scholarly journals Maximum vertical pocket versus amniotic fluid index: assessing adverse pregnancy outcomes in patients with polyhydramnios

2022 ◽  
Vol 226 (1) ◽  
pp. S314-S315
Author(s):  
Alexandria Kraus ◽  
Lauren Kucirka ◽  
Hina Shah ◽  
Juan Prieto ◽  
Nancy Chescheir ◽  
...  
Keyword(s):  
Amniotic Fluid ◽  
Pregnancy Outcomes ◽  
Adverse Pregnancy Outcomes ◽  
Amniotic Fluid Index ◽  
Adverse Pregnancy

scholarly journals Amniotic Fluid Assessment: Amniotic Fluid Index Versus Maximum Vertical Pocket

2017 ◽  
Vol 33 (4) ◽  
pp. 280-283 ◽  
Author(s):  
Jacquelyn Coombe-Patterson
Keyword(s):  
Amniotic Fluid ◽  
Pregnancy Outcomes ◽  
Adverse Outcome ◽  
Well Being ◽  
Fluid Volume ◽  
The Other ◽  
Amniotic Fluid Index ◽  
Amniotic Fluid Volume ◽  
Fluid Assessment ◽  
Adverse Pregnancy

Amniotic fluid assessment is vital to fetal well-being. Accurately diagnosing an amniotic fluid abnormality can aid in the proper management of a pregnancy at risk for an adverse outcome. Sonography is the most common way to assess amniotic fluid volume throughout a pregnancy; however, the most accurate technique, amniotic fluid index or maximum vertical pocket, is yet to be determined. Dye-dilution techniques are the most accurate way to measure amniotic fluid volume, but they are invasive and can be performed only at the time of a cesarean delivery. Multiple studies have been performed to determine the accuracy of the amniotic fluid index and maximum vertical pocket methods when diagnosing amniotic fluid volume abnormalities. Based on the studies reviewed in this article, neither method stands out as superior to the other when it comes to diagnosing amniotic fluid abnormalities during pregnancy. However, the maximum vertical pocket should also always be considered when an amniotic fluid abnormality is suspected because the amniotic fluid index overdiagnoses amniotic fluid abnormalities, leading to increased rates of pregnancy intervention and the potential for adverse pregnancy outcomes.

Association between Thiopurines Use and Pregnancy Outcomes in Female Patients with Inflammatory Bowel Disease: A Meta-analysis

2020 ◽  
Vol 26 ◽  
Author(s):  
Yang Zhang ◽  
Dandan Li ◽  
Heng Guo ◽  
Weina Wang ◽  
Xingang Li ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Preterm Birth ◽  
Spontaneous Abortion ◽  
Bowel Disease ◽  
Pregnancy Outcomes ◽  
Congenital Malformations ◽  
Meta Analysis ◽  
Adverse Pregnancy Outcomes ◽  
Inflammatory Bowel ◽  
Adverse Pregnancy

Background: Conflicting data exist regarding the influence of thiopurines exposure on adverse pregnancy outcomes in female patients with inflammatory bowel disease (IBD). Objective: The aim of this study was to provide an up-to-date and comprehensive assessment of the safety of thiopurines in pregnant IBD women. Methods: All relevant articles reporting pregnancy outcomes in women with IBD received thiopurines during pregnancy were identified from the databases (PubMed, Embase, Cochrane Library, and ClinicalTrials.gov) with the publication data up to April 2020. Data of included studies were extracted to calculate the relative risk (RR) of multiple pregnancy outcomes: congenital malformations, low birth weight (LBW), preterm birth, small for gestational age (SGA), and spontaneous abortion. The meta-analysis was performed using the random-effects model. Results: Eight studies matched with the inclusion criteria and a total of 1201 pregnant IBD women who used thiopurines and 4189 controls comprised of women with IBD received drugs other than thiopurines during pregnancy were included. Statistical analysis results demonstrated that the risk of preterm birth was significantly increased in the thiopurine-exposed group when compared to IBD controls (RR, 1.34; 95% CI, 1.00-1.79; p=0.049; I 2 =41%), while no statistically significant difference was observed in the incidence of other adverse pregnancy outcomes. Conclusion: Thiopurines’ use in women with IBD during pregnancy is not associated with congenital malformations, LBW, SGA, or spontaneous abortion, but appears to have an association with an increased risk of preterm birth.

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