Sweat Glands and Salivary Glands as Model System for the Characterization of Monoclonal Antibodies against Differentiation Antigens of the Human Mammary Gland

1984 ◽  
pp. 1009-1012 ◽  
Author(s):  
PH. HAGEMAN ◽  
J. VAN DEN TWEEL ◽  
J. HILGERS ◽  
J. HILKENS ◽  
H. PETERSE ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Mammary Gland ◽  
Salivary Glands ◽  
Model System ◽  
Sweat Glands ◽  
Differentiation Antigens ◽  
Human Mammary Gland

Production and characterization of monoclonal antibodies to guinea pig lymphoid differentiation antigens

1983 ◽  
Vol 63 (2) ◽  
pp. 247-261 ◽  
Author(s):  
Joe Chiba ◽  
Thomas M. Chused ◽  
William M. Leiserson ◽  
Stephen E. Zweig ◽  
Ethan M. Shevach
Keyword(s):  
Monoclonal Antibodies ◽  
Guinea Pig ◽  
Differentiation Antigens

Monoclonal antibodies to the human mammary gland

1982 ◽  
Vol 394 (3) ◽  
pp. 279-293 ◽  
Author(s):  
C. S. Foster ◽  
P. A. W. Edwards ◽  
E. A. Dinsdale ◽  
A. M. Neville
Keyword(s):  
Monoclonal Antibodies ◽  
Mammary Gland ◽  
Human Mammary Gland

scholarly journals Immunohistochemical Characterization of Mammary Squamous Cell Carcinoma of the Dog

2008 ◽  
Vol 20 (6) ◽  
pp. 766-773 ◽  
Author(s):  
Francesco Sassi ◽  
Giuseppe Sarli ◽  
Barbara Brunetti ◽  
Federico Morandi ◽  
Cinzia Benazzi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Mammary Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Mammary Tumors ◽  
Squamous Cell Carcinomas ◽  
Sweat Glands ◽  
Malignant Skin Tumors ◽  
Malignant Skin

Squamous cell carcinoma of the mammary gland is rare in both veterinary and human medicine. Whereas human metaplastic and squamous variants are known, the objectives of the current study were to ascertain the presence of such entities in canine mammary tumors and to distinguish them from other (epidermal, sweat gland) squamous tumors that may develop in the same area. A panel of antibodies (anticytokeratin [CK] 19, CK 14, CK 5/6, pancytokeratin, and vimentin) was used on 18 mammary gland malignancies with squamous features and 16 malignant skin tumors (11 squamous cell carcinomas of the skin and 5 sweat glands). Fifteen of the 18 mammary carcinomas were classified as metaplastic carcinomas, and the remaining 3 were classified as squamous cell carcinomas. The 2 most useful markers to establish the histogenesis of mammary tumors were pancytokeratin and CK 19. All other antibodies were equally expressed (CK 14 and 5/6) in all histotypes. The antibody panel discriminated primary epidermal squamous tumors (pancytokeratin positive and CK 19 negative) from gland-derived squamous neoplasms (pancytokeratin positive and CK 19 positive) but failed to distinguish primary mammary tumors from other squamous tumors of glandular origin.

Characterization of renal neoplasms with monoclonal antibodies to leukocyte differentiation antigens

Cancer ◽  
1986 ◽  
Vol 57 (2) ◽  
pp. 251-256 ◽  
Author(s):  
Michael J. Borowitz ◽  
Mark A. Weiss ◽  
Edward H. Bossen ◽  
Richard S. Metzgar
Keyword(s):  
Monoclonal Antibodies ◽  
Renal Neoplasms ◽  
Differentiation Antigens
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