International Committee for the Classification of Corneal Dystrophies (IC3D) Meeting. An inaugural meeting for Ophthalmologists, Pathologists & Geneticists will be held Monday, October 17, 2005 during the Annual Meeting of the American Academy of Ophthalmology at the Hyatt McCormick hotel from 5:00 PM to 7:30 PM. The Cornea Society will sponsor this meeting with assistance from the American Academy of Ophthalmology

2005 ◽  
Vol 140 (3) ◽  
pp. 572
Keyword(s):  
American Academy ◽  
Annual Meeting ◽  
International Committee ◽  
Inaugural Meeting ◽  
Corneal Dystrophies ◽  
October 17

Corneal Dystrophy in Dutch Belted Rabbits as a Possible Model of Thiel-Behnke Subtype of Epithelial-Stromal TGFβ-Induced Corneal Dystrophy

2020 ◽  
pp. 019262332096809
Author(s):  
JoAnn C. L. Schuh ◽  
Dana L. Holve ◽  
Karen E. Mundwiler
Keyword(s):  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Corneal Opacity ◽  
Corneal Dystrophy ◽  
International Committee ◽  
Corneal Dystrophies ◽  
Transmission Electron ◽  
Oct Imaging ◽  
Small Clusters

The International Committee for Classification of Corneal Dystrophies (IC3D) categorized corneal dystrophies in humans using anatomic, genotypic, and clinicopathologic phenotypic features. Relative to the IC3D classification, a review of the veterinary literature confirmed that corneal dystrophy is imprecisely applied to any corneal opacity and to multiple poorly characterized histologic abnormalities of the cornea in animals. True corneal dystrophy occurs in mice with targeted mutations and spontaneously in pet dogs and cats and in Dutch belted (DB) rabbits, but these instances lack complete phenotyping or genotyping. Corneal dystrophy in DB rabbits can be an important confounding finding in ocular toxicology studies but has only been described once. Therefore, the ophthalmology and pathology of corneal dystrophy in 13 DB rabbits were characterized to determine whether the findings were consistent with or a possible model of any corneal dystrophy subtypes in humans. Slit lamp and optical coherence tomography (OCT) imaging were used to characterize corneal dystrophy over 4 months in young DB rabbits. The hyperechoic OCT changes correlated with light microscopic findings in the anterior stroma, consisting of highly disordered collagen fibers and enlarged keratocytes. Histochemical stains did not reveal abnormal deposits. Small clusters of 8 to 16 nm diameter curly fibers identified by transmission electron microscopy were consistent with Thiel-Behnke (TBCD) subtype of epithelial-stromal transforming growth factor β-induced dystrophies. Sporadic corneal dystrophy in DB rabbits appears to be a potential animal model of TBCD, but genotypic characterization will be required to confirm this categorization.

Corneal Dystrophies

2022 ◽  
pp. 322-340
Keyword(s):  
Late Onset ◽  
Corneal Thickness ◽  
Corneal Dystrophy ◽  
International Committee ◽  
Level Of Evidence ◽  
Corneal Dystrophies ◽  
Tgfbi Gene ◽  
Epithelial Basement Membrane ◽  
Posterior Polymorphous Corneal Dystrophy

Corneal dystrophies have classically referred to inherited, bilateral disease without systemic findings, although there are several exceptions to this definition. Hereditary pattern is not present in most patients with epithelial basement membrane dystrophy (EBMD). Unilateral corneal changes may be found in some patients with posterior polymorphous corneal dystrophy (PPCD). TGFBI gene mutation (p.His572del) is associated with a unilateral, late-onset variant of lattice corneal dystrophy. Among all dystrophies, macular corneal dystrophy and posterior amorphous corneal dystrophy are associated with decreased corneal thickness. The International Committee for Classification of Corneal Dystrophies (IC3D) was created in 2005 to revise the corneal dystrophy nomenclature and create a current and accurate corneal dystrophy classification system. Evidential categories were created in the IC3D classification for reflecting the natural evolution of a corneal dystrophy and indicate the level of evidence supporting the existence of a given dystrophy.

Introduction

2011 ◽  
Vol 40 (3) ◽  
pp. 1-3
Author(s):  
Christopher Driscoll
Keyword(s):  
African American ◽  
American Academy ◽  
Annual Meeting ◽  
Hip Hop ◽  
Religious Studies ◽  
Hip Hop Culture

At the 2010 annual meeting of the American Academy of Religion held in Atlanta, GA, a group of young scholars organized a wildcard session titled “What’s This ‘Religious’ in Hip Hop Culture?” The central questions under investigation by the panel were 1) what about hip hop culture is religious? and 2) how are issues of theory and method within African American religious studies challenged and/or rethought because of the recent turn to hip hop as both subject of study and cultural hermeneutic. Though some panelists challenged this “religious” in hip hop, all agreed that hip hop is of theoretical and methodological import for African American religious studies and religious studies in general. This collection of essays brings together in print many findings from that session and points out the implications of hip hop's influence on religious scholars' theoretical and methodological concerns.

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