Highly sensitive photoelectrochemical assay for DNA methyltransferase activity and inhibitor screening by exciton energy transfer coupled with enzyme cleavage biosensing strategy

2015 ◽  
Vol 64 ◽  
pp. 449-455 ◽  
Author(s):  
Qingming Shen ◽  
Li Han ◽  
Gaochao Fan ◽  
E.S. Abdel-Halim ◽  
Liping Jiang ◽  
...  
Keyword(s):  
Energy Transfer ◽  
Dna Methyltransferase ◽  
Exciton Energy ◽  
Methyltransferase Activity ◽  
Inhibitor Screening ◽  
Highly Sensitive ◽  
Enzyme Cleavage ◽  
Photoelectrochemical Assay

Highly sensitive methyltransferase activity assay and inhibitor screening based on fluorescence quenching of graphene oxide integrated with the site-specific cleavage of restriction endonuclease

2014 ◽  
Vol 50 (73) ◽  
pp. 10691-10694 ◽  
Author(s):  
Lijuan Ji ◽  
Zhewei Cai ◽  
Yingdan Qian ◽  
Ping Wu ◽  
Hui Zhang ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Fluorescence Quenching ◽  
Restriction Endonuclease ◽  
Dna Methyltransferase ◽  
Activity Assay ◽  
Methyltransferase Activity ◽  
Site Specific ◽  
Inhibitor Screening ◽  
Selective Approach ◽  
Highly Sensitive

A sensitive and selective approach for the DNA methyltransferase activity assay and MTase inhibitor screening is reported.

Viral cDNA-based extension for highly sensitive fluorescence detection of DNA methyltransferase activity

2018 ◽  
Vol 255 ◽  
pp. 3488-3494 ◽  
Author(s):  
Ying Wang ◽  
Binxiao Li ◽  
Ningbo Zhang ◽  
Dongmei Xi ◽  
Jing Liu ◽  
...  
Keyword(s):  
Fluorescence Detection ◽  
Dna Methyltransferase ◽  
Methyltransferase Activity ◽  
Highly Sensitive ◽  
Viral Cdna
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