Association of long QT syndrome loci and cardiac events among patients treated with β-blockers

2004 ◽  
Vol 13 (12) ◽  
pp. 45
Author(s):  
S.G. Priori ◽  
C. Napolitano ◽  
P.J. Schwartz
EP Europace ◽  
2016 ◽  
Vol 18 (suppl_1) ◽  
pp. i85-i85
Author(s):  
Yitschak Biton ◽  
Ilan Goldenberg ◽  
Wojciech Zareba ◽  
Kutyifa Valentina ◽  
Arthur J. Moss

2003 ◽  
Vol 67 (12) ◽  
pp. 1007-1012 ◽  
Author(s):  
Masao Yoshinaga ◽  
Masami Nagashima ◽  
Toshimitsu Shibata ◽  
Ichiro Niimura ◽  
Mitsuo Kitada ◽  
...  

Circulation ◽  
1999 ◽  
Vol 100 (24) ◽  
pp. 2431-2436 ◽  
Author(s):  
Parvin C. Dorostkar ◽  
Michael Eldar ◽  
Bernard Belhassen ◽  
Melvin M. Scheinman

2020 ◽  
Vol 11 ◽  
Author(s):  
Lu Han ◽  
Fuxiang Liu ◽  
Qing Li ◽  
Tao Qing ◽  
Zhenyu Zhai ◽  
...  

Long QT syndrome (LQTS) is an arrhythmic heart disease caused by congenital genetic mutations, and results in increased occurrence rates of polymorphic ventricular tachyarrhythmias and sudden cardiac death (SCD). Clinical evidence from numerous previous studies suggested that beta blockers (BBs), including atenolol, propranolol, metoprolol, and nadolol, exhibit different efficacies for reducing the risk of cardiac events (CEs), such as syncope, arrest cardiac arrest (ACA), and SCD, in patients with LQTS. In this study, we identified relevant studies in MEDLINE, PubMed, embase, and Cochrane databases and performed a meta-analysis to assess the relationship between the rate of CEs and LQTS individuals with confounding variables, including different gender, age, and QTc intervals. Moreover, a network meta-analysis was not only established to evaluate the effectiveness of different BBs, but also to provide the ranked efficacies of BBs treatment for preventing the recurrence of CEs in LQT1 and LQT2 patients. In conclusion, nadolol was recommended as a relatively effective strategy for LQT2 in order to improve the prognosis of patients during a long follow-up period.


2017 ◽  
Vol 38 (suppl_1) ◽  
Author(s):  
P.G. Platonov ◽  
S. McNitt ◽  
B. Polonsky ◽  
S. Rosero ◽  
A.J. Moss ◽  
...  

2010 ◽  
Vol 55 (10) ◽  
pp. A130.E1215
Author(s):  
James A. Kim ◽  
Arthur J. Moss ◽  
Coeli M. Lopes ◽  
Scott McNitt ◽  
Jennifer L. Robinson ◽  
...  

2012 ◽  
Vol 76 (9) ◽  
pp. 2112-2118 ◽  
Author(s):  
Masateru Takigawa ◽  
Mihoko Kawamura ◽  
Takashi Noda ◽  
Yuko Yamada ◽  
Koji Miyamoto ◽  
...  

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