LIVER TRANSPLANTATION AND DEATH WITHIN 4 MONTHS OF SUSPECTED DRUG-INDUCED LIVER INJURY (DILI) FROM AMOXICILLIN

2018 ◽  
Vol 121 (5) ◽  
pp. S73 ◽  
Author(s):  
S. Alagheband ◽  
P. Stewart ◽  
G. Marshall
2012 ◽  
Vol 18 (7) ◽  
pp. 803-810 ◽  
Author(s):  
Stepan Sembera ◽  
Craig Lammert ◽  
Jayant A. Talwalkar ◽  
Schuyler O. Sanderson ◽  
John J. Poterucha ◽  
...  

PLoS ONE ◽  
2017 ◽  
Vol 12 (12) ◽  
pp. e0189436 ◽  
Author(s):  
Valentina Peta ◽  
Chantal Tse ◽  
Hugo Perazzo ◽  
Mona Munteanu ◽  
Yen Ngo ◽  
...  

Author(s):  
Manuel de la Torre-Aláez ◽  
Mercedes Iñarrairaegui

Autoimmune hepatitis (AIH) was the first liver disease for which an effective therapeutic intervention was carried out, using prednisolone; its usefulness was demonstrated in several clinical trials. Nevertheless, AIH still remains a difficult diagnosis in some cases, because it is necessary to dismiss other possible diagnoses, and perhaps due to it being a heterogeneous disease. The relationship between drug-induced liver injury (DILI) and AIH is complex and not fully understood. There are three possible scenarios: (1) DILI with a strong immunoallergic component mimicking AIH; (2) AIH mimicking a DILI due to drug exposure and (3) AIH triggered by exposure to an offending drug (drug-induced AIH). Drug-induced AIH is well described and documented for some drugs such as nitrofurantoin and minocycline. Histologically distinguishing DILI from AIH remains a challenge. We present an interesting case report which met serologic criteria and histological confirmation to establish AIH, but discontinuation of a suspected drug resolved hypertransaminasaemia.


Kanzo ◽  
2011 ◽  
Vol 52 (6) ◽  
pp. 356-360
Author(s):  
Toshikuni Suda ◽  
Kazuyoshi Suzuki ◽  
Shogo Adachi ◽  
Kagemasa Kagawa ◽  
Hiroki Saito ◽  
...  

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