ATP synthase, an essential enzyme in growth and multiplication is modulated by protein tyrosine phosphatase in Mycobacterium tuberculosis H37Ra

Atp Synthase ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Essential Enzyme

Faculty Opinions recommendation of Structural basis for selective inhibition of Mycobacterium tuberculosis protein tyrosine phosphatase PtpB.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1095045.550033 ◽

2007 ◽

Author(s):

Celerino Abad-Zapatero

Keyword(s):

Tyrosine Phosphatase ◽

Selective Inhibition ◽

Structural Basis ◽

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1109201108 ◽

2011 ◽

Vol 108 (48) ◽

pp. 19371-19376 ◽

Cited By ~ 199

Author(s):

D. Wong ◽

H. Bach ◽

J. Sun ◽

Z. Hmama ◽

Y. Av-Gay

Keyword(s):

Tyrosine Phosphatase ◽

Sydowiols A–C: Mycobacterium tuberculosis protein tyrosine phosphatase inhibitors from an East China Sea marine-derived fungus, Aspergillus sydowii

Tetrahedron Letters ◽

10.1016/j.tetlet.2013.08.137 ◽

2013 ◽

Vol 54 (45) ◽

pp. 6081-6083 ◽

Cited By ~ 20

Author(s):

Xinru Liu ◽

Fuhang Song ◽

Li Ma ◽

Caixia Chen ◽

Xue Xiao ◽

...

Keyword(s):

East China Sea ◽

Tyrosine Phosphatase ◽

East China ◽

Aspergillus Sydowii ◽

Phosphatase Inhibitors ◽

Protein Tyrosine ◽

China Sea

Compound Molecular Logic in Accessing the Active Site of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B

Journal of the American Chemical Society ◽

10.1021/jacs.8b08070 ◽

2018 ◽

Vol 140 (44) ◽

pp. 14747-14752

Author(s):

Thomas E. Morrell ◽

Ilona U. Rafalska-Metcalf ◽

Haw Yang ◽

Jhih-Wei Chu

Keyword(s):

Active Site ◽

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Molecular Logic

Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products

PLoS ONE ◽

10.1371/journal.pone.0077081 ◽

2013 ◽

Vol 8 (10) ◽

pp. e77081 ◽

Cited By ~ 30

Author(s):

Alessandra Mascarello ◽

Mattia Mori ◽

Louise Domeneghini Chiaradia-Delatorre ◽

Angela Camila Orbem Menegatti ◽

Franco Delle Monache ◽

...

Keyword(s):

Natural Products ◽

Tyrosine Phosphatase ◽

Discovery of Mycobacterium Tuberculosis Protein Tyrosine Phosphatase A (MptpA) Inhibitors Based on Natural Products and a Fragment-Based Approach

ChemBioChem ◽

10.1002/cbic.200500171 ◽

2005 ◽

Vol 6 (10) ◽

pp. 1749-1753 ◽

Cited By ~ 47

Author(s):

Michael Manger ◽

Michael Scheck ◽

Heino Prinz ◽

Jens Peter von Kries ◽

Thomas Langer ◽

...

Keyword(s):

Natural Products ◽

Tyrosine Phosphatase ◽

Docking- and pharmacophore-based virtual screening for the identification of novel Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitor with a thiobarbiturate scaffold

Bioorganic Chemistry ◽

10.1016/j.bioorg.2018.12.038 ◽

2019 ◽

Vol 85 ◽

pp. 229-239 ◽

Cited By ~ 1

Author(s):

Dongfeng Zhang ◽

Yun Lin ◽

Xi Chen ◽

Wenting Zhao ◽

Dongni Chen ◽

...

Keyword(s):

Virtual Screening ◽

Tyrosine Phosphatase ◽

Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2019.04.034 ◽

2019 ◽

Vol 29 (13) ◽

pp. 1665-1672 ◽

Cited By ~ 2

Author(s):

Alex Washburn ◽

Sanofar Abdeen ◽

Yulia Ovechkina ◽

Anne-Marie Ray ◽

Mckayla Stevens ◽

...

Keyword(s):

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

Dual Targeting

Highly Potent and Selective N-Aryl Oxamic Acid-Based Inhibitors for Mycobacterium tuberculosis Protein Tyrosine Phosphatase B

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.0c00302 ◽

2020 ◽

Vol 63 (17) ◽

pp. 9212-9227

Author(s):

Kasi Viswanatharaju Ruddraraju ◽

Devesh Aggarwal ◽

Congwei Niu ◽

Erica Anne Baker ◽

Ruo-yu Zhang ◽

...

Keyword(s):

Tyrosine Phosphatase ◽

Synthetic thiosemicarbazones as a new class of Mycobacterium tuberculosis protein tyrosine phosphatase A inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2018.10.030 ◽

2018 ◽

Vol 26 (21) ◽

pp. 5742-5750 ◽

Cited By ~ 7

Author(s):

Larissa Sens ◽

Ana Caroline Arruda de Souza ◽

Lucas Antonio Pacheco ◽

Angela Camila Orbem Menegatti ◽

Mattia Mori ◽

...

Keyword(s):

Tyrosine Phosphatase ◽

Protein Tyrosine ◽

New Class