Cryptogenic Stroke | ScienceGate

Innovative percutaneous procedures for stroke prevention have emerged in the last two decades. Transcatheter closure of the patent foramen ovale (PFO) is performed in patients who suffered a cryptogenic stroke or a transient ischaemic attach (TIA) in order to prevent recurrence of thromboembolic events. Percutaneous occlusion of the left atrial appendage (LAA) has been introduced to reduce stroke risk in patients with atrial fibrillation (AF). The role of PFO and LAA in the occurrence of cerebrovascular events and the interventional device-based therapies to occlude the PFO and LAA are discussed.

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ULTRASOUND CHARACTERISTICS OF NON-OBSTRUCTIVE CAROTID ATHEROSCLEROSIS IN CRYPTOGENIC STROKE IN YOUNG ADULTS

10.26226/morressier.58e389b2d462b802923851c3 ◽

2017 ◽

Author(s):

Raphael Buon

Keyword(s):

Young Adults ◽

Carotid Atherosclerosis ◽

Cryptogenic Stroke ◽

Stroke In Young Adults ◽

Stroke In Young

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Faculty Opinions recommendation of Closure or medical therapy for cryptogenic stroke with patent foramen ovale.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14267257.15779440 ◽

2012 ◽

Author(s):

Philippa Newfield

Keyword(s):

Medical Therapy ◽

Patent Foramen Ovale ◽

Cryptogenic Stroke ◽

Foramen Ovale

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Faculty Opinions recommendation of Cryptogenic stroke and underlying atrial fibrillation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718467600.793526299 ◽

2016 ◽

Author(s):

Gregory Lip ◽

Farhan Shahid

Keyword(s):

Atrial Fibrillation ◽

Cryptogenic Stroke

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Faculty Opinions recommendation of Cryptogenic stroke and underlying atrial fibrillation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718467600.793514205 ◽

2016 ◽

Author(s):

Scott Kasner

Keyword(s):

Atrial Fibrillation ◽

Cryptogenic Stroke

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Faculty Opinions recommendation of Predictors of finding occult atrial fibrillation after cryptogenic stroke.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725426956.793538009 ◽

2017 ◽

Author(s):

Jose Biller ◽

Michael Schneck

Keyword(s):

Atrial Fibrillation ◽

Cryptogenic Stroke

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Patent Foramen Ovale, the Role of Antiplatelet Therapy Alone or Anticoagulant Therapy Alone Versus Device Closure for Cryptogenic Stroke: A Review of the Literature and Current Recommendations

Cardiovascular & Hematological Agents in Medicinal Chemistry ◽

10.2174/1871525718666200203111641 ◽

2020 ◽

Vol 18 (2) ◽

pp. 135-150

Author(s):

Harsha S. Nagarajarao ◽

Chandra P. Ojha ◽

Archana Kedar ◽

Debabrata Mukherjee

Keyword(s):

Patent Foramen Ovale ◽

Cryptogenic Stroke ◽

Narrow Channel ◽

Paradoxical Embolism ◽

Current Evidence ◽

Foramen Ovale ◽

The Right ◽

The Relationship ◽

Current Guidelines

: Cryptogenic stroke and its relation to the Patent Foramen Ovale (PFO) is a long-debated topic. Recent clinical trials have unequivocally established the relationship between cryptogenic strokes and paradoxical embolism across the PFO. This slit-like communication exists in everyone before birth, but most often closes shortly after birth. PFO may persist as a narrow channel of communication between the right and left atria in approximately 25-27% of adults. : In this review, we examine the clinical relevance of the PFO with analysis of the latest trials evaluating catheter-based closure of PFO’s for cryptogenic stroke. We also review the current evidence examining the use of antiplatelet medications versus anticoagulants for stroke prevention in those patients with PFO who do not qualify for closure per current guidelines.

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