University of Wisconsin Solution and human saphenous vein graft preservation: preliminary anatomic report

1993 ◽  
Vol 7 (10) ◽  
pp. 548-552 ◽  
Author(s):  
E SANTOLI ◽  
D DIMATTIA ◽  
R BOLDORINI ◽  
A MINGOLI ◽  
A TOSONI ◽  
...  
2018 ◽  
Vol 39 (suppl_1) ◽  
Author(s):  
M S Ruiter ◽  
G Garoffolo ◽  
M Piola ◽  
M Agrifoglio ◽  
M Zanobini ◽  
...  

1992 ◽  
Vol 104 (2) ◽  
pp. 224-228 ◽  
Author(s):  
Valluvan Jeevanandam ◽  
Joseph S. Auteri ◽  
Juan A. Sanchez ◽  
Daphne Hsu ◽  
Charles Marboe ◽  
...  

2011 ◽  
Vol 666 (1-3) ◽  
pp. 150-157 ◽  
Author(s):  
Naciye Yaktubay Döndaş ◽  
Nehir Sucu ◽  
Banu Coşkun Yilmaz ◽  
Halil Mahir Kaplan ◽  
Murat Özeren ◽  
...  

2002 ◽  
Vol 21 (2) ◽  
pp. 212-217 ◽  
Author(s):  
W. Stooker ◽  
H.W.M. Niessen ◽  
W.R. Wildevuur ◽  
V.W.M. van Hinsbergh ◽  
J. Fritz ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-12
Author(s):  
Bulent Demir ◽  
Burak Onal ◽  
Sibel Ozyazgan ◽  
Esra Demir ◽  
Vedat Bakuy ◽  
...  

Objective. To study pitavastatin’s effects on nuclear factor-kappa B (NF-κB ) and adhesion molecules in human saphenous vein graft endothelial culture indicating its pleotropic properties. Materials and Method. Low-dose (0.1 μM/L) and high-dose (1μM/L) pitavastatin calcium were administered as a frontline therapy in human saphenous endothelial cell culture, followed by induction of inflammation by TNF-α and determination of mRNA level alterations of ICAM-1 and NF-κB genes of endothelial cells using the qRT-PCR method. Additionally, immunofluorescence method was used to show the expression of NF-κB and ICAM-1. Finally, LDH levels were determined by the ELISA method to quantify cytotoxicity. Results. ICAM-1 mRNA expression in the low-dose pitavastatin+TNF-α group was significantly higher than that in the TNF-α group and significantly lower than that in the high-dose pitavastatin+TNF-α group (for all comparisons, P = 0.001). The low-dose pitavastatin+TNF-α group had a similar NF-κB mRNA expression with TNF-α and high-dose pitavastatin+TNF-α groups. Conclusion. Pitavastatin increases ICAM-1 mRNA expression in saphenous vein endothelial cells. Furthermore, the effect of pitavastatin on adhesion molecules appears independent of NF-κB. Novel studies are needed in this field.


Sign in / Sign up

Export Citation Format

Share Document