Contribution of cholesterol-binding motifs in ABCA1, ABCG1 and SR-B1 structure to cellular cholesterol transport

2018 ◽  
Vol 275 ◽  
pp. e169
Author(s):  
A. Dergunov ◽  
E. Savushkin ◽  
L. Dergunova ◽  
D. Litvinov
Keyword(s):  
Cholesterol Transport ◽  
Binding Motifs ◽  
Cellular Cholesterol ◽  
Cholesterol Binding

scholarly journals Cellular Cholesterol Transport and Efflux in Fibroblasts Are Abnormal in Subjects With Familial HDL Deficiency

1999 ◽  
Vol 19 (1) ◽  
pp. 159-169 ◽  
Author(s):  
Michel Marcil ◽  
Lu Yu ◽  
Larbi Krimbou ◽  
Betsie Boucher ◽  
John F. Oram ◽  
...  
Keyword(s):  
Cholesterol Transport ◽  
Cellular Cholesterol

U18666A, an intra-cellular cholesterol transport inhibitor, inhibits dengue virus entry and replication

2012 ◽  
Vol 93 (1) ◽  
pp. 191-198 ◽  
Author(s):  
Mee Kian Poh ◽  
Guanghou Shui ◽  
Xuping Xie ◽  
Pei-Yong Shi ◽  
Markus R. Wenk ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Virus Entry ◽  
Cholesterol Transport ◽  
Cellular Cholesterol ◽  
Transport Inhibitor

scholarly journals Acute Tubular Injury Causes Dysregulation of Cellular Cholesterol Transport Proteins

2003 ◽  
Vol 163 (1) ◽  
pp. 313-320 ◽  
Author(s):  
Richard A. Zager ◽  
Ali C.M. Johnson ◽  
Sherry Y. Hanson ◽  
Vallabh O. Shah
Keyword(s):  
Transport Proteins ◽  
Cholesterol Transport ◽  
Tubular Injury ◽  
Cellular Cholesterol ◽  
Injury Causes

4.P.338 Familial HDL deficiency: A cellular cholesterol transport defect

1997 ◽  
Vol 134 (1-2) ◽  
pp. 367
Author(s):  
J. Genest ◽  
M. Marcil ◽  
L. Yu ◽  
R. Batal ◽  
L. Krimbou ◽  
...  
Keyword(s):  
Cholesterol Transport ◽  
Cellular Cholesterol ◽  
Transport Defect

Update on HDL Receptors and Cellular Cholesterol Transport

2011 ◽  
Vol 13 (3) ◽  
pp. 233-241 ◽  
Author(s):  
Ginny Kellner-Weibel ◽  
Margarita de la Llera-Moya
Keyword(s):  
Cholesterol Transport ◽  
Cellular Cholesterol

Akt activation increases cellular cholesterol by promoting the proteasomal degradation of Niemann–Pick C1

2015 ◽  
Vol 471 (2) ◽  
pp. 243-253 ◽  
Author(s):  
Ximing Du ◽  
Yuxi Zhang ◽  
Sae Rom Jo ◽  
Xiaoyun Liu ◽  
Yanfei Qi ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Free Cholesterol ◽  
Cell Signalling ◽  
Proteasomal Degradation ◽  
Active Cell ◽  
Cholesterol Transport ◽  
Cellular Cholesterol ◽  
Akt Activation ◽  
Niemann Pick ◽  
Cell Signalling Pathway

The present study shows that a protein required for proper cholesterol transport in cells is degraded by an active cell signalling pathway. The observations provide new insights into why certain cancer cells have high levels of free cholesterol.

Mechanisms for Cellular Cholesterol Transport: Defects and Human Disease

2006 ◽  
Vol 86 (4) ◽  
pp. 1237-1261 ◽  
Author(s):  
Elina Ikonen
Keyword(s):  
Mouse Models ◽  
Human Disease ◽  
Human Diseases ◽  
Cholesterol Transport ◽  
Cholesterol Trafficking ◽  
Cellular Cholesterol ◽  
Intracellular Cholesterol

This review summarizes the mechanisms of cellular cholesterol transport and monogenic human diseases caused by defects in intracellular cholesterol processing. In addition, selected mouse models of disturbed cholesterol trafficking are discussed. Current pharmacological strategies to prevent atherosclerosis are largely based on altering cellular cholesterol balance and are introduced in this context. Finally, because of the organizing potential of cholesterol in membranes, disturbances in cellular cholesterol transport have implications for a wide variety of human diseases, of which selected examples are given.

Significance of Cholesterol-Binding Motifs in ABCA1, ABCG1, and SR-B1 Structure

2018 ◽  
Vol 252 (1) ◽  
pp. 41-60 ◽  
Author(s):  
Alexander D. Dergunov ◽  
Eugeny V. Savushkin ◽  
Liudmila V. Dergunova ◽  
Dmitry Y. Litvinov
Keyword(s):  
Binding Motifs ◽  
Cholesterol Binding
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