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904P ACCURACY: A phase II trial of AL101, a selective gamma secretase inhibitor, in subjects with recurrent/metastatic (R/M) adenoid cystic carcinoma (ACC) harboring Notch activating mutations (Notchmut): Results of 6-mg cohort
Annals of Oncology
◽
10.1016/j.annonc.2021.08.1314
◽
2021
◽
Vol 32
◽
pp. S803-S804
Author(s):
A.L. Ho
◽
D.W. Bowles
◽
C. Even
◽
D. Hao
◽
H. Kang
◽
...
Keyword(s):
Adenoid Cystic Carcinoma
◽
Phase Ii
◽
Phase Ii Trial
◽
Gamma Secretase
◽
Activating Mutations
◽
Adenoid Cystic
◽
Secretase Inhibitor
◽
Gamma Secretase Inhibitor
Download Full-text
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Cited By
References
919MO ACCURACY a phase II trial of AL101, a selective gamma secretase inhibitor, in subjects with recurrent/metastatic (R/M) adenoid cystic carcinoma (ACC) harboring Notch activating mutations (Notchmut)
Annals of Oncology
◽
10.1016/j.annonc.2020.08.1034
◽
2020
◽
Vol 31
◽
pp. S663
Author(s):
R. Ferrarotto
◽
L.J. Wirth
◽
J. Muzaffar
◽
C.P. Rodriguez
◽
B. Xia
◽
...
Keyword(s):
Adenoid Cystic Carcinoma
◽
Phase Ii
◽
Phase Ii Trial
◽
Gamma Secretase
◽
Activating Mutations
◽
Adenoid Cystic
◽
Secretase Inhibitor
◽
Gamma Secretase Inhibitor
Download Full-text
Response of NOTCH1-Activated Tracheal Adenoid Cystic Carcinoma to the Gamma Secretase Inhibitor Nirogacestat
JCO Precision Oncology
◽
10.1200/po.21.00228
◽
2021
◽
pp. 1579-1583
Author(s):
Rosalind Kieran
◽
Bruno H. R. de Paula
◽
Michael Hubank
◽
Allanah Barker
◽
Anna L. Paterson
◽
...
Keyword(s):
Adenoid Cystic Carcinoma
◽
Gamma Secretase
◽
Adenoid Cystic
◽
Secretase Inhibitor
◽
Gamma Secretase Inhibitor
Download Full-text
A phase II study of single-agent RO4929097, a gamma-secretase inhibitor of Notch signaling, in patients with recurrent platinum-resistant epithelial ovarian cancer: A study of the Princess Margaret, Chicago and California phase II consortia
Gynecologic Oncology
◽
10.1016/j.ygyno.2015.03.005
◽
2015
◽
Vol 137
(2)
◽
pp. 216-222
◽
Cited By ~ 32
Author(s):
Ivan Diaz-Padilla
◽
Michelle K. Wilson
◽
Blaise A. Clarke
◽
Hal W. Hirte
◽
Stephen A. Welch
◽
...
Keyword(s):
Ovarian Cancer
◽
Epithelial Ovarian Cancer
◽
Notch Signaling
◽
Phase Ii
◽
Phase Ii Study
◽
Single Agent
◽
Gamma Secretase
◽
Platinum Resistant
◽
Secretase Inhibitor
◽
Gamma Secretase Inhibitor
Download Full-text
Phase II trial of doxorubicin (D) and bortezomib (B) in patients with incurable adenoid cystic carcinoma of the head and neck.
Journal of Clinical Oncology
◽
10.1200/jco.2010.28.15_suppl.tps271
◽
2010
◽
Vol 28
(15_suppl)
◽
pp. TPS271-TPS271
Author(s):
A. P. Kotsakis
◽
W. E. Gooding
◽
A. Argiris
Keyword(s):
Adenoid Cystic Carcinoma
◽
Head And Neck
◽
Phase Ii
◽
Phase Ii Trial
◽
Adenoid Cystic
Download Full-text
Alliance A091104: A phase II trial of MK-2206 in patients (pts) with progressive, recurrent/metastatic adenoid cystic carcinoma.
