Coupling of gas chromatography and electrospray ionization high resolution mass spectrometry for the analysis of anabolic steroids as trimethylsilyl derivatives in human urine

2017 ◽  
Vol 964 ◽  
pp. 123-133 ◽  
Author(s):  
Eunju Cha ◽  
Eun Sook Jeong ◽  
Sangwon Cha ◽  
Jaeick Lee
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
High Resolution ◽  
Electrospray Ionization ◽  
Human Urine ◽  
High Resolution Mass Spectrometry ◽  
Anabolic Steroids ◽  
High Resolution Mass ◽  
Trimethylsilyl Derivatives ◽  
Resolution Mass

Immunoadsorption to improve gas chromatography/high-resolution mass spectrometry of estradiol-17 beta in plasma.

1983 ◽  
Vol 29 (4) ◽  
pp. 677-680 ◽  
Author(s):  
S J Gaskell ◽  
B G Brownsey
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
High Resolution ◽  
High Resolution Mass Spectrometry ◽  
Trimethylsilyl Ether ◽  
Internal Standard ◽  
Selected Ion Monitoring ◽  
High Resolution Mass ◽  
Precise Quantification ◽  
Resolution Mass

Abstract We describe a new, highly selective procedure for the determination of estradiol-17 beta in plasma. Samples are extracted with a micro-cellulose-coupled antiserum to estradiol-17 beta. Conversion of the extracted steroid to the bis(trimethylsilyl) ether is followed by gas chromatography/high-resolution mass spectrometry with selected ion monitoring. Precise quantification is achieved through the use of [2H3]estradiol-17 beta as internal standard.

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