Association between aldehyde dehydrogenase 2 genetic polymorphism and serum lipids or lipoproteins: A meta-analysis of seven East Asian populations

2010 ◽  
Vol 212 (1) ◽  
pp. 213-216 ◽  
Author(s):  
Pan-Pan Hao ◽  
Li Xue ◽  
Xing-Li Wang ◽  
Yu-Guo Chen ◽  
Jia-Li Wang ◽  
...  
Keyword(s):  
Genetic Polymorphism ◽  
Aldehyde Dehydrogenase ◽  
Serum Lipids ◽  
Meta Analysis ◽  
East Asian ◽  
Aldehyde Dehydrogenase 2 ◽  
Asian Populations

scholarly journals Meta-Analysis of Aldehyde Dehydrogenase 2 Gene Polymorphism and Alzheimer's Disease in East Asians

2011 ◽  
Vol 38 (3) ◽  
pp. 500-506 ◽  
Author(s):  
Pan-Pan Hao ◽  
Yu-Guo Chen ◽  
Jia-Li Wang ◽  
Xing Li Wang ◽  
Yun Zhang
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Aldehyde Dehydrogenase ◽  
Meta Analysis ◽  
East Asian ◽  
Small Sample ◽  
Aldehyde Dehydrogenase 2 ◽  
Cross Sectional ◽  
Asian Populations ◽  
Aldehyde Dehydrogenase 2 Gene

Background:The association of genetic polymorphism of mitochondrial aldehyde dehydrogenase 2 (ALDH2) and Alzheimer's disease (AD) has been controversial and has been investigated only in several small-sample studies. In the present study, we performed a meta-analysis to evaluate the cross-sectional association ofALDH2variants and AD risk in East Asian populations.Methods:Trials were retrieved through MEDLINE, EMBASE, J-STAGE and the China National Knowledge Internet databases (from January 1, 1994 to November 1, 2010) without any restriction on language. Data were abstracted by a standardized protocol.Results:We found four studies of 821AD patients and 1380 healthy controls that qualified for the analysis. The variantALDH2genotype GA/AA was not associated with increased AD risk (odds ratio (OR) = 1.35; 95% confidence interval (CI) = 0.75-2.42; p = 0.32), even after stratification for the status of apolipoprotein E epsilon 4 allele. However, in the subgroup analyses, the association was significant for men (OR = 1.72; 95% CI = 1.10-2.67; p = 0.02).Conclusions:This study adds to the evidence thatALDH2GA/AA genotype increases the risk of AD among East Asian men, although the effect size is moderate.

GSTM1 polymorphism and lung cancer risk among East Asian populations: a meta-analysis

Tumor Biology ◽  
2014 ◽  
Vol 35 (7) ◽  
pp. 6493-6500 ◽  
Author(s):  
Yan Zhao ◽  
Junjie Zeng ◽  
Yanxi Zhang ◽  
Su Lu ◽  
Erjiang Zhao ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Meta Analysis ◽  
East Asian ◽  
Asian Populations ◽  
Gstm1 Polymorphism

scholarly journals East Asian Variant of Aldehyde Dehydrogenase 2 Is Associated With Coronary Spastic Angina

Circulation ◽  
2015 ◽  
Vol 131 (19) ◽  
pp. 1665-1673 ◽  
Author(s):  
Yuji Mizuno ◽  
Eisaku Harada ◽  
Sumio Morita ◽  
Kenji Kinoshita ◽  
Mariko Hayashida ◽  
...  
Keyword(s):  
Aldehyde Dehydrogenase ◽  
East Asian ◽  
Aldehyde Dehydrogenase 2

scholarly journals Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2

2009 ◽  
Vol 9 (S2) ◽  
Author(s):  
Matteo Beretta ◽  
Antonius CF Gorren ◽  
Verena M Wenzl ◽  
Robert Weis ◽  
Michael Russwurm ◽  
...  
Keyword(s):  
Aldehyde Dehydrogenase ◽  
East Asian ◽  
Aldehyde Dehydrogenase 2

scholarly journals Bioactivation of nitroglycerin by the East Asian variant of aldehyde dehydrogenase-2

2009 ◽  
Vol 9 (S1) ◽  
Author(s):  
Matteo Beretta ◽  
Antonius CF Gorren ◽  
M Verena Wenzl ◽  
Robert Weis ◽  
Michael Russwurm ◽  
...  
Keyword(s):  
Aldehyde Dehydrogenase ◽  
East Asian ◽  
Aldehyde Dehydrogenase 2

Aldehyde dehydrogenase 2 polymorphism for development to hepatocellular carcinoma in East Asian alcoholic liver cirrhosis

2015 ◽  
Vol 30 (9) ◽  
pp. 1376-1383 ◽  
Author(s):  
Hiroshi Abe ◽  
Yuta Aida ◽  
Nobuyoshi Seki ◽  
Tomonori Sugita ◽  
Yoichi Tomita ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Liver Cirrhosis ◽  
Aldehyde Dehydrogenase ◽  
East Asian ◽  
Alcoholic Liver Cirrhosis ◽  
Aldehyde Dehydrogenase 2

scholarly journals Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

2012 ◽  
Vol 44 (8) ◽  
pp. 904-909 ◽  
Author(s):  
Yukinori Okada ◽  
◽  
Xueling Sim ◽  
Min Jin Go ◽  
Jer-Yuarn Wu ◽  
...  
Keyword(s):  
Kidney Function ◽  
Meta Analysis ◽  
East Asian ◽  
Asian Populations ◽  
Multiple Loci
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