Empowerment of Family in Early Detection of Total Growth at Puskesmas Karangrejo Metro

The target number of children in early detection of child development and development in the working area of ??Puskesmas Karangrejo is 1,037 children, with details of 133 infants from 0 - 11 months and 904 children aged 12 - 72 months. Of these, the coverage for early detection until February 2020 is still low, namely at 6.7%. The purpose of the Community Service is to empower families in conducting early detection of toddler growth and development in the Karangrejo Health Center area. The method of activity is health education and empowerment of “active participation” of mothers toddler in stimulating and detecting the growth and development of their children. The result of mentoring was that there was progress in the developmental ability of 1 child who had not been able to walk at the age of 19 months, showing an increase in walking ability after 2 weeks of assistance. There was an increase in the knowledge of mothers / families about growth and development by 12.68 points. There was an increase in the frequency of implementing stimulation for child growth and development by mothers of under-five from 88.2% of mothers who had stimulated to 98.6% after mentoring. Continuity of family empowerment is needed regarding early detection of growth and development and not only involving mothers / families but also involving cadres.

Establishment of A Reproductive Health Care Carader in Integrated Service Post (Posyandu) Youth Village Penyengat Olak Muaro Jambi District

At the posyandu for youth, the IEC includes providing information about adolescent reproductive organs, puberty, the process of pregnancy, menstruation, family planning, sexually transmitted diseases, gender and maturity of marriage age. HIV / AIDS includes providing information about transmission, prevention and symptoms. Based on data from the Health Office of Muaro Jambi Regency, in the area of ??Puskesmas Penyengat Olak, the target number of adolescents aged 10-18 years is 1,959 males and 1,903 females. This large number is an opportunity to form a youth posyandu. Community service activities will be carried out in Penyengat Olak Village, Muaro Jambi Regency. This community service aims to increase the capacity of youth as cadres of the village post at Penyengat Olak district. Muaro Jambi. Target adolescents aged 10-18 years who are in the area of ??olak stinger health centers. There are activities in the form of advocacy to puskesmas and the community in establishing youth Posyandu, recruiting cadres and holding youth Posyandu cadres training, implementing youth Posyandu formation in stinging olak villages. The output of community service activities is the formation of cadres to care for reproductive health in pilot youth Posyandu for the work area of ??the Pengegat Olak Community Health Center in Muaro Jambi Regency. olak stinger. Through this training activity it is very important to increase the coverage of adolescent reproductive health services and it is hoped that the support of the puskesmas and village officials is expected.

Edukasi Kesehatan Reproduksi Remaja Di Karangtaruna Pendowohardjo

Adolescence is the initial period of maturity of the reproductive organs in humans or the so-calledpuberty. Based on previous preliminary studies, adolescents prefer sources of reproductive health informationobtained from peers and parents, but if this is not given an explanation from health workers directly it will causedifferent perceptions from each teenager which can cause gaps. Based on the preliminary study, researchers areinterested in doing community service with the title "Adolescent Reproductive Health Education in KarangtarunaPendowohardjo". The purpose of this research is to increase the knowledge of adolescents about the importanceof reproductive health from a physical and psychological perspective. Adolescent Reproductive Health EducationActivities at Karangtaruna Pendowohardjo were carried out using counseling and demonstration methods, themedia used using teaching aids. The target audience in this community service is Youth, especially YouthOrganizations in Pendowohardjo Sewon Bantul with a target number of 48 Youth Youth Organizations. The resultsof this research are that adolescents gain knowledge and skills regarding Reproductive Health through counselingand demonstrations.

Virtual World Café Method for Identifying Mental Health Research Priorities: Methodological Case Study

People with lived experience of mental health problems as both consumers and carers can bring significant expertise to the research process. However, the methods used to gather this information and their subsequent results can vary markedly. This paper describes the methods for two virtual World Cafés held to gather data on consumer and carer priorities for mental health research. Several methodological processes and challenges arose during data collection, including the achieved recruitment for each group (n = 4, n = 7) falling significantly short of the target number of 20 participants per group. This led to departures from planned methods (i.e., the use of a single ‘room’, rather than multiple breakout rooms). Despite this, the participants in the virtual World Cafés were able to generate over 200 ideas for research priorities, but not identify agreed-upon priorities. Virtual World Cafés can quickly generate a significant volume of data; however, they may not be as effective at generating consensus.

