92: The effect of exposure to antenatal corticosteroids on the admission rates of late preterm infants to special care nurseries

2007 ◽  
Vol 197 (6) ◽  
pp. S40
Author(s):  
Karin Fuchs ◽  
Omar Maurice Young ◽  
Phyllis Gyamfi ◽  
David Bateman ◽  
Cynthia Gyamfi
Keyword(s):  
Preterm Infants ◽  
Special Care ◽  
Late Preterm ◽  
Antenatal Corticosteroids ◽  
Late Preterm Infants ◽  
Admission Rates

scholarly journals Antenatal Corticosteroids for Late-Preterm Infants: A Decision-Analytic and Economic Analysis

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Jamie A. Bastek ◽  
Holly Langmuir ◽  
Laxmi A. Kondapalli ◽  
Emmanuelle Paré ◽  
Joanna E. Adamczak ◽  
...  
Keyword(s):  
At Risk ◽  
Cost Effectiveness ◽  
Preterm Infants ◽  
Cost Effective ◽  
Chronic Respiratory Disease ◽  
Late Preterm ◽  
Base Case ◽  
Antenatal Corticosteroids ◽  
Late Preterm Infants ◽  
Patients At Risk

Objectives. Antenatal corticosteroids (ACS) are not routinely administered to patients at risk for delivery between 34 and 36 6/7 weeks. Our objective was to determine whether ACS are cost-effective for late-preterm infants at risk for imminent preterm delivery. We hypothesized that the preferred strategy <36 weeks would include ACS while the preferred strategy ≥36 weeks would not. Methods. We performed decision-analytic and cost-effectiveness analyses to determine whether ACS was cost-effective at 34, 35, and 36 weeks. We conducted a literature review to determine probability, utility, and cost estimates absent of patient-level data. Base-case cost-effectiveness analysis, univariable sensitivity analysis, and Monte Carlo simulation were performed. A threshold of $100,000/QALY was considered cost-effective. Results. The incremental cost-effectiveness ratio favored the administration of a full course of ACS at 34, 35, and 36 weeks ($62,888.25/QALY, $64,425.67/QALY, and $64,793.71/QALY, resp.). A partial course of ACS was not cost-effective. While ACS was the consistently dominant strategy for acute respiratory outcomes, all models were sensitive to changes in variables associated with chronic respiratory disease. Conclusions. Our findings suggest that the administration of ACS to patients at risk of imminent delivery 34-36 weeks could significantly reduce the cost and acute morbidity associated with late-preterm birth.

Effectiveness of Antenatal Corticosteroids in Reducing Respiratory Disorders in Late Preterm Infants: Randomized Clinical Trial

2011 ◽  
Vol 66 (8) ◽  
pp. 473-474
Author(s):  
Ana Maria Feitosa Porto ◽  
Isabela Cristina Coutinho ◽  
Jailson Barros Correia ◽  
Melania Maria Ramos Amorim
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Preterm Infants ◽  
Late Preterm ◽  
Antenatal Corticosteroids ◽  
Respiratory Disorders ◽  
Late Preterm Infants

scholarly journals Effectiveness of antenatal corticosteroids in reducing respiratory disorders in late preterm infants: randomised clinical trial

BMJ ◽  
2011 ◽  
Vol 342 (apr12 1) ◽  
pp. d1696-d1696 ◽  
Author(s):  
A. M. F. Porto ◽  
I. C. Coutinho ◽  
J. B. Correia ◽  
M. M. R. Amorim
Keyword(s):  
Clinical Trial ◽  
Preterm Infants ◽  
Randomised Clinical Trial ◽  
Late Preterm ◽  
Antenatal Corticosteroids ◽  
Respiratory Disorders ◽  
Late Preterm Infants

Antenatal corticosteroids in late preterm infants

BMJ ◽  
2011 ◽  
Vol 342 (apr12 1) ◽  
pp. d1614-d1614 ◽  
Author(s):  
D. Roberts
Keyword(s):  
Preterm Infants ◽  
Late Preterm ◽  
Antenatal Corticosteroids ◽  
Late Preterm Infants

scholarly journals Assessment of Thyroid Functions in Late Preterm Infants of Mothers on Antenatal Steroids

2021 ◽  
Vol 2 (4) ◽  
pp. 18-29
Author(s):  
Rasha T Hamza ◽  
Amira I Hamed ◽  
Basma B B Hassan ◽  
Wafaa O Ahmed
Keyword(s):  
Preterm Infants ◽  
Late Preterm ◽  
Antenatal Corticosteroids ◽  
Free T4 ◽  
Cross Sectional ◽  
Late Preterm Infants ◽  
The Third ◽  
Antenatal Steroids ◽  
Serum T4 ◽  
Group 1

Purpose: The study examined the effect of antenatal steroids on thyroid functions in late preterm infants on the third to the seventh day of life. Patients and Methods: A comparative Cross-Sectional study was conducted on 75 neonates admitted to NICU in the first week of life. They were divided according to exposure to antenatal steroids into three groups. First group: exposed to complete course of ANS. Second group: exposed to partial course of ANS. The third group: not exposed to ANS. Serum samples were obtained from selected cases free T3, Free T4, and TSH levels in the third day of life, compared to the cut of levels currently available (the TSH reference range is (1.7 to 9.1 mU per L), T4 should be greater than( 10 mcg per dL). Using Eleusis and Cubase analyzers kits (Roche Diagnostics, Indianapolis, IN, USA) by ELISA (enzyme-linked immune sorbent assay) technique. Results: The study showed that there were significantly higher serum T4 levels in group 1 that was exposed to a complete course compared to group 2 (partial course) and 3 (Third group). There were no significant differences in serum TSH, T3 levels between groups. The current study found a decreased incidence of the ROP, NEC and BPD among group 1 as compared to the other two groups although was non statistically significant. In addition, the complete course of ANS had delayed the date of delivery (P=0.04) as compared to the partial course in the current study. Conclusion: Antenatal corticosteroids can influence thyroid function in late preterm infants as serum T4 was significantly higher in infants exposed to complete course compared to those who were exposed to partial course or did not receive antenatal corticosteroids.

Late Preterm Infants Require Preventive Vigilance

2008 ◽  
Vol 42 (4) ◽  
pp. 30-31
Author(s):  
DOUG BRUNK
Keyword(s):  
Preterm Infants ◽  
Late Preterm ◽  
Late Preterm Infants
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