Age-Related Macular Degeneration and Optic Disk Cupping: The Beaver Dam Eye Study

2006 ◽  
Vol 141 (3) ◽  
pp. 494-497 ◽  
Author(s):  
Ellen R. Hall ◽  
Barbara E.K. Klein ◽  
Michael D. Knudtson ◽  
Stacy M. Meuer ◽  
Ronald Klein
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Optic Disk ◽  
Age Related ◽  
Beaver Dam

scholarly journals Skin Intrinsic Fluorescence and Age-Related Macular Degeneration: The Beaver Dam Eye Study

2017 ◽  
Vol 58 (14) ◽  
pp. 6328 ◽  
Author(s):  
Ronald Klein ◽  
Kristine E. Lee ◽  
John D. Maynard ◽  
Stacy M. Meuer ◽  
Ronald E. Gangnon ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Intrinsic Fluorescence ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Beaver Dam ◽  
Skin Intrinsic Fluorescence

scholarly journals The Relationship of Atherosclerosis to the 10-Year Cumulative Incidence of Age-related Macular Degeneration: The Beaver Dam Studies

Ophthalmology ◽  
2013 ◽  
Vol 120 (5) ◽  
pp. 1012-1019 ◽  
Author(s):  
Ronald Klein ◽  
Karen J. Cruickshanks ◽  
Chelsea E. Myers ◽  
Theru A. Sivakumaran ◽  
Sudha K. Iyengar ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Cumulative Incidence ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Beaver Dam ◽  
Relationship Of ◽  
The Relationship

Frailty and Age-related Macular Degeneration: The Beaver Dam Eye Study

2005 ◽  
Vol 140 (1) ◽  
pp. 129-131 ◽  
Author(s):  
Ronald Klein ◽  
Barbara E.K. Klein ◽  
Michael D. Knudtson
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Beaver Dam

scholarly journals Small Drusen and Age-Related Macular Degeneration: The Beaver Dam Eye Study

2015 ◽  
Vol 4 (3) ◽  
pp. 425-440 ◽  
Author(s):  
Ronald Klein ◽  
Chelsea Myers ◽  
Kristine Lee ◽  
Ronald Gangnon ◽  
Theru Sivakumaran ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Beaver Dam

Age-related macular degeneration and optic disk morphology

1999 ◽  
Vol 127 (2) ◽  
pp. 220-221 ◽  
Author(s):  
Wido M Budde ◽  
Jost B Jonas ◽  
Ulrich Schönherr
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Optic Disk ◽  
Age Related

Optic disk appearance in advanced age-related macular degeneration

2004 ◽  
Vol 138 (1) ◽  
pp. 38-45 ◽  
Author(s):  
Simon K. Law ◽  
Yong Ho Sohn ◽  
Douglas Hoffman ◽  
Kent Small ◽  
Anne L. Coleman ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Advanced Age ◽  
Optic Disk ◽  
Age Related

scholarly journals Automated Segmentation Methods of Drusen to Diagnose Age-Related Macular Degeneration Screening in Retinal Images

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Young Jae Kim ◽  
Kwang Gi Kim
Keyword(s):  
Macular Degeneration ◽  
High Reliability ◽  
Median Filter ◽  
Age Related Macular Degeneration ◽  
Optic Disk ◽  
Fundus Image ◽  
Difference Image ◽  
Age Related ◽  
Renyi’S Entropy ◽  
The Difference

Existing drusen measurement is difficult to use in clinic because it requires a lot of time and effort for visual inspection. In order to resolve this problem, we propose an automatic drusen detection method to help clinical diagnosis of age-related macular degeneration. First, we changed the fundus image to a green channel and extracted the ROI of the macular area based on the optic disk. Next, we detected the candidate group using the difference image of the median filter within the ROI. We also segmented vessels and removed them from the image. Finally, we detected the drusen through Renyi’s entropy threshold algorithm. We performed comparisons and statistical analysis between the manual detection results and automatic detection results for 30 cases in order to verify validity. As a result, the average sensitivity was 93.37% (80.95%~100%) and the average DSC was 0.73 (0.3~0.98). In addition, the value of the ICC was 0.984 (CI: 0.967~0.993, p<0.01), showing the high reliability of the proposed automatic method. We expect that the automatic drusen detection helps clinicians to improve the diagnostic performance in the detection of drusen on fundus image.

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