Journal of Clinical Oncology
◽
10.1200/jco.2015.33.15_suppl.6039
◽
2015
◽
Vol 33
(15_suppl)
◽
pp. 6039-6039
◽
Cited By ~ 3
Author(s):
Alan Loh Ho
◽
Nathan R. Foster
◽
Jeffrey P. Meyers
◽
Shyamprasad Deraje Vasudeva
◽
Nora Katabi
◽
...
Keyword(s):
Adenoid Cystic Carcinoma
◽
Phase Ii
◽
Phase Ii Trial
◽
Adenoid Cystic
Download Full-text
Phase II trial of dasatinib for recurrent or metastatic c-KIT expressing adenoid cystic carcinoma and for nonadenoid cystic malignant salivary tumors
Annals of Oncology
◽
10.1093/annonc/mdv537
◽
2016
◽
Vol 27
(2)
◽
pp. 318-323
◽
Cited By ~ 33
Author(s):
S.J. Wong
◽
T. Karrison
◽
D.N. Hayes
◽
M.S. Kies
◽
K.J. Cullen
◽
...
Keyword(s):
Adenoid Cystic Carcinoma
◽
Phase Ii
◽
Phase Ii Trial
◽
Adenoid Cystic
Download Full-text
Abstract CT165: A phase II trial of all-trans retinoic acid (ATRA) in advanced adenoid cystic carcinoma
10.1158/1538-7445.am2021-ct165
◽
2021
◽
Author(s):
Glenn J. Hanna
◽
Anne O'Neill
◽
Jennifer M. Cutler
◽
Michelle Flynn
◽
Tushara Vijaykumar
◽
...
Keyword(s):
Retinoic Acid
◽
Adenoid Cystic Carcinoma
◽
Phase Ii
◽
Phase Ii Trial
◽
Adenoid Cystic
◽
Trans Retinoic Acid
◽
All Trans Retinoic Acid
Download Full-text
P1-343: A phase II study of the gamma-secretase inhibitor avagacestat (BMS-708163) in predementia Alzheimer's disease
Alzheimer s & Dementia
◽
10.1016/j.jalz.2013.05.569
◽
2013
◽
Vol 9
◽
pp. P283-P283
◽
Cited By ~ 8
Author(s):
Vlad Coric
◽
Stephen Salloway
◽
Christopher van Dyck
◽
Wendy Kerselaers
◽
Stephen Kaplita
◽
...
Keyword(s):
Alzheimer’S Disease
◽
Alzheimer's Disease
◽
Phase Ii
◽
Phase Ii Study
◽
Gamma Secretase
◽
Secretase Inhibitor
◽
Gamma Secretase Inhibitor
Download Full-text
Local Control following Combination Hypofractionated Radiotherapy and Pembrolizumab in A Phase II Trial of Recurrent or Metastatic Adenoid Cystic Carcinoma Patients
International Journal of Radiation Oncology*Biology*Physics
◽
10.1016/j.ijrobp.2019.06.1700
◽
2019
◽
Vol 105
(1)
◽
pp. E363
Author(s):
A. Bang
◽
U. Mahmood
◽
Y.H. Chen
◽
R.H. Mak
◽
J. Lorch
◽
...
Keyword(s):
Adenoid Cystic Carcinoma
◽
Phase Ii
◽
Local Control
◽
Phase Ii Trial
◽
Hypofractionated Radiotherapy
◽
Adenoid Cystic
Download Full-text
57 Local Control Following Combination Hypofractionated Radiotherapy and Pembrolizumab in a Phase II Trial of Recurrent or Metastatic Adenoid Cystic Carcinoma Patients
Radiotherapy and Oncology
◽
10.1016/s0167-8140(19)33345-6
◽
2019
◽
Vol 139
◽
pp. S26-S27
Author(s):
Andrew Bang
◽
Umair Mahmood
◽
Yu-Hui Chen
◽
Raymond H. Mak
◽
Jochen H. Lorch
◽
...
Keyword(s):
Adenoid Cystic Carcinoma
◽
Phase Ii
◽
Local Control
◽
Phase Ii Trial
◽
Hypofractionated Radiotherapy
◽
Adenoid Cystic
Download Full-text
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