Both serotonergic and noradrenergic systems modulate the development of tolerance to chronic stress in rats with lesions of the serotonergic neurons of the median raphe nucleus

2019 ◽  
Vol 357-358 ◽  
pp. 39-47 ◽  
Author(s):  
A.C. Pereira ◽  
M.C. Carvalho ◽  
C.M. Padovan
Keyword(s):  
Chronic Stress ◽  
Raphe Nucleus ◽  
Median Raphe ◽  
Median Raphe Nucleus ◽  
Serotonergic Neurons ◽  
Median Raphé ◽  
Development Of Tolerance

Does serotonin play a role in entrance into hibernation?

1986 ◽  
Vol 251 (4) ◽  
pp. R755-R761 ◽  
Author(s):  
B. Canguilhem ◽  
J. L. Miro ◽  
E. Kempf ◽  
P. Schmitt
Keyword(s):  
Anterior Part ◽  
Raphe Nucleus ◽  
Median Raphe ◽  
Median Raphe Nucleus ◽  
Serotonergic Neurons ◽  
Electrolytic Lesions ◽  
Small Parts ◽  
The Brain ◽  
Median Raphé

To study the role of brain serotonin in entrance into hibernation, intraventricular injections of 5,7-dihydroxytryptamine, electrolytic lesions of small parts of the median raphe nucleus, and chemical lesions of the same nucleus were undertaken on the European hamster in winter. All the lesions led to a variable decrease of serotonin levels in all parts of the brain areas examined. However, hibernation was suppressed only in those animals whose serotonergic neurons were destroyed in a small anterior part of the median raphe nucleus. Electrolytic lesions as well as chemical lesions in the other parts of the median raphe nucleus or the 5,7-dihydroxytryptamine injections into lateral ventricles do not prevent hibernation. These data suggest that in the European hamster only a specific group of serotonergic neurons of the median raphe nucleus are involved in the process of entrance into hibernation.

scholarly journals Effect of xanthone from Kielmeyera coriacea stems on serotonergic neurons of the median raphe nucleus

Phytomedicine ◽  
2010 ◽  
Vol 17 (3-4) ◽  
pp. 274-278 ◽  
Author(s):  
V.R. Sela ◽  
I. Hattanda ◽  
C.M. Albrecht ◽  
C.B. De Almeida ◽  
S. Obici ◽  
...  
Keyword(s):  
Raphe Nucleus ◽  
Median Raphe ◽  
Median Raphe Nucleus ◽  
Serotonergic Neurons ◽  
Kielmeyera Coriacea ◽  
Median Raphé
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