The Association Between Serum Calcium Levels and Short-Term Mortality in Patients with Chronic Heart Failure

Introduction: Soluble suppression of tumorigenicity-2 (sST2) has been considered as a prognostic factor of cardiovascular disease. However, the prognostic value of sST2 concentration in chronic heart failure remains to be summarized. Methods: We searched PubMed, Embase, and Web of Science for eligible studies up to January 1, 2020. Data extracted from articles and provided by authors were used in agreement with the PRISMA statement. The endpoints were all-cause mortality (ACM), cardiovascular mortality (CVM)/heart failure-related hospitalization (HFH), and all-cause mortality (ACM)/heart failure-related readmission (HFR). Results: A total of 11 studies with 5,121 participants were included in this analysis. Higher concentration of sST2 predicted the incidence of long-term ACM (hazard ratio [HR]: 1.03, 95% confidence interval [CI]: 1.02–1.04), long-term ACM/HFR (HR: 1.42, CI: 1.27–1.59), and long-term CVM/HFH (HR: 2.25, CI: 1.82–2.79), regardless of short-term ACM/HFR (HR: 2.31, CI: 0.71–7.49). Conclusion: Higher sST2 concentration at baseline is associated with increasing risk of long-term ACM, ACM/HFR, and CVM/HFH and can be a tool for the prognosis of chronic heart failure.

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Short-Term Change in Distance Walked in 6 Min Is an Indicator of Outcome in Patients With Chronic Heart Failure in Clinical Practice

Journal of the American College of Cardiology ◽

10.1016/j.jacc.2006.02.061 ◽

2006 ◽

Vol 48 (1) ◽

pp. 99-105 ◽

Cited By ~ 50

Author(s):

Andrea Passantino ◽

Rocco Lagioia ◽

Filippo Mastropasqua ◽

Domenico Scrutinio

Keyword(s):

Heart Failure ◽

Clinical Practice ◽

Chronic Heart Failure ◽

Short Term ◽

Short Term Change ◽

Term Change

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Short-term and long-term hemodynamic and clinical effects of metoprolol alone and combined with amlodipine in patients with chronic heart failure

American Heart Journal ◽

10.1016/s0002-8703(99)70110-9 ◽

1999 ◽

Vol 138 (2) ◽

pp. 261-268 ◽

Cited By ~ 14

Author(s):

Marrick L. Kukin ◽

Ronald S. Freudenberger ◽

Michael M. Mannino ◽

Jill Kalman ◽

Marilyn Steinmetz ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Clinical Effects ◽

Short Term

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The effects of short term statin treatment on left ventricular function and inflammatory markers in patients with chronic heart failure

International Journal of Cardiology ◽

10.1016/j.ijcard.2006.11.152 ◽

2008 ◽

Vol 123 (2) ◽

pp. 102-107 ◽

Cited By ~ 40

Author(s):

Cemil Gürgün ◽

Müge Ildızlı ◽

Oğuz Yavuzgil ◽

Aytül Sin ◽

Anıl Apaydın ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Left Ventricular Function ◽

Ventricular Function ◽

Inflammatory Markers ◽

Statin Treatment ◽

Left Ventricular ◽

Short Term

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Influence of short-term oral hydralazine therapy on exercise hemodynamics in patients with severe chronic heart failure

The American Journal of Cardiology ◽

10.1016/0002-9149(79)90186-3 ◽

1979 ◽

Vol 44 (6) ◽

pp. 1183-1189 ◽

Cited By ~ 68

Author(s):

Stanley A. Rubin ◽

Kanu Chatterjee ◽

Thomas A. Ports ◽

Harris J. Gelberg ◽

Bruce H. Brundage ◽

...

Keyword(s):

Heart Failure ◽

Chronic Heart Failure ◽

Short Term ◽

Severe Chronic Heart Failure ◽

Exercise Hemodynamics

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Usefulness of right ventricular contraction pressure index to predict short-term mortality and right heart failure in patients who underwent continuous-flow left ventricular assist device implantation

The International Journal of Artificial Organs ◽

10.1177/0391398819868480 ◽

2019 ◽

Vol 43 (1) ◽

pp. 25-36 ◽

Cited By ~ 1

Author(s):

Koray Kalenderoğlu ◽

Tolga Sinan Güvenç ◽

Müge Taşdemir Mete ◽

Hüseyin Kuplay ◽

Semra Ağustos ◽

...

Keyword(s):

Heart Failure ◽

Right Ventricular ◽

Right Heart Failure ◽

Left Ventricular ◽

Ventricular Contraction ◽

Short Term ◽

Right Heart ◽

Ventricular Assist ◽

Pressure Index ◽

Short Term Mortality

Background: Right ventricular stroke work index is a useful but invasively measured parameter that can be used to predict right heart failure following continuous-flow left ventricular assist device implantation. Right ventricular contraction pressure index is a novel parameter that was developed to measure right ventricular stroke work index with echocardiography. We aimed to investigate the clinical usefulness of right ventricular contraction pressure index to predict short-term mortality and right heart failure in patients who underwent continuous-flow left ventricular assist device implantation. Methods: A total of 49 patients who participated in institutional advanced heart failure registry and underwent continuous-flow left ventricular assist device implantation with a bridge-to-candidacy indication were analyzed retrospectively. Right ventricular contraction pressure index was calculated using offline measurements. Demographic, clinical and outcome data were obtained from the registry data. Patients were grouped according to right ventricular contraction pressure index quartiles. Results: Patients within the lowest right ventricular contraction pressure index quartile had a trend toward higher short-term mortality (46.2%, p = 0.056) and combined short-term mortality and definitive right heart failure (53.8%, p = 0.054) at 15th day postoperatively. Similarly, short-term survival or survival free of definite right heart failure were significantly lower in the lowest right ventricular contraction pressure index quartile (log-rank p = 0.045 and log-rank p = 0.03, respectively). In a proportional hazards model that included echocardiographic parameters, right ventricular contraction pressure index was an independent predictor for short-term mortality (odds ratio: 6.777, 95% confidence interval: 1.118–41.098, p = 0.037), but not for combined short-term mortality and definite right heart failure. No such associations were found for long-term mortality. Right ventricular contraction pressure index had a statistically significant correlation with invasively measured pulmonary capillary wedge pressure, pulmonary vascular resistance, mean pulmonary pressure, and right ventricular stroke work index. Conclusion: Right ventricular contraction pressure index was found as a useful parameter for determining short-term postoperative mortality in patients undergoing continuous-flow left ventricular assist device implantation.

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