Exercise-Induced Polymorphic Ventricular Tachycardia in Adults Without Structural Heart Disease

2008 ◽  
Vol 101 (8) ◽  
pp. 1142-1146 ◽  
Author(s):  
Justin Hong-jie Tan ◽  
Melvin M. Scheinman
2013 ◽  
Vol 38 (11) ◽  
pp. 463-496 ◽  
Author(s):  
Indrajit Choudhuri ◽  
Mamatha Pinninti ◽  
Muhammad R. Marwali ◽  
Jasbir Sra ◽  
Masood Akhtar

2016 ◽  
Vol 5 (1) ◽  
pp. 45 ◽  
Author(s):  
Krystien VV Lieve ◽  
◽  
Arthur A Wilde ◽  
Christian van der Werf ◽  
◽  
...  

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but severe genetic cardiac arrhythmia disorder, with symptoms including syncope and sudden cardiac death due to polymorphic VT or ventricular fibrillation typically triggered by exercise or emotions in the absence of structural heart disease. The cornerstone of medical therapy for CPVT is β -blockers. However, recently flecainide has been added to the therapeutic arsenal for CPVT. In this review we summarise current data on the efficacy and role of flecainide in the treatment of CPVT.


2020 ◽  
Vol 21 ◽  
Author(s):  
Michelle Audrey Darmadi ◽  
Axel Duval ◽  
Hanaa Khadraoui ◽  
Alberto N. Romero ◽  
Blanca Simon ◽  
...  

2017 ◽  
Vol 2 (43) ◽  
pp. 18-22
Author(s):  
Agnieszka Wojdyła-Hordyńska ◽  
Grzegorz Hordyński ◽  
Patrycja Pruszkowska-Skrzep ◽  
Oskar Kowalski

Nonsustained ventricular tachycardia (NSVT) is usually a mild entity without serious clinical consequences. Nevertheless, exercise-induced NSVT, and short cycle length of tachycardia, significant arrhythmia burden may predict increased cardiac mortality. NSVT is defined as 3 or more consecutive ventricular beats with a rate over 100 beats/min or more, lasting less than 30 s, that can be diagnosed on the basis of electrocardiography, Holter, telemetry, cardiac monitors or exercise test, after careful wide QRS tachycardia differential diagnostics, artefacts, supraventricular tachycardia with aberration, Hiss-Purkinje block or additional atrio-ventricular pathway descending conduction exclusion. It is necessary to assess homogeneity of the tachycardia (monomorphic or polymorphic), exclude ischemic, structural and genetic heart disease. The treatment is based on observation, farmacotherapy (mainly with beta-blockers, calcium channels blockers and antiarrhythmics) and percutaneous ablation. Implantable cardioverter-defibrillator is not recommended. The prognosis is usually good.


Heart Rhythm ◽  
2019 ◽  
Vol 16 (7) ◽  
pp. 1021-1027 ◽  
Author(s):  
Tomofumi Nakamura ◽  
Benjamin Schaeffer ◽  
Shinichi Tanigawa ◽  
Rahul G. Muthalaly ◽  
Roy M. John ◽  
...  

Author(s):  
Krystien VV Lieve ◽  
Arthur A Wilde ◽  
Christian van der Werf ◽  
◽  
◽  
...  

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but severe genetic cardiac arrhythmia disorder, with symptoms including syncope and sudden cardiac death due to polymorphic VT or ventricular fibrillation typically triggered by exercise or emotions in the absence of structural heart disease. The cornerstone of medical therapy for CPVT is β -blockers. However, recently flecainide has been added to the therapeutic arsenal for CPVT. In this review we summarise current data on the efficacy and role of flecainide in the treatment of CPVT.


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