The novel histone deacetylase inhibitor BL1521 inhibits proliferation and induces apoptosis in neuroblastoma cells

2004 ◽  
Vol 68 (7) ◽  
pp. 1279-1288 ◽  
Author(s):  
Annemieke J.M. de Ruijter ◽  
Stephan Kemp ◽  
Gertjan Kramer ◽  
Rutger J. Meinsma ◽  
Judith O. Kaufmann ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Neuroblastoma Cells ◽  
The Novel ◽  
Deacetylase Inhibitor

Apoptotic effects of the novel histone deacetylase inhibitor BML-210 on HeLa cells

Biologija ◽  
2008 ◽  
Vol 54 (3) ◽  
pp. 217-220
Author(s):  
V. V. Borutinskaite ◽  
J. Savickiene ◽  
R. Navakauskiene
Keyword(s):  
Histone Deacetylase ◽  
Hela Cells ◽  
Histone Deacetylase Inhibitor ◽  
The Novel ◽  
Deacetylase Inhibitor ◽  
Apoptotic Effects

Abstract 799: The novel histone deacetylase inhibitor pracinostat is an effective anti-lymphoma agent

2018 ◽  
Author(s):  
Afua A. Mensah ◽  
Filippo Spriano ◽  
Eugenio Gaudio ◽  
Chiara Tarantelli ◽  
Luciano Cascione ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
The Novel ◽  
Deacetylase Inhibitor

scholarly journals The novel histone deacetylase inhibitor thailandepsin A inhibits anaplastic thyroid cancer growth

2014 ◽  
Vol 190 (1) ◽  
pp. 191-197 ◽  
Author(s):  
Eric Weinlander ◽  
Yash Somnay ◽  
April D. Harrison ◽  
Cheng Wang ◽  
Yi-Qiang Cheng ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Anaplastic Thyroid Cancer ◽  
Cancer Growth ◽  
The Novel ◽  
Deacetylase Inhibitor

Reprogramming of neuroblastoma cells by the histone deacetylase inhibitor valproic acid

2004 ◽  
Vol 216 (03) ◽  
Author(s):  
H Deubzer ◽  
J Schulte ◽  
L Schweigerer ◽  
J Hoheisel ◽  
O Witt
Keyword(s):  
Valproic Acid ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Neuroblastoma Cells ◽  
Deacetylase Inhibitor

Regulation of cellular processes by PPARγ ligands in neuroblastoma cells is modulated by the level of retinoblastoma protein expression

2004 ◽  
Vol 32 (5) ◽  
pp. 840-842 ◽  
Author(s):  
V.C. Emmans ◽  
H.A. Rodway ◽  
A.N. Hunt ◽  
K.A. Lillycrop
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Trichostatin A ◽  
Neuroblastoma Cells ◽  
Retinoblastoma Protein ◽  
Peroxisome Proliferator ◽  
Peroxisome Proliferator Activated Receptor ◽  
Cellular Processes ◽  
Deacetylase Inhibitor

Neuroblastoma is a childhood cancer, which spontaneously regresses. This has led to a search for agents that mimic this process. We show that both natural and synthetic ligands of PPARγ (peroxisome-proliferator-activated receptor γ) inhibit the growth of neuroblastoma cells in vitro. The degree of PPAR activation was attenuated however in the presence of the retinoblastoma protein. Addition of trichostatin A, a histone deacetylase inhibitor, abolished retinoblastoma protein repression of PPAR activity. Moreover, enhanced growth inhibition was observed when neuroblastoma cells were treated with a PPARγ ligand and a histone deacetylase inhibitor, suggesting a combination therapy to treat neuroblastoma might prove more effective than using either agent alone.

scholarly journals The Novel Histone Deacetylase Inhibitor, OBP-801, Induces Apoptosis in Rhabdoid Tumors by Releasing the Silencing of NOXA

2020 ◽  
Vol 19 (10) ◽  
pp. 1992-2000
Author(s):  
Yohei Sugimoto ◽  
Yoshiki Katsumi ◽  
Tomoko Iehara ◽  
Daisuke Kaneda ◽  
Chihiro Tomoyasu ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
The Novel ◽  
Deacetylase Inhibitor ◽  
Rhabdoid Tumors
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