Smad4 controls proliferation of interstitial cells in the neonatal kidney

Expansion of interstitial cells in the adult kidney is a hallmark of chronic disease, whereas their proliferation during fetal development is necessary for organ formation. An intriguing difference between adult and neonatal kidneys is that the neonatal kidney has the capacity to control interstitial cell proliferation when the target number has been reached. In this study, we define the consequences of inactivating the TGFβ/Smad response in the interstitial cell lineage. We find that pathway inactivation through loss of Smad4 leads to over-proliferation of interstitial cells regionally in the kidney medulla. Analysis of markers for BMP and TGFβ pathway activation reveals that loss of Smad4 primarily reduces TGFβ signaling in the interstitium. While TGFβ signaling is reduced in these cells, marker analysis shows that Wnt/β-catenin signaling is increased. Our analysis supports a model in which Wnt/β-catenin mediated proliferation is attenuated by TGFβ/Smad to ensure that proliferation ceases when the target number of interstitial cells has been reached in the neonatal medulla.

Early experience with an opt-in research register - Scottish Health Research Register (SHARE): a multi-method evaluation of participant recruitment performance

Background Recruiting participants to a clinical study is a resource-intensive process with a high failure rate. The Scottish Health Research Register (SHARE) provides recruitment support service which helps researchers recruit participants by searching patients’ Electronic Health Records (EHRs). The current study aims to evaluate the performance of SHARE in participant recruitment. Methods Recruitment projects eligible for evaluation were those that were conducted for clinical trials or observational studies and finished before 2020. For analysis of recruitment data, projects with incomplete data were excluded. For each project we calculated, from SHARE records, 1) the fraction of the participants recruited through SHARE as a percentage of the number requested by researchers (percentage fulfilled), 2) the percentage of the potential candidates provided by SHARE to researchers that were actually recruited (percentage provided and recruited), 3) the percentage of the participants recruited through SHARE of all the potentially eligible candidates identified by searching registrants’ EHRs (percentage identified and recruited). Research teams of the eligible projects were invited to participate in an anonymised online survey. Two metrics were derived from research teams’ responses, including a) the fraction of the recruited over the study target number of participants (percentage fulfilled), and b) the percentage of the participants recruited through SHARE among the candidates received from SHARE (percentage provided and recruited). Results Forty-four projects were eligible for inclusion. Recruitment data for 24 projects were available (20 excluded because of missingness or incompleteness). Survey invites were sent to all the eligible research teams and received 12 responses. Analysis of recruitment data shows the overall percentage fulfilled was 34.2% (interquartile 13.3–45.1%), the percentage provided and recruited 29.3% (interquartile 20.6–52.4%) and percentage identified and recruited 4.9% (interquartile 2.6–10.2%). Based on the data reported by researchers, percentage fulfilled was 31.7% (interquartile 5.8–59.6%) and percentage provided and recruited was 20.2% (interquartile 8.2–31.0%). Conclusions SHARE may be a valuable resource for recruiting participants for some clinical studies. Potential improvements are to expand the registrant base and to incorporate more data generated during patients’ different health care encounters into the candidate-searching step.

Penerapan Strategi Sosialisasi Preventif Covid -19 dan Optimalisasi Keuangan Keluarga pada saat Kondisi New Normal

Kelurahan Putat Jaya adalah salah satu kelurahan dengan jumlah penduduk sebanyak 2.300 Jiwa dengan 9 RT dan Lebih dari 680 Kepala Keluarga. Jumlah kasus positif Covid 19 pada tanggal 15 Juli 2020 sebanyak 9 orang Positif dan 1 Orang Meninggal, 22 orang ODP dan dinyatakan sembuhsejumlah 9 orang. Untuk di Kelurahan Putat Jaya ada permasalahan untuk sosialisasi didalam preventif terhadap pencegahan virus covid 19. Para penduduknya belum mengetahui preventif pencegahan covid 19 , cara penularannya dan penanganannya bila terkena Covid 19. Jumlah sasaran warga yang mengikuti sosialisasi adalah 680 kepala keluarga yang terdiri dari 9 RT. Kegiatan berlangsung mulai bulan juli 2020 sampai dengan november 2020. Metode penelitian menggunakan metode partisipatif. Metode pelaksanaan terdiri dari 4 tahap : (1) adalah memberikan peralatan pendukung preventive Covid 19, (2) sosialisasi melalui radio streaming fikom Universitas Ciputra dengan melibatkan tim medis, (3) mengadakan Webinar Pelatihan Managemen keuangan keluarga dan digital marketing di era New Normal, (4) publikasi kegiatan abdimas via radio steraming vikom dan jurnal abdimas. Hasil pelaksanaan kegiatan ini adalah memberikan kontribusi preventive pencegahan penularan covid 19 bagi warga RW 7 berupa penyediaan peralatan dan sosialisasi penggunaan peralatan, memberikan ilmu didalam menghadapi masa new normal khususnya didalam mengatur keuangan keluarga dan digital marketing kepada warga RW 7 serta meningkatkan kemampuan Satgas Covid 19. Kata Kunci: digital marketing; keuangan keluarga; kampung tangguh ; preventive Covid 19 ; radio streaming . Implementation of Covid – 19 Preventive Socialization Strategies and Optimization of Family Finances during New Normal ConditionsABSTRACT Putat Jaya Village is one of the villages with a population of 2,300 people with 9 RTs and more than 680 families. The number of positive cases of Covid 19 on July 15, 2020 was 9 positive people and 1 person died, 22 people were ODP and 9 people were declared cured. For the Putat Jaya Village, there are problems for socialization in prevention of the covid 19 virus prevention. The residents do not know the preventive measures against covid 19, how to transmit it and how to handle it when exposed to Covid 19. The target number of residents who participated in the socialization was 680 families consisting of 9 RT . The activity takes place from July 2020 to November 2020. The research method uses participatory methods .The implementation method consists of 4 stages: (1) is to provide Covid 19 preventive support equipment, (2) socialization via radio streaming fikom University of Ciputra involving the medical team, (3) holding a Training Webinar Family financial management and digital marketing in the New Normal era, (4) publication of abdimas activities via radio broadcasting vikom and abdimas journal. The results of the implementation of this activity are to provide a preventive contribution to preventing the transmission of covid 19 for RW 7 residents in the form of providing equipment and socializing the use of equipment, providing knowledge in dealing with the new normal period, especially in managing family finances and digital marketing to RW 7 residents and increasing the ability of the Covid 19 Task Force. Key Words: digital marketing;family’s financial; tough neighbourhood; preventive Covid 19 ; radio streaming

