scholarly journals Dentin sialophosphoprotein and dentin matrix protein-1: Two highly phosphorylated proteins in mineralized tissues

2012 ◽  
Vol 57 (9) ◽  
pp. 1165-1175 ◽  
Author(s):  
Shigeki Suzuki ◽  
Naoto Haruyama ◽  
Fusanori Nishimura ◽  
Ashok B. Kulkarni
2008 ◽  
Vol 189 (1-4) ◽  
pp. 186-191 ◽  
Author(s):  
Izabela Maciejewska ◽  
Disheng Qin ◽  
Bingzhen Huang ◽  
Yao Sun ◽  
Gabrielle Mues ◽  
...  

2006 ◽  
Vol 281 (28) ◽  
pp. 19064-19071 ◽  
Author(s):  
Karthikeyan Narayanan ◽  
Sivakumar Gajjeraman ◽  
Amsaveni Ramachandran ◽  
Jianjun Hao ◽  
Anne George

2009 ◽  
Vol 20 (5) ◽  
pp. 365-369 ◽  
Author(s):  
Elizabeth Ferreira Martinez ◽  
Luciana Alves Herdy da Silva ◽  
Cristiane Furuse ◽  
Ney Soares de Araújo ◽  
Vera Cavalcanti de Araújo

Dentin matrix protein 1 (DMP1) is an acidic phosphoprotein that plays an important role in mineralized tissue formation by initiation of nucleation and modulation of mineral phase morphology. The purpose of the present study was to examine the immunoexpression of DMP1 in tooth germs of 7 human fetuses at different gestational ages (14, 16, 19, 20, 21, 23 and 24 weeks) comparing with completed tooth formation erupted teeth. The results showed the presence of DMP1 in the dental lamina, as well as in the cells of the external epithelium, stellate reticulum and stratum intermedium of the enamel organ. However, in the internal dental epithelium, cervical loop region and dental papilla some cells have not labeled for DMP1. In the crown stage, DMP1 was expressed in the ameloblast and odontoblast layer, as well as in the dentinal tubules of coronal dentin near the odontoblast area. Erupted teeth with complete tooth formation exhibited immunolabeling for DMP1 only in the dentinal tubules mainly close to the dental pulp. No staining was observed in the enamel, predentin or dental pulp matrix. DMP1 is present in all developing dental structures (dental lamina, enamel organ, dental papilla) presenting few immunoexpression variations, with no staining in mineralized enamel and dentin.


2002 ◽  
Vol 43 (2) ◽  
pp. 365-371 ◽  
Author(s):  
Karthikeyan Narayanan ◽  
Amsaveni Ramachandran ◽  
Jianjun Hao ◽  
Anne George

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