scholarly journals Enhancing the immune response in the sea cucumber Apostichopus japonicus by addition of Chinese herbs Houttuynia cordata Thunb as a food supplement

2019 ◽  
Vol 4 (3) ◽  
pp. 114-121 ◽  
Author(s):  
Huifeng Dang ◽  
Teng Zhang ◽  
Fan Yi ◽  
Shigen Ye ◽  
Juan Liu ◽  
...  
Keyword(s):  
Immune Response ◽  
Sea Cucumber ◽  
Apostichopus Japonicus ◽  
Food Supplement ◽  
Chinese Herbs ◽  
Houttuynia Cordata ◽  
Houttuynia Cordata Thunb

Effects of potential probiotics on growth performance and immune response of the juvenile sea cucumber (Apostichopus japonicus)

2010 ◽  
Vol 34 (6) ◽  
pp. 775-783 ◽  
Author(s):  
Hui-hui ZHOU ◽  
Hong-ming MA ◽  
Wen-bing ZHANG ◽  
Wei XU ◽  
Zhi-guo LIUFU ◽  
...  
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Sea Cucumber ◽  
Apostichopus Japonicus

Immune response of sea cucumber Apostichopus japonicus coelomocytes to several immunostimulants in vitro

Aquaculture ◽  
2010 ◽  
Vol 306 (1-4) ◽  
pp. 49-56 ◽  
Author(s):  
Min Gu ◽  
Hongming Ma ◽  
Kangsen Mai ◽  
Wenbing Zhang ◽  
Qinghui Ai ◽  
...  
Keyword(s):  
Immune Response ◽  
Sea Cucumber ◽  
Apostichopus Japonicus

A feedback loop involving FREP and NF-κB regulates the immune response of sea cucumber Apostichopus japonicus

2019 ◽  
Vol 135 ◽  
pp. 113-118 ◽  
Author(s):  
Liting Jiang ◽  
Zhixin Wei ◽  
Yina Shao ◽  
Xuelin Zhao ◽  
Ming Guo ◽  
...  
Keyword(s):  
Immune Response ◽  
Feedback Loop ◽  
Sea Cucumber ◽  
Apostichopus Japonicus

Anti-Enterovirus 71 Activity Screening of Chinese Herbs with Anti-Infection and Inflammation Activities

2009 ◽  
Vol 37 (01) ◽  
pp. 143-158 ◽  
Author(s):  
Tzou-Yien Lin ◽  
Yi-Chun Liu ◽  
Jia-Rong Jheng ◽  
Hui-Ping Tsai ◽  
Jia-Tsrong Jan ◽  
...  
Keyword(s):  
Antiviral Activity ◽  
Enterovirus 71 ◽  
Vero Cells ◽  
Chinese Herbs ◽  
Plaque Reduction Assay ◽  
Houttuynia Cordata ◽  
Cytopathic Effects ◽  
Infection And Inflammation ◽  
Activity Screening ◽  
Houttuynia Cordata Thunb

Antipyretic and toxin-eliminating traditional Chinese herbs are believed to possess antiviral activity. In this study, we screened extracts of 22 herbs for activity against enterovirus 71 (EV71). We found that only extracts of Houttuynia cordata Thunb. could neutralize EV71-induced cytopathic effects in Vero cells. The 50% inhibitory concentration of H. cordata extract for EV71 was 125.92 ± 27.84 μg/ml. Antiviral screening of herb extracts was also conducted on 3 genotypes of EV71, coxsackievirus A16 and echovirus 9. H. cordata extract had the highest activity against genotype A of EV71. A plaque reduction assay showed that H. cordata extract significantly reduced plaque formation. Viral protein expression, viral RNA synthesis and virus-induced caspase 3 activation were inhibited in the presence of H. cordata extract, suggesting that it affected apoptotic processes in EV71-infected Vero cells by inhibiting viral replication. The antiviral activity of H. cordata extract was greater in cells pretreated with extract than those treated after infection. We conclude that H. cordata extract has antiviral activity, and it offers a potential to develop a new anti-EV71 agent.

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