A GRAPH PARTITIONING TECHNIQUE TO OPTIMIZE THE PHYSICAL INTEGRATION OF FUNCTIONAL REQUIREMENTS FOR AXIOMATIC DESIGN

According to the concept of physical integration as understood in Axiomatic Design, design parameters of a product should be integrated into a single physical part or a few parts with the aim of reducing the information content, while still satisfying the independence of functional requirement. However, no specific method is suggested in the literature for determining the optimal degree of physical integration in a given design. This is particularly important with the current advancement in technologies such as additive manufacturing. As new manufacturing technologies allow physical elements to be integrated in new ways, new methods are needed to help designers optimize physical integration given the specific constraints and conflicts of each design. This study proposes an algorithm which uses graph partitioning to allow a designer to optimize the integration of functional requirements into a target number of parts, with the goal of minimizing the co-allocation of incompatible functional requirements in the same part. The operation and viability of the algorithm is demonstrated via two numerical examples and a practical example of designing a pencil.

Termination Based on Event Accrual in Per Protocol Versus Intention to Treat in the ROCKET AF Trial

Background In event‐driven clinical trials, study termination is based on accrual of a target number of primary efficacy events. For noninferiority trials in which superiority is conditionally examined, the ideal cohort in which to track event accrual is unclear. We used data from the ROCKET AF (Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared With Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation) trial to determine the effect of primary efficacy‐event tracking in the per‐protocol cohort during the on‐treatment period versus the intention‐to‐treat (ITT) cohort during the ITT period. Methods and Results ROCKET AF was terminated after accruing 429 primary efficacy events (stroke or systemic embolism) in the per‐protocol cohort during the on‐treatment period for noninferiority. We identified the date on which 429 events occurred in the ITT cohort during the ITT period. We performed noninferiority and superiority analyses based on hypothetical study termination on this date. ROCKET AF would have terminated 226 days earlier if events were tracked during the ITT period. Similar to the main trial findings, rivaroxaban would have met noninferiority versus warfarin for the primary efficacy end point (hazard ratio [HR], 0.77; 95% CI, 0.62–0.96; P <0.001). In contrast to the main trial findings, rivaroxaban would have met superiority for the primary efficacy end point (HR, 0.82; 95% CI, 0.68–0.99; P =0.038). In both termination scenarios, rivaroxaban was associated with a lower risk of intracranial hemorrhage and similar risk of other safety end points. Conclusions Clinical trial termination based on event accrual in the ITT cohort versus the per‐protocol cohort may have important implications on trial results depending on rates of study drug discontinuation and event rates off treatment.

Strategi Pemasaran 7P Restoran Bertema Autentik di Bale Raos sebagai Potensi Wisata Kuliner di Area Keraton Yogyakarta

Indications of successful management of cullinari such as a restaurant is a significant increase in the target number of tourists visiting. Therefore, it is necessary to have the right and targeted marketing strategy. This study aims to analyze and describe the marketing strategy of Bale Raos restaurant The autentic Taste in tourism area Keraton Yogyakarta. Research used qualitative methods. Informants sampled are general manager, marketing, operational manager and visitorAs of Bale Raos restaurant. Data was collected used interviews, observation, and documentation. Based on the research results show the right marketing strategy to increase quality product and service by segmenting targeting and positioning and collaboration of good product, price sale, place, promotion, people, process and physical evidance.