Fabrication and characterization of poly(γ-glutamic acid)-graft-chondroitin sulfate/polycaprolactone porous scaffolds for cartilage tissue engineering

2009 ◽  
Vol 5 (6) ◽  
pp. 1937-1947 ◽  
Author(s):  
Kuo-Yung Chang ◽  
Li-Wei Cheng ◽  
Guan-Huei Ho ◽  
Yun-Peng Huang ◽  
Yu-Der Lee
2012 ◽  
Vol 101A (8) ◽  
pp. 2174-2180 ◽  
Author(s):  
Cheng-Hung Chou ◽  
Herng-Sheng Lee ◽  
Tiing Yee Siow ◽  
Ming-Huang Lin ◽  
Amit Kumar ◽  
...  

2008 ◽  
Vol 396-398 ◽  
pp. 707-710 ◽  
Author(s):  
Takuro Adegawa ◽  
Yoshimi Ohyabu ◽  
Toshimasa Uemura ◽  
Tomohiko Yoshioka ◽  
Kazuo Shinozaki ◽  
...  

Porous scaffolds, consisted of hydroxyapatite (HAp), chondroitinsulfate (ChS) and collagen, were prepared by freeze-drying technique. HAp/ChS composite particles were incorporated into a collagen matrix. Scanning electron microscope (SEM) observations showed that the porous scaffolds involved interconnected pores whose size was 80~200 µm in diameter. The HAp/ChS particles were homogeneously distributed in the collagen matrix. Surface area of the scaffolds was increased by the incorporation of the particles. Compression tests in phosphate buffer saline indicated that the porous scaffolds had elastic property and had larger compressive modulus than the pure collagen scaffold. The porous scaffolds obtained in this study could be useful for a cartilage tissue engineering.


Sign in / Sign up

Export Citation Format

Share Document