Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics

Peizhong Mao; P. Hemachandra Reddy

doi:10.1016/j.bbadis.2011.08.005

Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ◽

10.1016/j.bbadis.2011.08.005 ◽

2011 ◽

Vol 1812 (11) ◽

pp. 1359-1370 ◽

Cited By ~ 154

Author(s):

Peizhong Mao ◽

P. Hemachandra Reddy

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Dna Damage ◽

Early Intervention ◽

Mitochondrial Dysfunction ◽

Amyloid Beta ◽

Oxidative Dna Damage

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Molecular pathophysiology of impaired glucose metabolism, mitochondrial dysfunction, and oxidative DNA damage in Alzheimer's disease brain

Mechanisms of Ageing and Development ◽

10.1016/j.mad.2016.05.005 ◽

2017 ◽

Vol 161 ◽

pp. 95-104 ◽

Cited By ~ 44

Author(s):

Nona Abolhassani ◽

Julio Leon ◽

Zijing Sheng ◽

Sugako Oka ◽

Hideomi Hamasaki ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Dna Damage ◽

Glucose Metabolism ◽

Mitochondrial Dysfunction ◽

Oxidative Dna Damage ◽

Impaired Glucose Metabolism ◽

Molecular Pathophysiology

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Faculty Opinions recommendation of Detection of oxidative DNA damage in lymphocytes of patients with Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021919.247786 ◽

2004 ◽

Author(s):

George Perry

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Dna Damage ◽

Oxidative Dna Damage

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Amyloid Beta Mediated Mitochondrial Dysfunction in Alzheimer's disease: A Mini Review.

Journal of Current Pharma Research ◽

10.33786/jcpr.2019.v09i03.017 ◽

2019 ◽

Vol 9 (3) ◽

pp. 2981-2990

Author(s):

Vivek Sharma . ◽

Priyanka Nagu . ◽

Raneev Thakur . ◽

Pankaj Sharma . ◽

Harish Kumar .

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mitochondrial Dysfunction ◽

Amyloid Beta

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Levels of reduced and oxidized coenzyme Q-10 and 8-hydroxy-2′-deoxyguanosine in the CSF of patients with Alzheimer’s disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process

Journal of Neurology ◽

10.1007/s00415-009-5333-x ◽

2009 ◽

Vol 257 (3) ◽

pp. 399-404 ◽

Cited By ~ 37

Author(s):

Chiaki Isobe ◽

Takashi Abe ◽

Yasuo Terayama

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Dna Damage ◽

Oxidative Damage ◽

Oxidative Dna Damage ◽

Coenzyme Q ◽

Neurodegenerative Process ◽

Mitochondrial Oxidative Damage

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Expression and Polymorphisms of Gene 8-Oxoguanine Glycosylase 1 and the Level of Oxidative DNA Damage in Peripheral Blood Lymphocytes of Patients with Alzheimer's Disease

DNA and Cell Biology ◽

10.1089/dna.2009.0926 ◽

2009 ◽

Vol 28 (11) ◽

pp. 579-588 ◽

Cited By ~ 28

Author(s):

Jolanta Dorszewska ◽

Bartosz Kempisty ◽

Joanna Jaroszewska-Kolecka ◽

Agata Różycka ◽

Jolanta Florczak ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Dna Damage ◽

Peripheral Blood ◽

Oxidative Dna Damage ◽

Peripheral Blood Lymphocytes ◽

Blood Lymphocytes ◽

Oxoguanine Glycosylase 1

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Possible role of amyloid-beta, adenine nucleotide translocase and cyclophilin-D interaction in mitochondrial dysfunction of Alzheimer's disease

Bioinformation ◽

10.6026/97320630003440 ◽

2009 ◽

Vol 3 (10) ◽

pp. 440-445 ◽

Cited By ~ 32

Author(s):

Prabhakar Singh ◽

Shubhankar Suman ◽

Sudhir Chandna ◽

Taposh Kumar Das

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mitochondrial Dysfunction ◽

Amyloid Beta ◽

Adenine Nucleotide ◽

Adenine Nucleotide Translocase ◽

Cyclophilin D

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Abnormal interaction of VDAC1 with amyloid beta and phosphorylated tau causes mitochondrial dysfunction in Alzheimer's disease

Human Molecular Genetics ◽

10.1093/hmg/dds360 ◽

2012 ◽

Vol 21 (23) ◽

pp. 5131-5146 ◽

Cited By ~ 129

Author(s):

M. Manczak ◽

P. H. Reddy

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mitochondrial Dysfunction ◽

Amyloid Beta ◽

Phosphorylated Tau

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From Mitochondrial Dysfunction to Amyloid Beta Formation: Novel Insights into the Pathogenesis of Alzheimer’s Disease

Molecular Neurobiology ◽

10.1007/s12035-012-8307-4 ◽

2012 ◽

Vol 46 (1) ◽

pp. 186-193 ◽

Cited By ~ 93

Author(s):

Kristina Leuner ◽

Walter E. Müller ◽

Andreas S. Reichert

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mitochondrial Dysfunction ◽

Amyloid Beta

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Levels of reduced and oxidized coenzyme Q-10 and 8-hydroxy-2'-deoxyguanosine in the CSF of patients with Alzheimer's disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process

Yearbook of Neurology and Neurosurgery ◽

10.1016/s0513-5117(10)79336-4 ◽

2010 ◽

Vol 2010 ◽

pp. 11-12

Author(s):

J.P. Blass

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Dna Damage ◽

Oxidative Damage ◽

Oxidative Dna Damage ◽

Coenzyme Q ◽

Neurodegenerative Process ◽

Mitochondrial Oxidative Damage

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An Epigenetic Model for Susceptibility to Oxidative DNA Damage in the Aging Brain and Alzheimer’s Disease

Aging and Age-Related Disorders ◽

10.1007/978-1-60761-602-3_22 ◽

2010 ◽

pp. 439-453

Author(s):

Nasser H. Zawia ◽

Fernando Cardozo-Pelaez

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Dna Damage ◽

Oxidative Dna Damage ◽

Aging Brain

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