Fetal fibronectin testing for prevention of preterm birth in singleton pregnancies with threatened preterm labor: a systematic review and metaanalysis of randomized controlled trials

2016 ◽  
Vol 215 (4) ◽  
pp. 431-438 ◽  
Author(s):  
Vincenzo Berghella ◽  
Gabriele Saccone
Keyword(s):  
Systematic Review ◽  
Preterm Birth ◽  
Randomized Controlled Trials ◽  
Preterm Labor ◽  
Controlled Trials ◽  
Fetal Fibronectin ◽  
Randomized Controlled ◽  
Threatened Preterm Labor ◽  
Singleton Pregnancies

scholarly journals Cervical Pessaries for the Prevention of Preterm Birth: A Systematic Review

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Sophie M. S. Liem ◽  
Mariëlle G. van Pampus ◽  
Ben Willem J. Mol ◽  
Dick J. Bekedam
Keyword(s):  
Systematic Review ◽  
Preterm Birth ◽  
Cohort Studies ◽  
Randomized Controlled Trials ◽  
Randomized Clinical Trials ◽  
Obstetric Care ◽  
Potential Effect ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Cervical Pessary

Introduction. Reduction of preterm birth is a major goal in obstetric care. We performed a systematic review of randomized controlled trials and cohort studies on the effectiveness of the cervical pessary to prevent preterm birth.Methods. We searched the electronic databases of MEDLINE and Embase from inception until April 2012 to identify studies investigating treatment with a cervical pessary to prevent preterm birth. We constructed two-by-two tables for delivery before 28, 34, and 37 weeks of gestation and calculated relative risks (RRs) with 95% confidence intervals.Results. The search revealed 103 potentially eligible abstracts of which six cohort studies and four randomized controlled trials (RCTs) investigated the effectiveness of the pessary. One RCT (n=380) demonstrated a lower delivery rate prior to 34 weeks (RR 0.24; 95% CI 0.13–0.43) in the pessary group, while another RCT (n=108) showed no positive effect of pessary for delivery before 34 weeks (RR 1.73; 95% CI 0.43–6.88). Two older quasi randomized studies and cohort studies indicated potential effect of the pessary.Conclusions. Available randomized and nonrandomized studies indicate potential effectiveness of a cervical pessary in the prevention of preterm birth. More randomized clinical trials are needed before this device can be used in clinical practice.

Systematic review and meta‐analysis of randomized controlled trials of atosiban versus nifedipine for inhibition of preterm labor

2019 ◽  
Vol 145 (2) ◽  
pp. 139-148 ◽  
Author(s):  
Aya Ashraf Ali ◽  
Ahmed Kamal Sayed ◽  
Loalo'a El Sherif ◽  
Gihan Ossam Loutfi ◽  
Abdullah Mahmoud Mohamed Ahmed ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Preterm Labor ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled
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