Case series: Hyperdense basilar artery identified on unenhanced head CT in three cases of pediatric basilar artery occlusion

2020 ◽  
Author(s):  
Jennifer K. Potter ◽  
Jonathan D. Clemente ◽  
Andrew W. Asimos
Keyword(s):  
Basilar Artery ◽  
Case Series ◽  
Artery Occlusion ◽  
Basilar Artery Occlusion ◽  
Head Ct

The Basilar Artery International Cooperation Study (BASICS)

2007 ◽  
Vol 2 (3) ◽  
pp. 220-223 ◽  
Author(s):  
Wouter J. Schonewille ◽  
Christine A. C. Wijman ◽  
Patrik Michel ◽  
Ale Algra ◽  
L. Jaap Kappelle
Keyword(s):  
Basilar Artery ◽  
Case Series ◽  
Case Fatality ◽  
Artery Occlusion ◽  
Basilar Artery Occlusion ◽  
Poor Clinical Outcome ◽  
Target Number ◽  
International Registry ◽  
Number Of Patients ◽  
Overall Mortality

Basilar artery occlusion is a rare cause of stroke with a high case fatality rate and an often poor clinical outcome among survivors. Our limited knowledge on the outcome in patients with basilar artery occlusion comes from small case series of selected patients. Study Aim The main purpose of the registry is to collect preliminary data that will help direct the design of a future clinical treatment trial. The target number of patients included is 500. Design BASICS is a prospective, observational, multi-center, international registry of consecutive patients presenting with a symptomatic and radiologically confirmed basilar artery occlusion. Study Outcomes From November 2002 until December 2006 data have been collected on 400 patients, from 42 centers in 12 countries. Most patients were treated with IA therapy (55%), followed by antithrombotics (29%) and IV thrombolysis (6%). The overall mortality was 45%.

Abstract T MP25: Recanalization of Acute Basilar Artery Occlusion Improves Mortality and Functional Outcome: A Meta-Analysis

Stroke ◽  
2014 ◽  
Vol 45 (suppl_1) ◽  
Author(s):  
Gyanendra Kumar ◽  
Andrei V Alexandrov
Keyword(s):  
Basilar Artery ◽  
Subgroup Analysis ◽  
Case Series ◽  
Artery Occlusion ◽  
Basilar Artery Occlusion ◽  
Cochrane Library ◽  
Mortality Data ◽  
Significant Heterogeneity ◽  
Poor Outcome ◽  
Iv Tpa

Background and purpose: Randomized trial data supporting/refuting recanalization are sparse in acute basilar artery occlusion (BAO) with only one small RCT in literature. There is a wealth of data in the form of observational case series spanning several decades. We sought to synthesize outcome and mortality estimates from the available studies on acute BAO. Methods: MEDLINE, EMBASE, The Cochrane Library, and clinicaltrials.gov were searched with keywords “acute ischemic stroke” and “basilar artery occlusion”. Heterogeneity was calculated using Cochran Q (Q>df; p<0.5- significant), I2 and tau2. Dersimonian and Laird random-effects model was used to synthesize data. Pooled estimates were expressed as odds ratio (OR) and 95% CI. MIX Pro 2.0 was used for all analyses. Results: Thirty-seven studies provided mortality data (n= 1784), while 35 provided poor outcome data (n = 1755). In mortality synthesis, heterogeneity was significant (Q = 49.18, p = 0.07). Figure 1 shows OR for mortality with recanalization. ARR was 42.3% and NNT = 2.4. Subgroup analysis, separating IV TPA and IA therapy, revealed comparable ORs but heterogeneity was significant. In synthesis of poor outcome heterogeneity was not significant. Figure 2 shows OR for poor outcome with recanalization. ARR=35.3% and NNT=2.8. Subgroup analysis between IV TPA and IA therapy revealed comparable pooled ORs but significant heterogeneity in synthesis for IV TPA. Conclusion: Recanalization reduces mortality and poor outcome in BAO by OR of 0.19 and 0.20. These data do not support the notion that IA/mechanical intervention is superior to IV tPA since this effect persists when data are analyzed in each of these subgroups.

Top of Basilar Artery Infarction: A Case Series from Sudan

2021 ◽  
Author(s):  
Mahmoud Hussien Salih Daoud ◽  
Ejlal Ahmed.E.Abushama ◽  
Abdallah.H Mahmmoud ◽  
Moh.Mah.Fadelallah Eljack ◽  
Khabab Abbashar Hussein ◽  
...  
Keyword(s):  
Basilar Artery ◽  
Clinical Presentation ◽  
Case Series ◽  
Supportive Therapy ◽  
Artery Occlusion ◽  
Posterior Circulation ◽  
Basilar Artery Occlusion ◽  
Death Time ◽  
The Brain ◽  
Time Of Intervention

Abstract The posterior circulation represents 20% of blood supply of the brain and its occlusion commonly by embolism cause brainstem, cerebellar and lower cerebral infarction. The clinical presentation varies from mild innocent symptoms leading to sever neurological deficit or death. Time of intervention is vital commonly with antithrombatic drugs or through intervention. Here, we report two Sudanese patients who had a complicated medical sequence over months ended as top of basilar artery occlusion received anticoagulants and supportive therapy according to their condition showed a variable recovery over weeks.

