Concomitant activation of adenylyl cyclase suppresses the opposite influences of CB1 cannabinoid receptor agonists on tyrosine hydroxylase expression

Biochemical Pharmacology ◽

10.1016/j.bcp.2008.10.010 ◽

2009 ◽

Vol 77 (2) ◽

pp. 216-227 ◽

Author(s):

Barbara Bosier ◽

Emmanuel Hermans ◽

Didier M. Lambert

Keyword(s):

Tyrosine Hydroxylase ◽

Adenylyl Cyclase ◽

Cannabinoid Receptor ◽

Receptor Agonists ◽

Cb1 Cannabinoid Receptor

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Design, synthesis, and structure–activity relationship study of conformationally constrained analogs of indole-3-carboxamides as novel CB1 cannabinoid receptor agonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2010.06.067 ◽

2010 ◽

Vol 20 (16) ◽

pp. 4918-4921 ◽

Author(s):

Takao Kiyoi ◽

Mark York ◽

Stuart Francis ◽

Darren Edwards ◽

Glenn Walker ◽

...

Keyword(s):

Cannabinoid Receptor ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Conformationally Constrained ◽

Receptor Agonists ◽

Cb1 Cannabinoid Receptor ◽

Structure Activity ◽

Relationship Study

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Pyridoxine improves hippocampal cognitive function via increases of serotonin turnover and tyrosine hydroxylase, and its association with CB1 cannabinoid receptor-interacting protein and the CB1 cannabinoid receptor pathway

Biochimica et Biophysica Acta (BBA) - General Subjects ◽

10.1016/j.bbagen.2017.09.006 ◽

2017 ◽

Vol 1861 (12) ◽

pp. 3142-3153 ◽

Author(s):

Hyo Young Jung ◽

Dae Won Kim ◽

Sung Min Nam ◽

Jong Whi Kim ◽

Jin Young Chung ◽

...

Keyword(s):

Cognitive Function ◽

Tyrosine Hydroxylase ◽

Cannabinoid Receptor ◽

Interacting Protein ◽

Cb1 Cannabinoid Receptor ◽

Serotonin Turnover

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The effect of multiple simulation parameters on MM/PBSA performance for binding affinity prediction of CB1 cannabinoid receptor agonists and antagonists

Chemical Biology & Drug Design ◽

10.1111/cbdd.13733 ◽

2020 ◽

Vol 96 (5) ◽

pp. 1244-1254 ◽

Author(s):

Jason S. E. Loo ◽

Amelia Y. Y. Yong ◽

Yen Nee Yong

Keyword(s):

Binding Affinity ◽

Cannabinoid Receptor ◽

Binding Affinity Prediction ◽

Affinity Prediction ◽

Receptor Agonists ◽

Cb1 Cannabinoid Receptor ◽

Simulation Parameters ◽

Receptor Agonists And Antagonists

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CP47,497-C8 and JWH073, commonly found in ‘Spice’ herbal blends, are potent and efficacious CB1 cannabinoid receptor agonists

European Journal of Pharmacology ◽

10.1016/j.ejphar.2011.01.066 ◽

2011 ◽

Vol 659 (2-3) ◽

pp. 139-145 ◽

Author(s):

Brady K. Atwood ◽

Donghoon Lee ◽

Alex Straiker ◽

Theodore S. Widlanski ◽

Ken Mackie

Keyword(s):

Cannabinoid Receptor ◽

Receptor Agonists ◽

Cb1 Cannabinoid Receptor

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Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression

Best Practice & Research Clinical Endocrinology & Metabolism ◽

10.1016/j.beem.2008.09.003 ◽

2009 ◽

Vol 23 (1) ◽

pp. 133-144 ◽

Author(s):

Fabrício A. Moreira ◽

Maximilian Grieb ◽

Beat Lutz

Keyword(s):

Side Effects ◽

Cannabinoid Receptor ◽

Anxiety And Depression ◽

Receptor Agonists ◽

Cb1 Cannabinoid Receptor ◽

Receptor Agonists And Antagonists

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CB1 cannabinoid receptor agonists increase intracranial self-stimulation thresholds in the rat

Psychopharmacology ◽

10.1007/s00213-004-2050-0 ◽

2004 ◽

Vol 179 (2) ◽

pp. 498-508 ◽

Author(s):

Styliani Vlachou ◽

George G. Nomikos ◽

George Panagis

Keyword(s):

Cannabinoid Receptor ◽

Receptor Agonists ◽

Cb1 Cannabinoid Receptor ◽

Self Stimulation

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Falcarinol (Panaxynol) is a CB1 cannabinoid receptor antagonist and induces pro-allergic effects in skin

Planta Medica ◽

10.1055/s-0029-1234271 ◽

2009 ◽

Vol 75 (09) ◽

Author(s):

J Gertsch ◽

M Leonti ◽

L Casu ◽

F Cottiglia ◽

S Raduner ◽

...

Keyword(s):

Receptor Antagonist ◽

Cannabinoid Receptor ◽

Cb1 Cannabinoid Receptor

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Faculty Opinions recommendation of Induction of CB1 cannabinoid receptor by inflammation in primary afferent neurons facilitates antihyperalgesic effect of peripheral CB1 agonist.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047910.497933 ◽

2006 ◽

Author(s):

Gyongyi Horvath

Keyword(s):

Cannabinoid Receptor ◽

Afferent Neurons ◽

Primary Afferent Neurons ◽

Primary Afferent ◽

Cb1 Cannabinoid Receptor

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Faculty Opinions recommendation of An essential role for constitutive endocytosis, but not activity, in the axonal targeting of the CB1 cannabinoid receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1085831.538757 ◽

2007 ◽

Author(s):

Joël Bockaert

Keyword(s):

Essential Role ◽

Cannabinoid Receptor ◽

Cb1 Cannabinoid Receptor ◽

Axonal Targeting

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Faculty Opinions recommendation of CB1 cannabinoid receptor antagonism: a new strategy for the treatment of liver fibrosis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14551.472055 ◽

2006 ◽

Author(s):

Fabio Marra

Keyword(s):

Liver Fibrosis ◽

Cannabinoid Receptor ◽

Receptor Antagonism ◽

Cb1 Cannabinoid Receptor ◽

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