Genome-wide association study on reproductive traits in Jinghai Yellow Chicken

2015 ◽  
Vol 163 ◽  
pp. 30-34 ◽  
Author(s):  
G.X. Zhang ◽  
Q.C. Fan ◽  
J.Y. Wang ◽  
T. Zhang ◽  
Q. Xue ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Jinghai Yellow Chicken

scholarly journals Genome-Wide Association Study for Reproductive Traits in a Duroc Pig Population

Animals ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 732 ◽  
Author(s):  
Zhang ◽  
Chen ◽  
Ye ◽  
He ◽  
Huang ◽  
...  
Keyword(s):  
Association Study ◽  
Candidate Genes ◽  
Litter Size ◽  
Production Efficiency ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Genome Wide Association ◽  
Litter Weight ◽  
Genome Wide ◽  
A Genome

In the pig industry, reproductive traits constantly influence the production efficiency. To identify markers and candidate genes underlying porcine reproductive traits, a genome-wide association study (GWAS) was performed in a Duroc pig population. In total, 1067 pigs were genotyped using single-nucleotide polymorphism (SNP) chips, and four reproductive traits, including litter size at birth (LSB), litter weight at birth (LWB), litter size at weaning (LSW), and litter weight at weaning (LWW), were examined. The results showed that 20 potential SNPs reached the level of suggestive significance and were associated with these traits of interest. Several important candidate genes, including TXN2, KCNA1, ENSSSCG00000003546, ZDHHC18, MAP2K6, BICC1, FAM135B, EPHB2, SEMA4D, ST3GAL1, KCTD3, FAM110A, TMEM132D, TBX3, and FAM110A, were identified and might compose the underlying genetic architecture of porcine reproductive traits. These findings help to understand the genetic basis of porcine reproductive traits and provide important information for molecular breeding in pigs.

A genome-wide association study of reproductive traits in a Yorkshire pig population

2018 ◽  
Vol 209 ◽  
pp. 67-72 ◽  
Author(s):  
Md. Rasel Uzzaman ◽  
Jong-Eun Park ◽  
Kyung-Tai Lee ◽  
Eun-Seok Cho ◽  
Bong-Hwan Choi ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Genome Wide Association ◽  
Genome Wide ◽  
A Genome

scholarly journals Genome-wide association study for reproductive traits in a Large White pig population

2018 ◽  
Vol 49 (2) ◽  
pp. 127-131 ◽  
Author(s):  
Y. Wang ◽  
X. Ding ◽  
Z. Tan ◽  
K. Xing ◽  
T. Yang ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Genome Wide Association ◽  
Large White ◽  
Genome Wide ◽  
Large White Pig

Genome‐wide association study of growth traits in Jinghai Yellow chicken hens using SLAF‐seq technology

2015 ◽  
Vol 50 (2) ◽  
pp. 175-176 ◽  
Author(s):  
W. H. Wang ◽  
J. Y. Wang ◽  
T. Zhang ◽  
Y. Wang ◽  
Y. Zhang ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Growth Traits ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Jinghai Yellow Chicken

scholarly journals Genome-wide association study using haplotype alleles for the evaluation of reproductive traits in Nelore cattle

PLoS ONE ◽  
2018 ◽  
Vol 13 (8) ◽  
pp. e0201876 ◽  
Author(s):  
André Vieira do Nascimento ◽  
Ândrea Renata da Silva Romero ◽  
Yuri Tani Utsunomiya ◽  
Adam Taiti Harth Utsunomiya ◽  
Diercles Francisco Cardoso ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Genome Wide Association ◽  
Genome Wide ◽  
Nelore Cattle

scholarly journals Genome-wide association study of reproductive traits in Nellore heifers using Bayesian inference

2015 ◽  
Vol 47 (1) ◽  
Author(s):  
Raphael B. Costa ◽  
Gregório MF Camargo ◽  
Iara DPS Diaz ◽  
Natalia Irano ◽  
Marina M. Dias ◽  
...  
Keyword(s):  
Bayesian Inference ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Genome Wide Association ◽  
Genome Wide

scholarly journals Erratum to: Genome-wide association study of reproductive traits in Nellore heifers using Bayesian inference

2015 ◽  
Vol 47 (1) ◽  
Author(s):  
Raphael B. Costa ◽  
Gregório MF Camargo ◽  
Iara DPS Diaz ◽  
Natalia Irano ◽  
Marina M. Dias ◽  
...  
Keyword(s):  
Bayesian Inference ◽  
Association Study ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Genome Wide Association ◽  
Genome Wide

Genome-wide association study of four composite reproductive traits in Iranian fat-tailed sheep

2019 ◽  
Vol 31 (6) ◽  
pp. 1127 ◽  
Author(s):  
R. Abdoli ◽  
S. Z. Mirhoseini ◽  
N. Ghavi Hossein-Zadeh ◽  
P. Zamani ◽  
M. H. Ferdosi ◽  
...  
Keyword(s):  
Association Study ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Genome Wide Association ◽  
Nucleotide Polymorphisms ◽  
Litter Weight ◽  
Genome Wide ◽  
A Genome ◽  
C Subunit ◽  
Estimated Breeding Values

Composite reproductive traits are a combination of growth and reproductive traits. They have the advantage of being better attuned to the market drivers since producers are paid on a per kilogram basis and not on a per head basis. In this study, 124 Lori­­–Bakhtiari ewes were genotyped using the medium-density Illumina Ovine SNP50 array. A genome-wide association study was performed on estimated breeding values of four composite reproductive traits and genetic parameters were also estimated. The traits were litter mean weight at birth, litter mean weight at weaning, total litter weight at birth and total litter weight at weaning. Several suggestive and associated single nucleotide polymorphisms (SNPs) were identified. Neighbouring the top SNPs there were five genes, inhibin β E subunit (INHBE), inhibin β C subunit (INHBC), testis expressed 12 (TEX12), β-carotene oxygenase 2 (BCO2) and WD Repeat Domain 70 (WDR70) identified as possible candidate genes for composite reproductive traits of the Lori–Bakhtiari sheep. These genes are in pathways known to be relevant to fertility and growth characteristics. The results provide new information for the functional annotation of genes associated with fertility traits and add new evidence towards a consensus of quantitative trait loci associated with reproductive traits in sheep.

scholarly journals A genome-wide association study for prolificacy in three Polish sheep breeds

2021 ◽  
Author(s):  
Grzegorz Smołucha ◽  
Artur Gurgul ◽  
Igor Jasielczuk ◽  
Aldona Kawęcka ◽  
Anna Miksza-Cybulska
Keyword(s):  
Association Study ◽  
Litter Size ◽  
Functional Data ◽  
Genome Wide Association Study ◽  
Reproductive Traits ◽  
Phenotypic Selection ◽  
Genome Wide Association ◽  
Sheep Breeds ◽  
Genome Wide ◽  
A Genome

AbstractReproductive traits (especially litter size) are usually characterized by low heritability, and thus, phenotypic selection is often ineffective and slow. In order to improve fertility characteristics such as ovulation rate and litter size, it seems more effective to select breeding animals based on their genotype. The aim of the study was to use genome-wide association study (GWAS) in three sheep breeds to identify the genetic variants affecting the litter size in sheep. The study allowed us to identify one genome-wide significant SNP (rs402032081—located in ephrin type-A receptor 6, EPHA6) showing an association with litter size in Polish Mountain Sheep. We suggest that the EPHA6 gene can be a candidate gene for prolificacy trait in selected breeds of sheep; however, it needs further functional data for validation.

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