Endovascular Treatment for Acute Basilar Artery Occlusion: A Nationwide Prospective Registry

2019 ◽  
Author(s):  
Wenjie Zi ◽  
Zhongming Qiu ◽  
Deping Wu ◽  
Fengli Li ◽  
Hansheng Liu ◽  
...  
Keyword(s):  
Endovascular Treatment ◽  
Basilar Artery ◽  
Artery Occlusion ◽  
Basilar Artery Occlusion

Late recanalization of basilar artery occlusion in a previously healthy 17-month-old child

2017 ◽  
pp. bcr-2017-013277
Author(s):  
D Andrew Wilkinson ◽  
Aditya S Pandey ◽  
Hugh J Garton ◽  
Luis Savastano ◽  
Julius Griauzde ◽  
...  
Keyword(s):  
Basilar Artery ◽  
Artery Occlusion ◽  
Basilar Artery Occlusion

Isolated basilar artery occlusion by parietal dissection after severe chest and minor head trauma

1998 ◽  
Vol 16 (6) ◽  
pp. 614-616 ◽  
Author(s):  
Massimo Gallerani ◽  
Vanni Veronesi ◽  
Stefano Ceruti ◽  
Giorgio Mantovani ◽  
Reza Ghadirpour
Keyword(s):  
Head Trauma ◽  
Basilar Artery ◽  
Artery Occlusion ◽  
Basilar Artery Occlusion ◽  
Minor Head Trauma

scholarly journals Predictors of Good Outcome After Stent-Retriever Thrombectomy in Acute Basilar Artery Occlusion

Stroke ◽  
2015 ◽  
Vol 46 (10) ◽  
pp. 2972-2975 ◽  
Author(s):  
Woong Yoon ◽  
Seul Kee Kim ◽  
Tae Wook Heo ◽  
Byung Hyun Baek ◽  
Yun Young Lee ◽  
...  
Keyword(s):  
Basilar Artery ◽  
Artery Occlusion ◽  
Stent Retriever ◽  
Basilar Artery Occlusion ◽  
Good Outcome

Bridging versus direct endovascular therapy in basilar artery occlusion

2021 ◽  
pp. jnnp-2020-325328
Author(s):  
Sergio Nappini ◽  
Francesco Arba ◽  
Giovanni Pracucci ◽  
Valentina Saia ◽  
Danilo Caimano ◽  
...  
Keyword(s):  
Ischaemic Stroke ◽  
Functional Outcome ◽  
Basilar Artery ◽  
Endovascular Therapy ◽  
Recombinant Tissue Plasminogen Activator ◽  
Artery Occlusion ◽  
Lower Mortality ◽  
Basilar Artery Occlusion ◽  
Bridging Therapy ◽  
Procedural Complications

BackgroundWe evaluated safety and efficacy of intravenous recombinant tissue Plasminogen Activator plus endovascular (bridging) therapy compared with direct endovascular therapy in patients with ischaemic stroke due to basilar artery occlusion (BAO).MethodsFrom a national prospective registry of endovascular therapy in acute ischaemic stroke, we selected patients with BAO. We compared bridging and direct endovascular therapy evaluating vessel recanalisation, haemorrhagic transformation at 24–36 hours; procedural complications; and functional outcome at 3 months according to the modified Rankin Scale. We ran logistic and ordinal regression models adjusting for age, sex, National Institutes of Health Stroke Scale (NIHSS), onset-to-groin-puncture time.ResultsWe included 464 patients, mean(±SD) age 67.7 (±13.3) years, 279 (63%) males, median (IQR) NIHSS=18 (10–30); 166 (35%) received bridging and 298 (65%) direct endovascular therapy. Recanalisation rates and symptomatic intracerebral haemorrhage were similar in both groups (83% and 3%, respectively), whereas distal embolisation was more frequent in patients treated with direct endovascular therapy (9% vs 3%; p=0.009). In the whole population, there was no difference between bridging and direct endovascular therapy regarding functional outcome at 3 months (OR=0.79; 95% CI=0.55 to 1.13). However, in patients with onset-to-groin-puncture time ≤6 hours, bridging therapy was associated with lower mortality (OR=0.53; 95% CI=0.30 to 0.97) and a shift towards better functional outcome in ordinal analysis (OR=0.65; 95% CI=0.42 to 0.98).ConclusionsIn ischaemic stroke due to BAO, when endovascular therapy is initiated within 6 hours from symptoms onset, bridging therapy resulted in lower mortality and better functional outcome compared with direct endovascular therapy.

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