Differences in IL-10 and IL-12 production patterns and differences in the effects of acute ethanol treatment on macrophages in vivo and in vitro

Alcohol ◽  
2005 ◽  
Vol 37 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Stephen B. Pruett ◽  
Ruping Fan ◽  
Qiang Zheng ◽  
Carlton Schwab
1997 ◽  
Vol 122 (5) ◽  
pp. 956-962 ◽  
Author(s):  
T. Ibbotson ◽  
M. J. Field ◽  
P. R. Boden

1981 ◽  
Vol 241 (2) ◽  
pp. G176-G181
Author(s):  
R. S. Green ◽  
R. G. MacDermid ◽  
R. L. Scheig ◽  
J. J. Hajjar

The acute effect of ethanol on amino acid absorption across the in vivo rat intestine was studied using single-pass continuous perfusion and recirculation techniques. The single-pass steady-state perfusion was used to examine the effect on the entire small intestine and recirculation perfusion to examine the effect on short intestinal segments and to limit ethanol absorption. Unlike the in vitro findings of other investigators, ethanol does not cause inhibition of net amino acid absorption in vivo unless the alcohol is perfused in 2 M or higher concentrations. The inhibition that is observed at these concentrations is very likely due to severe injury and shedding of intestinal cells as evidenced by an increased recovery of DNA in the perfusates. The findings suggest that acute ethanol administration, in concentrations that are comparable to those found in the upper intestines of humans after the ingestion of moderate doses of alcohol, does not have a prominent effect on amino acid absorption across the in situ rat intestine. Under these conditions, the ethanol inhibition of active absorption is masked by enhanced diffusion of the amino acids across the intestine.


2013 ◽  
Vol 17 (2) ◽  
pp. 184-190 ◽  
Author(s):  
Ying Wan ◽  
Shuang Jiang ◽  
Li-Hua Lian ◽  
Ting Bai ◽  
Peng-He Cui ◽  
...  

Life Sciences ◽  
1987 ◽  
Vol 40 (1) ◽  
pp. 19-28 ◽  
Author(s):  
Christina Gianoulakis ◽  
Alan Barcomb
Keyword(s):  

1976 ◽  
Vol 25 (3) ◽  
pp. 329-335 ◽  
Author(s):  
Jatinder M. Khanna ◽  
Harold Kalant ◽  
Yuvonne Yee ◽  
Sylvia Chung ◽  
Albert J. Siemens

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