Advanced maternal age (AMA) is an independent risk factor for intrauterine growth restriction (IUGR)

2004 ◽  
Vol 191 (6) ◽  
pp. S78
Author(s):  
Anthony Odibo ◽  
Raegan McDonald ◽  
Deborah Nelson ◽  
David Stamilio ◽  
Harish Sehdev ◽  
...  
2006 ◽  
Vol 23 (5) ◽  
pp. 325-328 ◽  
Author(s):  
Anthony Odibo ◽  
Deborah Nelson ◽  
David Stamilio ◽  
Harish Sehdev ◽  
George Macones

2017 ◽  
Vol 45 (7) ◽  
Author(s):  
Ulrich Pecks ◽  
Werner Rath ◽  
Dirk O. Bauerschlag ◽  
Nicolai Maass ◽  
Thorsten Orlikowsky ◽  
...  

AbstractAim:Intrauterine growth restriction (IUGR) is an independent risk factor for the development of cardiovascular diseases later in life. The mechanisms whereby slowed intrauterine growth confers vascular risk are not clearly established. In general, a disturbed cholesterol efflux has been linked to atherosclerosis. The capacity of serum to accept cholesterol has been repeatedly evaluated in clinical studies by the use of macrophage-based cholesterol efflux assays and, if disturbed, precedes atherosclerotic diseases years before the clinical diagnosis. We now hypothesized that circulating cholesterol acceptors in IUGR sera specifically interfere with cholesterol transport mechanisms leading to diminished cholesterol efflux.Methods:RAW264.7 cells were used to determine efflux of [Results:Cholesterol efflux was lower in IUGR as compared to controls [controls: mean 7.7% fractional [Conclusions:Reduced cholesterol efflux in IUGR could account for the enhanced risk of developing cardiovascular diseases later in life.


2008 ◽  
Vol 199 (6) ◽  
pp. S113
Author(s):  
Shimrit Yaniv Salem ◽  
Amalia Levy ◽  
Arnon Wiznitzer ◽  
Gershon Holcberg ◽  
Moshe Mazor ◽  
...  

2019 ◽  
Author(s):  
Jie Chen ◽  
Yue Lian Yang

Abstract Background Twins pregnancy can cause a lot of disease, especially monochorionic twin pregnancies, the prenatal infant will have many diseases and have high mortality rate. According to analysis and compare of the twin pregnancy, especially pregnant woman and puerpera’s situation and complication and baby’s situation; we hope we can find the reason which causes the fetus growth restrain of monochorionic twin pregnancies. So we can provide some reference for the prenatal health care, complication prevention and prenatal outcome. Methods We divided 489 cases of twin pregnancies into two groups: monochorionic twin and dichorionic twin and compared the clinical features of them. At last, we used the logistic regression analysis method to analyze the risk factors of selective intrauterine growth restriction(sIUGR). Results The incidences of premature rupture of membranes and sIUGR were significant higher in monochorionic twin and twin-twin transfusion syndrome (TTTS) only exists in monochorionic twin. The weight of the newborn babies(both big and small babies)were significant lower in Monochorionic twin. The neonatal transfer rate was significant higher in monochorionic twin. Gestational weeks and weight of newborn babies are the high risk factors of sIUGR. Conclusions The type of chorion has a great influence to the pregnant period and the ending of maternal women. Monochorionic is a high risk factor of the sIUGR, which means that the main cause of sIUGR is from placenta, so it is a kind of “placental origin disease”.


Author(s):  
Varuni Sharma ◽  
Navin Shukla

Background: Hypertensive disorders in pregnancy (HDP) remain a major global health issue not only because of the associated high adverse maternal outcomes but there is a close accompaniment of significant perinatal morbidity. Intrauterine growth restriction (IUGR), a condition that occurs due to various reasons, is an important cause of fetal. It has been defined as a rate of fetal growth that is less than normal in light of the growth potential of that specific infant. The aim of this study is to evaluate the prevalence and risk factor for IUGR among the PIH patient.Methods: A prospective randomized controlled clinical trial of 25 patients was carried out in Kamla Raja Hospital and Out Patient Department of Gajra Raja Medical College, Gwalior from October 6th to October 2007. A total number of 25 patients were included in study of PIH.Results: conclude that the prevalence and risk factor for IUGR among the PIH patient.  The Distribution prevalence of sociodemographical factor for IUGR among PIH patient is statistically not significant. It concluded that there is no significance (no effect) between risk factors of IUGR among the pregnancy induced hypertension.Conclusions: The prevalence of IUGR found in this study. There is need to increase awareness among medical and paramedical personnel on the need for early referral of women with previous history of IUGR, preeclampsia, multiple gestations, gestational diabetes and obesity for specialist care as they have a higher risk.


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