Three Distomolar in Single Patient: A Unique Case Report

Supernumerary teeth are defined as those in addition to the normal series of deciduous or permanent dentition. Supernumerary teeth are more prevalent among males and in the permanent dentition. The exact etiology of supernumerary teeth is unknown, they may occur anywhere in the oral cavity. They may appear as a single tooth or multiple teeth, unilaterally or bilaterally, erupted or impacted in maxilla or both jaws. Fourth molars, also called distomolars, are a variant in shape and number appearing as alterations during odontogenesis. They can be eumorphic or dismorphic, single or multiple, erupted or impacted, unilateral or bilateral, and can appear in both jaws. They are of unknown etiology, but there are several theories to justify these tooth alterations such as dental lamina duplication, its horizontal proliferation or its hyperactivity. Hereby, we are presenting a unique case report of presence of three distomolars in a single patient at maxillary left side and mandibular right and left side.

Odontogenic Keratocyst in Anterior Mandible: A Case Report

Odontogenic Keratocyst (OKC) is a non-inflammatory developmental odontogenic cyst arises from cell rest of the dental lamina and most commonly occurs in the posterior of the mandible. OKC may be detected in patients of various age groups, from infants to seniors, and usually occurs in the third and fourth decades of the patient’s life. Female to male prevalence is 2:1 respectively. Mandible makes up 60% to 80% of cases and shows a specific tendency to involve the ramus and posterior area. Detection of OKC through clinical exams and radiography is to be suspected, and thus, confirmation via histopathology is needed. This study describes the occurrence of this lesion in a rare location in a 36 years old female patient.

Odontogenic keratocyst: diagnostic characteristics and conservative surgical treatment

Keratocyst is a benign odontogenic lesion with aggressive behavior, probably derived from the dental lamina. It is frequently located in the posterior part of the mandibular bone in the area of ​​the third molar, mandibular angle and can progress towards the ramus and the body, presenting a direct association with retained dental organs. There is a wide variety of techniques for the treatment of this lesion, such as decompression, marsupialization, enucleation, and en bloc resection, as well as the combination of these with adjuvant methods. The interest in this lesion stems from its high recurrence rate, which is estimated to be 20-30% in the general population, however, at present the use of conservative treatments such as marsupialization and decompression has been chosen. demonstrated greater effectiveness and less recurrence. This is why after treating the lesions it is important to give a long-term follow-up. The objective of the publication is to present the report of a clinical case of a 21-year-old male patient with a diagnosis of odontogenic keratocyst treated with a decompression technique for five months for subsequent surgical enucleation. It has been proven that decompression treatment followed by enucleation and accompanied by adjuvant methods is an adequate therapeutic management for keratocysts as it demonstrates its lower rate of recurrence and its noble behavior with neighboring vital structures. However, in all cases, regular monitoring should be carried out to prevent recurrence of the lesion.

Expect the unexpected – A rare case of Orthokeratinized Odontogenic Cyst and its surgical management

Orthokeratinized Odontogenic Cyst (OOC) is a rare, developmental odontogenic cyst of the dental lamina. It was initially defined as the uncommon orthokeratinized variant of the Odontogenic Keratocyst (OKC), until the World Health Organization’s (WHO’s) classification in 2005 and 2017, where it was separated from the Keratocystic Odontogenic Tumor (KCOT) and has been included as a separate entity from the category of developmental odontogenic cysts respectively. It presents as a unilocular radiolucent lesion involving the posterior mandible and is frequently related to impacted teeth, often similar to other odontogenic cysts. Due to low local aggressiveness and less proliferative activity, it has to be differentiated from the other cysts in terms of surgical management. Here we report a rare case of OOC involving the maxilla along with an impacted canine and discuss the surgical management and why a secondary surgical intervention is unnecessary.

Odontogenic Keratocyst in a 9-Month-Old Patient: A Case Report

Odontogenic Keratocyst (OKC) is a benign, intraosseous, odontogenic cyst which originates from the basal cells of overlying epithelium or from the dental lamina remnants. Clinically, they are presented as asymptomatic swellings, although can sometimes be associated with pain. Growth of an OKC leads to expansion and destruction of bone as it infiltrates the tissue around it. It is commonly seen in males between the second and fourth decades of life. The aim of this study is to report on the clinicopathological characteristics of an odontogenic keratocyst in a 9-month-old female patient and posterior rehabilitation with a removable maxillary expander.

