Thyroglossal Duct Cysts and Ectopic Thyroid Tissue

Thyroglossal duct cysts are typically benign and usually asymptomatic. Malignant transformation is uncommon. Intralaryngeal extension is rare and results in dysphonia or dyspnea. There is no literature nowadays reporting the thyroglossal duct cyst carcinoma combining the clinical features of intralaryngeal extension. The authors present a case of progressive hoarseness and midline neck mass for 2 years. The laryngoscope and computed tomography revealed a 6-cm thyroglossal duct cyst containing ectopic thyroid tissue with intralaryngeal extension and causing airway obstruction. Complete excision with Sistrunk operation revealed papillary thyroid carcinoma. The patient resumed normal phonation after the surgery. There was no evidence of tumor recurrence and no hoarseness or dyspnea at 6 months follow up. This is the first reported case of a huge thyroglossal duct cyst carcinoma with intralaryngeal extension causing airway compromise. Complete excision of tumor is essential and vital to the symptom relief. A thyroglossal duct cyst carcinoma with endolaryngeal involvement should be considered in the differential diagnosis when the case has a massive midline neck mass with ectopic thyroid tissue and develops dyspnea or hoarseness concurrently.

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Submandibular ectopic thyroid gland: an uncommon presentation

The Egyptian Journal of Otolaryngology ◽

10.1186/s43163-021-00124-7 ◽

2021 ◽

Vol 37 (1) ◽

Author(s):

Inès Riahi ◽

Rim Fradi ◽

Ibtissem Ben Nacef ◽

Ahlem Blel

Keyword(s):

Thyroid Gland ◽

Thyroid Tissue ◽

Ectopic Thyroid ◽

Lingual Thyroid ◽

Submandibular Region ◽

Case Presentation ◽

Thyroglossal Duct ◽

Common Presentation ◽

Ectopic Thyroid Tissue ◽

Uncommon Presentation

Abstract Background Ectopic thyroid is a developmental anomaly of the thyroid gland of embryological origin. Instead of having a pretracheal situation, thyroid tissue is elsewhere, most commonly in the median cervical line along the course of the thyroglossal duct. Lingual thyroid is the most common presentation. Ectopic thyroid tissue in the submandibular region has been rarely reported. Case presentation We report herein a case of a 65-year-old man admitted to our department with a complaint of a painless swelling in the left submandibular region. Conclusions Thyroid gland ectopia should be considered among the differential diagnoses of submandibular swelling. Ectopic thyroid tissue can present with the same pathology affecting the normal thyroid gland such as malignancy and hyperthyroidism.

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Scintigraphic Demonstration of Ectopic Thyroid Tissue in a Thyroglossal Duct Cyst in the Presence of a Normal Thyroid

Clinical Nuclear Medicine ◽

10.1097/rlu.0b013e31822920f5 ◽

2011 ◽

Vol 36 (12) ◽

pp. 1142-1143 ◽

Cited By ~ 1

Author(s):

Sampath Santhosh ◽

Bhagwant Rai Mittal ◽

Koramadai Karuppusamy Kamaleshwaran ◽

Rahul Parghane ◽

Anish Bhattacharya ◽

...

Keyword(s):

Thyroid Tissue ◽

Thyroglossal Duct Cyst ◽

Ectopic Thyroid ◽

Duct Cyst ◽

Thyroglossal Duct ◽

Normal Thyroid ◽

Ectopic Thyroid Tissue

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Usefulness of hybrid single.photon emission computed tomography/computed tomography in a case of ectopic thyroid tissue in the thyroglossal duct remnant

Indian Journal of Nuclear Medicine ◽

10.4103/ijnm.ijnm_43_20 ◽

2021 ◽

Vol 36 (1) ◽

pp. 97

Author(s):

Enrico Calandri ◽

Luca Filippi ◽

Francesco Alessandro ◽

Ilaria Aretano ◽

Mirco Pultrone

Keyword(s):

