Hashimoto's thyroiditis in a patient with ectopic thyroid tissue

2017 ◽  
Author(s):  
Nadia Khessairi ◽  
Ibtissem Oueslati ◽  
Ons Rjeb ◽  
Fatma Chaker ◽  
Meriem Yazidi ◽  
...  
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Thyroid Tissue ◽  
Ectopic Thyroid ◽  
Hashimoto's Thyroiditis ◽  
Ectopic Thyroid Tissue

Hashimoto’s thyroiditis in ectopic thyroid tissue: a diagnostic surprise

Cytopathology ◽  
2011 ◽  
Vol 23 (6) ◽  
pp. 419-421 ◽  
Author(s):  
P. Pandey ◽  
A. Dixit ◽  
S. Bedi ◽  
K. Kapoor ◽  
N. C. Mahajan
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Thyroid Tissue ◽  
Ectopic Thyroid ◽  
Hashimoto's Thyroiditis ◽  
Ectopic Thyroid Tissue

scholarly journals Developing anterior mediastinum mass after orthotopic thyroidectomy: a case report

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Rita Meira Soares Camelo ◽  
José Maria Barros
Keyword(s):  
Thyroid Gland ◽  
Total Thyroidectomy ◽  
Thyroid Tissue ◽  
Anterior Mediastinum ◽  
Ectopic Thyroid ◽  
Ectopic Thyroid Tissue ◽  
Ectopic Tissue ◽  
Thyroid Scan ◽  
Imaging Results ◽  
Adjacent Structures

Abstract Background Ectopic thyroid tissue is a rare embryological aberration described by the occurrence of thyroid tissue at a site other than in its normal pretracheal location. Depending on the time of the disruption during embryogenesis, ectopic thyroid may occur at several positions from the base of the tongue to the thyroglossal duct. Ectopic mediastinal thyroid tissue is normally asymptomatic, but particularly after orthotopic thyroidectomy, it might turn out to be symptomatic. Symptoms are normally due to compression of adjacent structures. Case presentation We present a case of a 66-year-old male submitted to a total thyroidectomy 3 years ago, due to multinodular goiter (pathological results revealed nodular hyperplasia and no evidence of malignancy), under thyroid replacement therapy. Over the last year, he developed hoarseness, choking sensation in the chest, and shortness of breath. Thyroid markers were unremarkable. He was submitted to neck and thoracic computed tomography, magnetic resonance imaging, and radionuclide thyroid scan. Imaging results identified an anterior mediastinum solid lesion. A radionuclide thyroid scan confirmed the diagnosis of ectopic thyroid tissue. The patient refused surgery. Conclusions Ectopic thyroid tissue can occur either as the only detectable thyroid gland tissue or in addition to a normotopic thyroid gland. After a total thyroidectomy, thyroid-stimulating hormone can promote a compensatory volume growth of previously asymptomatic ectopic tissue. This can be particularly diagnosis challenging since ectopic tissue can arise as an ambiguous space-occupying lesion.

scholarly journals Thyroglossal Duct Cyst Papillary Carcinoma With Airway Compromise

2021 ◽  
pp. 014556132110220
Author(s):  
Po-Kai Huang ◽  
Li-Chun Hsieh ◽  
Yi-Shing Leu
Keyword(s):  
Symptom Relief ◽  
Thyroid Tissue ◽  
Neck Mass ◽  
Thyroglossal Duct Cyst ◽  
Ectopic Thyroid ◽  
Airway Compromise ◽  
Duct Cyst ◽  
Complete Excision ◽  
Thyroglossal Duct ◽  
Ectopic Thyroid Tissue

Thyroglossal duct cysts are typically benign and usually asymptomatic. Malignant transformation is uncommon. Intralaryngeal extension is rare and results in dysphonia or dyspnea. There is no literature nowadays reporting the thyroglossal duct cyst carcinoma combining the clinical features of intralaryngeal extension. The authors present a case of progressive hoarseness and midline neck mass for 2 years. The laryngoscope and computed tomography revealed a 6-cm thyroglossal duct cyst containing ectopic thyroid tissue with intralaryngeal extension and causing airway obstruction. Complete excision with Sistrunk operation revealed papillary thyroid carcinoma. The patient resumed normal phonation after the surgery. There was no evidence of tumor recurrence and no hoarseness or dyspnea at 6 months follow up. This is the first reported case of a huge thyroglossal duct cyst carcinoma with intralaryngeal extension causing airway compromise. Complete excision of tumor is essential and vital to the symptom relief. A thyroglossal duct cyst carcinoma with endolaryngeal involvement should be considered in the differential diagnosis when the case has a massive midline neck mass with ectopic thyroid tissue and develops dyspnea or hoarseness concurrently.

scholarly journals Submandibular ectopic thyroid gland: an uncommon presentation

2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Inès Riahi ◽  
Rim Fradi ◽  
Ibtissem Ben Nacef ◽  
Ahlem Blel
Keyword(s):  
Thyroid Gland ◽  
Thyroid Tissue ◽  
Ectopic Thyroid ◽  
Lingual Thyroid ◽  
Submandibular Region ◽  
Case Presentation ◽  
Thyroglossal Duct ◽  
Common Presentation ◽  
Ectopic Thyroid Tissue ◽  
Uncommon Presentation

