Oocyte donation: recipient age, not etiology of ovarian failure, impacts implantation rate.

1996 ◽  
Vol 3 (2) ◽  
pp. 210A
Author(s):  
M MOOMJY
1994 ◽  
Vol 112 (1) ◽  
pp. 510-516 ◽  
Author(s):  
José Gonçalves Franco Júnior ◽  
Ricardo Luiz Razera Baruffi ◽  
Ana Lúcia Mauri ◽  
Cláudia Guilhermino Pertersen ◽  
Márcia Siste Campos ◽  
...  

A total of 7 cycles of embryo transfer by oocyte donation were performed on 5 patients with premature ovary failure (POF). All donors were under 35 of age and the recipients average age was 38.6 years. For synchronization between donor and recipient a semi programmed menstrual cycle was used by means of oral contraceptive followed by ovarian stimulation of donor with clomiphene citrate and human menopausal gonadotrophin. The recipients were easily adjusted to the donors by a flexible model of gradually increasing doses of estradiol valerianate. The average number of oocytes donated was 3.14 and average embryo cleavage rate was 80.2%. The average number of embryos transferred was 2.57. Embryo implantation rate was 22.2%. Clinical gestations occurred in 57.1% of the cycles. This series is probably the first one in Brazilian literature on oocyte donation as treatment for infertility in patients with premature ovarian failure.


2018 ◽  
Vol 26 (12) ◽  
pp. 1661-1665 ◽  
Author(s):  
Alexis K. Masbou ◽  
Jenna B. Friedenthal ◽  
David H. McCulloh ◽  
Caroline McCaffrey ◽  
M. Elizabeth Fino ◽  
...  

Two of the many milestone developments in the field of assisted reproduction have been oocyte donation and preimplantation genetic testing for aneuploidy (PGT-A). Because it has been demonstrated that even young women produce a meaningful proportion of aneuploid embryos, screening out such abnormalities could potentially increase the efficacy of donor egg (DE) cycles. In this retrospective cohort study, we investigated the effect of PGT-A on DE cycle outcomes, including implantation rate (IR), spontaneous abortion rate (SABR), and ongoing pregnancy/live birth rate. We used fresh and frozen donor cycles not using PGT-A as comparison groups; all cases involved single embryo transfer. Data analysis revealed that PGT-A did not improve pregnancy outcome metrics in DE cycles, although there was a trend toward decreasing the SABR. There was a significant increase in IR with fresh cycles outperforming all frozen cycles. Overall, these results suggest that the benefits of performing PGT-A on embryos derived from young DEs may be limited and that there is an effect of the freezing process on pregnancy outcomes. These findings may provide useful insights into the science and practice of PGT-A across all of its applications.


2011 ◽  
Vol 55 (4) ◽  
pp. 291-293 ◽  
Author(s):  
Bashir Ahmad Laway ◽  
Syed Tufail ◽  
Mir Iftikhar Bashir ◽  
Mohd Ashraf Ganie ◽  
Abdul Hamid Zargar

Premature ovarian failure has an overall prevalence of 0.3% to 0.9% in general population. If fertility is a concern, treatment usually consists of estrogen therapy as hormone replacement and oocyte donation. Spontaneous pregnancy in affected women is uncommon. We report a case of a 34-year old woman, who had premature ovarian failure and primary hypothyroidism, and conceived spontaneously eleven years after the development of premature ovarian failure and correction of hypothyroidism.


1987 ◽  
Vol 1 (1) ◽  
pp. 105-111 ◽  
Author(s):  
R. H. Asch ◽  
J. P. Balmaceda ◽  
T. Ord ◽  
C. Borrero ◽  
L. J. Rodriguez Rigau ◽  
...  

2008 ◽  
Vol 17 (1) ◽  
pp. 94-100 ◽  
Author(s):  
Lii-Shung Huang ◽  
Maw-Sheng Lee ◽  
En-Hui Cheng ◽  
Tsung-Hsien Lee ◽  
Chung-Hsien Liu ◽  
...  

1992 ◽  
Vol 4 (6) ◽  
pp. 681 ◽  
Author(s):  
Steireghem AC Van ◽  
G Pados ◽  
P Devroey ◽  
M Bonduelle ◽  
Assche E Van ◽  
...  

Oocyte donation is now a 'routine' treatment for infertility. Oocyte donation is mainly carried out in women with primary ovarian failure or premature menopause or in women in whom different regimens of ovarian stimulation prevent the development of ovarian follicles. In our Centres, oocyte donation is also offered to women or couples who prefer not to use their own gametes because of high recurrent risk of chromosomal or monogenic diseases. The resulting pregnancies in these women as well as in a series of women with gonadal dysgenesis due to X-chromosome aneuploidies are reported.


2007 ◽  
Vol 88 ◽  
pp. S262 ◽  
Author(s):  
K.M. Brennan ◽  
E. Levens ◽  
A. Huang ◽  
K. Richter ◽  
D. Hill ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document