Computed Tomography ◽

Thyroid Tissue ◽

Ectopic Thyroid ◽

Emission Computed Tomography ◽

Thyroglossal Duct ◽

Ectopic Thyroid Tissue ◽

Emission Computed ◽

Thyroglossal Duct Remnant

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Ectopic Papillary Carcinoma in the Midline Neck Accompanied by a Benign Thyroid Gland

Case Reports in Otolaryngology ◽

10.1155/2019/9172942 ◽

2019 ◽

Vol 2019 ◽

pp. 1-3

Author(s):

Lauran Evans ◽

SeHoon Park ◽

Christie Elliott ◽

Courtney Garrett

Keyword(s):

Thyroid Gland ◽

Unusual Case ◽

Thyroid Tissue ◽

Thyroglossal Duct Cyst ◽

The Body ◽

Ectopic Thyroid ◽

Duct Cyst ◽

Thyroglossal Duct ◽

Ectopic Thyroid Tissue ◽

Benign Thyroid

Ectopic thyroid tissue can deposit anywhere in the body. There are several cases reporting papillary thyroid carcinoma (PTC) arising from ectopic tissues; however, these cases largely presented with primary PTC within the native thyroid gland as well. Alternatively, some cases report of PTC found solely in an ectopic thyroglossal duct cyst, but reports of isolated malignancy in other types of ectopic thyroid tissue with normal native tissue are sparse throughout the literature. Here, we present an unusual case of PTC in the midline anterior neck that does not appear to be consistent with a thyroglossal duct cyst, accompanied by a completely benign native thyroid gland, of which only few cases have been reported.

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17 Surgery for Ectopic Thyroid Tissue and Thyroglossal Duct Cyst

10.1055/b-0041-182792 ◽

2021 ◽

Keyword(s):

Thyroid Tissue ◽

Thyroglossal Duct Cyst ◽

Ectopic Thyroid ◽

Duct Cyst ◽

Thyroglossal Duct ◽

Ectopic Thyroid Tissue

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Recurrent Graves’ Disease in Thyroglossal Duct Following Total Thyroidectomy

Surgery Case Reports ◽

10.31487/j.jscr.2021.02.02 ◽

2021 ◽

pp. 1-3

Author(s):

John Petrie IV ◽

Arvind Manisundaram ◽

Irene Yu ◽

Steven Schwaitzberg

Keyword(s):

Total Thyroidectomy ◽

Surgical Resection ◽

Hormone Replacement ◽

Thyroid Tissue ◽

Neck Mass ◽

Ectopic Thyroid ◽

Graves Disease ◽

Thyroglossal Duct ◽

Ectopic Thyroid Tissue ◽

Thyroglossal Duct Remnant

Introduction: A 46-year-old female with a past medical history of Graves’ disease refractory to medical management, thus requiring total thyroidectomy presented to clinic for recurrence of her hyperthyroidism and an increasing midline neck mass two years after her index operation. Case Description: CT imaging of the neck mass revealed a locally extensive enhancing abnormality immediately anterior to the hyoid bone within the infrahyoid muscles measuring 1.4x.1.9x4.0 cm. This was consistent with an exceedingly rare proliferation of a thyroglossal duct remnant secondary to recurrence of the patient’s Graves’ disease. The patient was treated with surgical resection of the neck mass shown to be ectopic Graves’ activated thyroid tissue by pathology. The patient was restarted on thyroid hormone replacement therapy and has remained euthyroid to date following surgical resection. Conclusion: The incidence of this event is estimated to be approximately one per a million persons and thus is a rare occurrence in endocrinology. This case highlights the potential shortcomings of surgical management of Graves’ disease. Following surgical resection, the autoimmune status of the patient remains unchanged. Ectopic thyroid tissue can be found anywhere along the embryologic descent of the thyroid gland and as low as the mediastinum. Thus, patients treated with total thyroidectomy should still be monitored regularly for recurrence of Graves’ disease secondary to ectopic thyroid tissue.

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