Abstract Background Ectopic thyroid is a developmental anomaly of the thyroid gland of embryological origin. Instead of having a pretracheal situation, thyroid tissue is elsewhere, most commonly in the median cervical line along the course of the thyroglossal duct. Lingual thyroid is the most common presentation. Ectopic thyroid tissue in the submandibular region has been rarely reported. Case presentation We report herein a case of a 65-year-old man admitted to our department with a complaint of a painless swelling in the left submandibular region. Conclusions Thyroid gland ectopia should be considered among the differential diagnoses of submandibular swelling. Ectopic thyroid tissue can present with the same pathology affecting the normal thyroid gland such as malignancy and hyperthyroidism.

scholarly journals Missed retrosternal ectopic thyroid tissue in a patient operated for multinodular goiter

2016 ◽  
Vol 32 (1) ◽  
pp. 67-70
Author(s):  
Ugur Kesici ◽  
Ozgur Koral ◽  
Savas Karyagar ◽  
Sevgi Kesici ◽  
Aysun Yilbas ◽  
...  
Keyword(s):  
Multinodular Goiter ◽  
Thyroid Tissue ◽  
Ectopic Thyroid ◽  
Ectopic Thyroid Tissue

scholarly journals Ectopic thyroid tissue presenting as an external auditory canal mass

2019 ◽  
Vol 5 (2) ◽  
pp. 476
Author(s):  
Nishikanta Verma ◽  
Samuel Devanesan Abishegam ◽  
Abdul Razak Bin Haji Ahmad
Keyword(s):  
Thyroid Gland ◽  
Thyroid Tissue ◽  
The Body ◽  
Ectopic Thyroid ◽  
Thyroid Function Tests ◽  
External Ear ◽  
Ear Canal ◽  
Developmental Defects ◽  
External Ear Canal ◽  
Ectopic Thyroid Tissue

<p class="abstract">An ectopic thyroid is a rare occurrence with a majority of ectopic thyroid tissue located in the lingual region or in the midline. The abnormal sites represent developmental defects in migration from the floor of the primitive foregut at the foramen caecum of the tongue to the final pre-tracheal position of the gland. A few cases of ectopic thyroid tissue have also been reported from sites seemingly unrelated to the normal development of the thyroid gland.  We report a case of ectopic thyroid in the external ear canal, which presented as a small reddish mass in the external ear canal. To the best of our knowledge, this is the first such reported case in literature and adds to the body of knowledge in such cases. Although such a finding is exceedingly rare, the authors recommend routine histopathology in all cases of polyps in the external canal and standard investigation for the status of the residual thyroid gland via isotope scans, ultrasonography or thyroid function tests.</p>

scholarly journals Submandibular ectopic thyroid tissue and concurrent thyroid hemiagenesis

2021 ◽  
Vol 6 (1) ◽  
pp. 91-95
Author(s):  
Marie-Louise Uhre Hansen ◽  
Thomas Vedtofte ◽  
Irene Wessel ◽  
Mikkel Kaltoft
Keyword(s):  
Thyroid Tissue ◽  
Ectopic Thyroid ◽  
Ectopic Thyroid Tissue ◽  
Thyroid Hemiagenesis

scholarly journals Proteomics and Organoid Culture Reveal the Underlying Pathogenesis of Hashimoto’s Thyroiditis

2021 ◽  
Vol 12 ◽  
Author(s):  
Hui Xiao ◽  
Jianqing Liang ◽  
Sunqiang Liu ◽  
Qiongyue Zhang ◽  
Famin Xie ◽  
...  
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Gene Expression Regulation ◽  
Cell Metabolism ◽  
Thyroid Tissue ◽  
Hashimoto's Thyroiditis ◽  
Spectrometric Analysis ◽  
Preclinical Model ◽  
Needle Puncture ◽  
Organoid Culture ◽  
Chemokine Ligand

Hashimoto’s thyroiditis (HT) is an autoimmune disease, and its incidence continues to rise. Although scientists have studied this disease for many years and discovered the potential effects of various proteins in it, the specific pathogenesis is still not fully comprehended. To understand HT and translate this knowledge to clinical applications, we took the mass spectrometric analysis on thyroid tissue fine-needle puncture from HT patients and healthy people in an attempt to make a further understanding of the pathogenesis of HT. A total of 44 proteins with differential expression were identified in HT patients, and these proteins play vital roles in cell adhesion, cell metabolism, and thyroxine synthesis. Combining patient clinical trial sample information, we further compared the transient changes of gene expression regulation in HT and papillary thyroid carcinoma (PTC) samples. More importantly, we developed patient-derived HT and PTC organoids as a promising new preclinical model to verify these potential markers. Our data revealed a marked characteristic of HT organoid in upregulating chemokines that include C-C motif chemokine ligand (CCL) 2 and CCL3, which play a key role in the pathogenesis of HT. Overall, our research has enriched everyone’s understanding of the pathogenesis of HT and provides a certain reference for the treatment of the disease.

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