situ ◽  
Long Term Follow Up

Laryngeal Dysplasia: Epidemiology and Treatment Outcome

1995 ◽  
Vol 104 (8) ◽  
pp. 596-602 ◽  
Author(s):  
Keith E. Blackwell ◽  
Thomas C. Calcaterra ◽  
Yao-Shi Fu
Keyword(s):  
Treatment Group ◽  
Carcinoma In Situ ◽  
Invasive Carcinoma ◽  
Endoscopic Therapy ◽  
Partial Laryngectomy ◽  
Severe Dysplasia ◽  
Long Term Follow Up

A retrospective analysis was undertaken of 65 patients with long-term follow-up for laryngeal squamous dysplasia. Based on the degree of dysplasia demonstrated on initial biopsy, 0 of 6 patients showing hyperkeratosis without dysplasia, 3 of 26 patients (12%) showing mild dysplasia, 5 of 15 patients (33%) showing moderate dysplasia, 4 of 9 patients (44%) showing severe dysplasia, and 1 of 9 patients (11%) showing carcinoma in situ eventually progressed to invasive carcinoma. An analysis was made of the impact of various treatment modalities in 33 patients demonstrating moderate dysplasia, severe dysplasia, or carcinoma in situ. Invasive carcinoma developed in 10 of 21 patients (48%) treated endoscopically and 0 of 12 patients treated by more aggressive therapy, including external beam radiotherapy, partial laryngectomy, or total laryngectomy. Of the patients in the endoscopic therapy group who developed invasive carcinoma, all were salvaged successfully. The overall rate of laryngeal preservation was 15 of 21 patients (71%) in the endoscopic treatment group and 11 of 12 patients (92%) in the aggressive treatment group. This difference is not statistically significant. We conclude that there is a moderately high rate of progression to invasive carcinoma in patients undergoing repeated endoscopic therapy for intraepithelial neoplasms of the larynx. However, with close, long-term follow-up, patients undergoing endoscopic therapy have an overall outcome similar to that in patients treated with partial laryngectomy or radiotherapy prior to developing invasive disease.

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