Identification of a protein-containing enamel matrix layer which bridges with the dentine–enamel junction of adult human teeth

The matrix of fluorotic enamel is studied by S.E.M. and histochemically by light microscopy. Observations are made on fluorotic human teeth and on rat incisors in which fluorosis has been produced by daily injections of NaF. The enamel sheaths appear enlarged and irregular, rich in stainable proteins, while glycocomponents of the matrix are less dense. A relationship is suggested between those alterations and the further irregular pattern of mineralization of fluorotic enamel.

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Presence of an enamel matrix protein derivative on human teeth following periodontal surgery

Clinical Oral Investigations ◽

10.1007/s00784-002-0171-6 ◽

2002 ◽

Vol 6 (3) ◽

pp. 183-187 ◽

Cited By ~ 48

Author(s):

Anton Sculean ◽

Péter Windisch ◽

Tibor Keglevich ◽

Beata Fabi ◽

Eva Lundgren ◽

...

Keyword(s):

Matrix Protein ◽

Enamel Matrix ◽

Periodontal Surgery ◽

Human Teeth ◽

Enamel Matrix Protein

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Proteomic analysis of dentin-enamel junction and adjacent protein-containing enamel matrix layer of healthy human molar teeth

European Journal Of Oral Sciences ◽

10.1111/eos.12594 ◽

2018 ◽

Vol 127 (2) ◽

pp. 112-121 ◽

Cited By ~ 5

Author(s):

Michal Jágr ◽

Peter Ergang ◽

Statis Pataridis ◽

Marta Kolrosová ◽

Martin Bartoš ◽

...

Keyword(s):

Proteomic Analysis ◽

Enamel Matrix ◽

Healthy Human ◽

Matrix Layer ◽

Molar Teeth

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Effects of enamel matrix proteins on tissue formation along the roots of human teeth

Journal of Periodontal Research ◽

10.1111/j.1600-0765.2005.00785.x ◽

2005 ◽

Vol 40 (2) ◽

pp. 158-167 ◽

Cited By ~ 52

Author(s):

Dieter D. Bosshardt ◽

Anton Sculean ◽

Peter Windisch ◽

Bjarni E. Pjetursson ◽

Niklaus P. Lang

Keyword(s):

Matrix Proteins ◽

Tissue Formation ◽

Enamel Matrix ◽

Enamel Matrix Proteins ◽

Human Teeth

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Dentino-Enamel Cuticle Present in Adult Human Teeth

Journal of Dental Research ◽

10.1177/00220345490280060601 ◽

1949 ◽

Vol 28 (6) ◽

pp. 565-568 ◽

Cited By ~ 3

Author(s):

Victorino G. Villa

Keyword(s):

Human Teeth ◽

Adult Human

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Are there structural alterations in the enamel organ of offspring of rats with alloxan-induced diabetes mellitus?

Brazilian Dental Journal ◽

10.1590/s0103-64402003000300004 ◽

2003 ◽

Vol 14 (3) ◽

pp. 162-167 ◽

Cited By ~ 6

Author(s):

Yara Teresinha Corrêa Silva-Sousa ◽

Luiz Cesar Peres ◽

Milton César Foss

Keyword(s):

Structural Defects ◽

Deciduous Teeth ◽

Enamel Organ ◽

Developmental Defect ◽

Enamel Matrix ◽

Enamel Hypoplasia ◽

Human Teeth ◽

Structural Alterations ◽

Future Studies ◽

Diabetic Mothers

Enamel hypoplasia is the most common developmental defect of human teeth that may be seen in deciduous teeth of babies born to diabetic women. In the present experimental study, we analyzed the enamel organ of the mandibular incisors of the offspring of rats with alloxan-induced diabetes. By light microscopy, no alterations could be found in the enamel organ of rats born to diabetic mothers compared to normal ones, except in one case. In contrast, significant differences were detected with computer-aided morphometry. In the rats born to treated and untreated diabetic mothers, there was thinning of the enamel matrix and of the ameloblasts and the nuclear area of the latter was smaller. In the rats born to treated diabetic mothers, the nuclei of the ameloblasts were more elliptical and there was enlargement of the interstitial area of the stellate reticulum. These results indicate that there are structural defects in the enamel organ of rats born to mothers with alloxan-induced diabetes which could induce the enamel hypoplasia observed by scanning electron microscopy and which may reflect the metabolic alterations seen in this condition. Future studies are needed to determine whether these effects are transitory or permanent.

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