scholarly journals The Discovery of Marine Natural Products with Therapeutic Potential

Author(s):  
J.McConnell Oliver ◽  
E.Longley Ross ◽  
E.Koehn Frank
2021 ◽  
Vol 4 (3) ◽  
pp. 76-82
Author(s):  
Sofia Khanam ◽  
Aman Prakash

Recently there is an increase in the interest in the secondary or non-primary metabolites produced by the marine flora and fauna. It has become the center of attraction of chemists and pharmacologists in the previous decades. Stakeholders of the natural viewpoint emphasize that the examination of new and unusual organic molecules from marine organisms while the synthetic stakeholders' faiths in targeting these novel structures for the development of new analogs and new synthetic strategies and methodologies. The chemistry of marine organisms has changed dramatically in concern of investigating rationale. Analogous to the examination of terrestrial plants, many of the recent research and studies have concentrated on the potential application of marine extracted products in the treatment, curing of human diseases, and various other works. Marine products are the major components having biomedical-oriented natural products which can be used for various purposes. Marine natural products have enough potential to work prominently and also assisting in various kinds of human needs and works. In this review, we will be focusing on prominently their works, role in biomedical-related aspects.


Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
DA Colosimo ◽  
F Cai ◽  
Y Hu ◽  
MB Potts ◽  
MA White ◽  
...  

Author(s):  
K. F. Albizati ◽  
V. A. Martin ◽  
M. R. Agharahimi ◽  
D. A. Stolze

2018 ◽  
Author(s):  
Jonathan J. Mills ◽  
Kaylib R. Robinson ◽  
Troy E. Zehnder ◽  
Joshua G. Pierce

The lipoxazolidinone family of marine natural products, with an unusual 4-oxazolidinone heterocycle at their core, represents a new scaffold for antimicrobial discovery; however, questions regarding their mechanism of action and high lipophilicity have likely slowed follow-up studies. Herein, we report the first synthesis of lipoxazolidinone A, 15 structural analogs to explore its active pharmacophore, and initial resistance and mechanism of action studies. These results suggest that 4-oxazolidinones are valuable scaffolds for antimicrobial development and reveal simplified lead compounds for further optimization.


2016 ◽  
Vol 23 (4) ◽  
pp. 360-382 ◽  
Author(s):  
Mousa Alghazwi ◽  
Yen Qi Kan ◽  
Wei Zhang ◽  
Wei Ping Gai ◽  
Xiao-Xin Yan

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