Multiple Odontogenic Keratocysts in a Non-syndromic Young Patient: An Unusual Case Report

Odontogenic keratocyst (OKC) is a benign intraosseous lesion with invasive and aggressive behavior. It comprises approximately 2-21.8% of all jaw cysts. Odontogenic keratocysts (OKCs) are believed to arise from remnants of the dental lamina most common site in the molar ramus area. OKCs have a specific histopathologic appearance and are found to be locally aggressive and have a high recurrence rate, thus requires close long-term follow-up. OKCs are one component of the Gorlin-Goltz syndrome and all patients with multiple OKCs should be evaluated for this syndrome. In this paper, we present a case of a 13-year old non-syndromic female patient with multiple OKCs located at symphysis and bilateral mandibular angle region who was treated surgically with no obvious post-operative complications during follow-up period.

Tooth Removal in the Leopard Gecko and the de novo Formation of Replacement Teeth

Many reptiles are able to continuously replace their teeth through life, an ability attributed to the existence of epithelial stem cells. Tooth replacement occurs in a spatially and temporally regulated manner, suggesting the involvement of diffusible factors, potentially over long distances. Here, we locally disrupted tooth replacement in the leopard gecko (Eublepharis macularius) and followed the recovery of the dentition. We looked at the effects on local patterning and functionally tested whether putative epithelial stem cells can give rise to multiple cell types in the enamel organs of new teeth. Second generation teeth with enamel and dentine were removed from adult geckos. The dental lamina was either left intact or disrupted in order to interfere with local patterning cues. The dentition began to reform by 1 month and was nearly recovered by 2–3 months as shown in μCT scans and eruption of teeth labeled with fluorescent markers. Microscopic analysis showed that the dental lamina was fully healed by 1 month. The deepest parts of the dental lamina retained odontogenic identity as shown by PITX2 staining. A pulse-chase was carried out to label cells that were stimulated to enter the cell cycle and then would carry BrdU forward into subsequent tooth generations. Initially we labeled 70–78% of PCNA cells with BrdU. After a 1-month chase, the percentage of BrdU + PCNA labeled cells in the dental lamina had dropped to 10%, consistent with the dilution of the label. There was also a population of single, BrdU-labeled cells present up to 2 months post surgery. These BrdU-labeled cells were almost entirely located in the dental lamina and were the likely progenitor/stem cells because they had not entered the cell cycle. In contrast fragmented BrdU was seen in the PCNA-positive, proliferating enamel organs. Homeostasis and recovery of the gecko dentition was therefore mediated by a stable population of epithelial stem cells in the dental lamina.

A Case of Ameloblastic Fibrodentinoma in the Posterior Maxilla

Ameloblastic fibrodentinoma (AFD) is a rare tumor with an incidence rate of less than 1%. When lesion with the histomorphology of ameloblastic fibroma(AF), which is true neoplasms, form dysplastic dentin, and had been referred to as AFD. It histologically consists of odontogenic ectomesenchyme resembling the dental papilla, epithelial strands, and nests resembling dental lamina and enamel organ with dentin formation. Although newly categorized as an odontoma by the WHO in 2017, this lesion was previously referred to as a rare odontogenic tumor by the WHO in 2005. Objective: We aim to summarize our case with other previous case reports considered to be equivalent to the conventional WHO classification of AFD. Case Report: An 8-year-old girl presented to our hospital complaining of delayed eruption of a tooth. Computed tomography showed an odontoma-like radiopacity in a unilocular radiolucent lesion sized approximately 20 mm. The lesion was extracted under general anesthesia and histopathologically exhibited AFD. Herein, we report a rare case of AFD in the maxilla. Conclusion: Although this lesion deviates from the concept of disease as an odontogenic tumor, it is hoped that clinically sufficient follow-up is required and more similar cases will accumulate as independent tumors, rather than simply being recognized as developmental odontomas

Management of gingival cyst of a newborn: a case report with epidemiological data.

Introduction: Gingival cyst also known as Dental Lamina cyst. They form small nodules or cysts on the alveolar ridge, each up to 2 mm in diameter. They are considered to be due to proliferation of the epithelial rests of Serres but can arise on the lateral aspects of the ridge and the crest. They are considered to be benign lesions which usually are present on the alveolar ridge and are often mistaken as neonatal tooth. Objective: The aim of this case report is to enlist and describe the diagnostic features and management of the gingival cyst of newborn, as these kind of lesions can cause anxiety and fear among the parents. It is important to diagnose these conditions in order to prevent unnecessary surgical interventions and provide adequate care and proper knowledge to the parents. Method: This is a case study of asymptomatic gingival cyst which was present in a newborn at the time of birth on the lower alveolar ridge. Diagnosis of this keratin filled small cystic lesion was made on the basis of clinical history and oral findings. Conclusion: Gingival cyst of infants are transient lesions. No definitive treatment was given but the patient was kept on follow-up for 3 months during which the lesion regressed by itself. Update Dent. Coll. j: 2021; 11 (1): 23-25