<b>Objective:</b> To assess the prevalence of and
trends in complications among US adults with newly diagnosed diabetes.
<p><b>Research design
and methods:</b> We
included 1,486 nonpregnant adults (aged≥20
years) with newly diagnosed diabetes (diagnosed within the past 2 years)
from the 1988-1994 and 1999-2018
National Health and Nutrition Examination Survey. We estimated trends in albuminuria
(albumin-to-creatinine ratio≥30 mg/g), reduced estimated glomerular filtration
rate (eGFR<60 ml/min/1.73 m<sup>2</sup>), retinopathy (any retinal microaneurysms
or blot hemorrhages), and self-reported cardiovascular disease (history of
congestive heart failure, heart attack, or stroke).</p>
<p><b>Results: </b>From 1988-1994
to 2011-2018, there was a significant decrease in the prevalence of albuminuria
(38.9 to 18.7%, p-for-trend<0.001), but no change in the prevalence of
reduced eGFR (7.5 to 9.9%, p-for-trend=0.30), retinopathy (1988-1994 to
1999-2008 only; 13.2 to 12.1%, p-for-trend=0.86), or self-reported
cardiovascular disease (19.0 to 16.5%, p-for-trend=0.64). There were
improvements in glycemic, blood pressure, and lipid control in the population,
and these partially explained the decline in albuminuria. Complications were
more common at the time of diabetes diagnosis for adults who were older, lower
income, less educated, and obese.</p>
<p><b>Conclusion:</b> Over the past three decades, there
have been encouraging reductions in albuminuria and risk factor control in
adults with newly diagnosed diabetes. However, the overall burden of
complications around the time of diagnosis remains high.</p>
Retinal Microaneurysms Detection Using Gradient Vector Analysis and Class Imbalance Classification
