Long-term mortality of patients with acute myocardial infarction in the United States and Canada: Comparison of patients enrolled in Global Utilization of Streptokinase and t-PA for Occluded coronary arteries (GUSTO)-I

2005 ◽  
Vol 14 (1) ◽  
pp. 10
Author(s):  
P. Kaul ◽  
P.W. Armstrong ◽  
W.C. Chang
Keyword(s):  
United States ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Coronary Arteries ◽  
The United States ◽  
Long Term Mortality

scholarly journals Long-Term Mortality of Patients With Acute Myocardial Infarction in the United States and Canada

Circulation ◽  
2004 ◽  
Vol 110 (13) ◽  
pp. 1754-1760 ◽  
Author(s):  
Padma Kaul ◽  
Paul W. Armstrong ◽  
Wei-Ching Chang ◽  
C. David Naylor ◽  
Christopher B. Granger ◽  
...  
Keyword(s):  
United States ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
The United States ◽  
Long Term Mortality

scholarly journals Does Diabetes Mellitus Increase the Short- and Long-Term Mortality in Patients With Critical Acute Myocardial Infarction? Results From American MIMIC-III and Chinese CIN Cohorts

2021 ◽  
Vol 12 ◽  
Author(s):  
Shiqun Chen ◽  
Zhidong Huang ◽  
Liling Chen ◽  
Xiaoli Zhao ◽  
Yu Kang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Harmful Effect ◽  
The United States ◽  
Short And Long Term ◽  
The Impact ◽  
Mimic Iii ◽  
Long Term Mortality

BackgroundThe harmful effect of diabetes mellitus (DM) on mortality in patients with acute myocardial infarction (AMI) remains controversial. Furthermore, few studies focused on critical AMI patients. We aimed to address whether DM increases short- and long-term mortality in this specific population.MethodsWe analyzed AMI patients admitted into coronary care unit (CCU) with follow-up of ≥1 year from two cohorts (MIMIC-III, Medical Information Mart for Intensive Care III; CIN, Cardiorenal ImprovemeNt Registry) in the United States and China. Main outcome was mortality at 30-day and 1-year following hospitalization. Kaplan-Meier curves and Cox proportional hazards models were constructed to examine the impact of DM on mortality in critical AMI patients.Results1774 critical AMI patients (mean age 69.3 ± 14.3 years, 46.1% had DM) were included from MIMIC-III and 3380 from the CIN cohort (mean age 62.2 ± 12.2 years, 29.3% had DM). In both cohorts, DM group was older and more prevalent in cardio-renal dysfunction than non-DM group. Controlling for confounders, DM group has a significantly higher 30-day mortality (adjusted odds ratio (aOR) (95% CI): 2.71 (1.99-3.73) in MIMIC-III; aOR (95% CI): 9.89 (5.81-17.87) in CIN), and increased 1-year mortality (adjusted hazard ratio (aHR) (95% CI): 1.91 (1.56-2.35) in MIMIC-III; aHR (95% CI): 2.62(1.99-3.45) in CIN) than non-DM group.ConclusionsTaking into account cardio-renal function, critical AMI patients with DM have a higher 30-day mortality and 1-year mortality than non-DM group in both cohorts. Further studies on prevention and management strategies for DM are needed for this population.Clinical Trial Registrationclinicaltrials.gov, NCT04407936.

scholarly journals Role of diuretics on long-term mortality may differ in volume status in patients with acute myocardial infarction

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T Kawai ◽  
D Nakatani ◽  
T Yamada ◽  
T Watanabe ◽  
T Morita ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Propensity Score ◽  
Plasma Volume ◽  
Cox Regression ◽  
Volume Status ◽  
Increased Risk ◽  
Long Term Mortality

Abstract Background Diuretics has been reported to have a potential for an activation of the renin-angiotensin-aldosterone system and the sympathetic nervous system, leading to a possibility of poor clinical outcome in patients with cardiovascular disease. However, few data are available on clinical impact of diuretics on long-term outcome in patients with acute myocardial infarction (AMI) based on plasma volume status. Methods To address the issue, a total of 3,416 survived patients with AMI who were registered to a large database of the Osaka Acute Coronary Insufficiency Study (OACIS) were studied. Plasma volume status was assessed with the estimated plasma volume status (ePVS) that was calculated at discharge as follows: actual PV = (1 − hematocrit) × [a + (b × body weight)] (a=1530 in males and a=864 in females, b=41.0 in males and b=47.9 in females); ideal PV = c × body weight (c=39 in males and c=40 in females), and ePVS = [(actual PV − ideal PV)/ideal PV] × 100 (%). Multivariable Cox regression analysis and propensity score matching were performed to account for imbalances in covariates. The endpoint was all-cause of death (ACD) within 5 years. Results During a median follow-up period of 855±656 days, 193 patients had ACD. In whole population, there was no significant difference in long-term mortality risk between patients with and without diuretics in both multivariate cox regression model and propensity score matching population. When patients were divided into 2 groups according to ePVS with a median value of 4.2%, 46 and 147 patients had ACD in groups with low ePVS and high ePVS, respectively. Multivariate Cox analysis showed that use of diuretics was independently associated with an increased risk of ACD in low ePVS group, (HR: 2.63, 95% confidence interval [CI]: 1.22–5.63, p=0.01), but not in high ePVS group (HR: 0.70, 95% CI: 0.44–1.10, p=0.12). These observations were consistent in the propensity-score matched cohorts; the 5-year mortality rate was significantly higher in patients with diuretics than those without among low ePVS group (4.7% vs 1.7%, p=0.041), but not among high ePVS group (8.0% vs 10.3%, p=0.247). Conclusion Prescription of diuretics at discharge was associated with increased risk of 5-year mortality in patients with AMI without PV expansion, but not with PV expansion. The role of diuretics on long-term mortality may differ in plasma volume status. Therefore, prescription of diuretics after AMI may be considered based on plasma volume status. Funding Acknowledgement Type of funding source: None

scholarly journals LONG-TERM PROGNOSTIC FACTORS OF IN-HOSPITAL SURVIVORS WITH ACUTE MYOCARDIAL INFARCTION WITH NON-OBSTRUCTIVE CORONARY ARTERIES

2021 ◽  
Vol 77 (18) ◽  
pp. 79
Author(s):  
Seung-Jae Joo ◽  
Yeekyoung Ko ◽  
Jong Wook Beom ◽  
Ki Yung Boo ◽  
Jae-Geun Lee ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Prognostic Factors ◽  
Coronary Arteries

scholarly journals Long-term mortality following interhospital transfer for acute myocardial infarction

Heart ◽  
2015 ◽  
Vol 101 (13) ◽  
pp. 1032-1040 ◽  
Author(s):  
Isuru Ranasinghe ◽  
Federica Barzi ◽  
David Brieger ◽  
Martin Gallagher
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Interhospital Transfer ◽  
Long Term Mortality

scholarly journals On Long-Term Mortality Trends in the United States, 1850-1968

Demography ◽  
1973 ◽  
Vol 10 (3) ◽  
pp. 405 ◽  
Author(s):  
S. L. N. Rao
Keyword(s):  
United States ◽  
The United States ◽  
Mortality Trends ◽  
Long Term Mortality
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