Intraspecific variation of meroditerpenoids in the brown alga Stypopodium zonale guiding the isolation of new compounds

Two new steroids, (20S)-3β,20-dihydroxyergosta-5,24(28)-dien-16-one (7) and 3β-hydroxyergosta-5,24(28)-dien-16-one (9), and two new diastereoisomeric meroditerpenes, compounds (10) and (11), † have been isolated from the brown alga Cystophora brownii (Cystoseiraceae). Their structures were elucidated by one- and two-dimensional n.m.r. and other spectrometric and chemical methods.

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Pharmacological properties of a marine natural product, stypoldione, obtained from the brown alga Stypopodium zonale

Hydrobiologia ◽

10.1007/bf00027652 ◽

1984 ◽

Vol 116-117 (1) ◽

pp. 141-145 ◽

Cited By ~ 14

Author(s):

E. Timothy O'Brien ◽

Steven White ◽

Robert S. Jacobs ◽

George B. Boder ◽

Leslie Wilson

Keyword(s):

Natural Product ◽

Brown Alga ◽

Marine Natural Product ◽

Pharmacological Properties ◽

Stypopodium Zonale

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Terpenoids From the Brown Alga Cystophora moniliformis

Australian Journal of Chemistry ◽

10.1071/ch9880049 ◽

1988 ◽

Vol 41 (1) ◽

pp. 49 ◽

Cited By ~ 11

Author(s):

IA Vanaltena

Keyword(s):

Brown Alga ◽

Major Metabolite ◽

New Compounds

The alga Cystophora moniliformis contains two new bisnorsesquiterpenes, (5E,9E)-5,6-epoxy-6,10,14-trimethylpentadeca-9,13-dien-2-one (3) and its cyclized derivative (4), and the (2E) and (2Z) isomers of geranylgeranal epoxide, (5) and (6), respectively. The structures of the new compounds were deduced by spectroscopic means. Geranylacetone (1) was the major metabolite present in the alga.

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Diterpenoid Hydroperoxides from the Far-Eastern Brown Alga Dictyota dichotoma

Australian Journal of Chemistry ◽

10.1071/ch08343 ◽

2009 ◽

Vol 62 (9) ◽

pp. 1185 ◽

Cited By ~ 8

Author(s):

Sophia A. Kolesnikova ◽

Ekaterina G. Lyakhova ◽

Anatoly I. Kalinovsky ◽

Pavel S. Dmitrenok ◽

Sergei A. Dyshlovoy ◽

...

Keyword(s):

Cell Lines ◽

Brown Alga ◽

Human Cancer ◽

Algal Species ◽

Human Cancer Cell ◽

Dictyota Dichotoma ◽

Human Cancer Cell Lines ◽

New Compounds ◽

Far Eastern ◽

First Time

Two new compounds, dictyohydroperoxide 1 and hydroperoxyacetoxycrenulide 2, (Scheme 1) containing hydroperoxyl groups rarely found in algal terpenoids were isolated from the Russian population of brown alga Dictyota dichotoma. The known compounds acetoxycrenulide 4 and squalene were also found in this algal species for the first time. Some of the isolated compounds showed moderate cytoxicity against human cancer cell lines.

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