Synthesis and structure–activity relationship of 6-arylureido-3-pyrrol-2-ylmethylideneindolin-2-one derivatives as potent receptor tyrosine kinase inhibitors

Kinase Inhibitors ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of ◽

Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: Synthesis and structure–activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.02.025 ◽

2006 ◽

Vol 16 (10) ◽

pp. 2672-2676 ◽

Cited By ~ 20

Author(s):

Laurent F.A. Hennequin ◽

Peter Ballard ◽

F. Tom Boyle ◽

Bénédicte Delouvrié ◽

Rebecca P.A. Ellston ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Egf Receptor ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of ◽

Orally Active ◽

Novel 4-Anilinoquinazolines with C-7 Basic Side Chains: Design and Structure Activity Relationship of a Series of Potent, Orally Active, VEGF Receptor Tyrosine Kinase Inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm011022e ◽

2002 ◽

Vol 45 (6) ◽

pp. 1300-1312 ◽

Cited By ~ 205

Author(s):

Laurent F. Hennequin ◽

Elaine S. E. Stokes ◽

Andrew P. Thomas ◽

Craig Johnstone ◽

Patrick A. Plé ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Activity Relationship ◽

Vegf Receptor ◽

Structure Activity ◽

Relationship Of ◽

Orally Active ◽

Design and Structure−Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors

Journal of Medicinal Chemistry ◽

10.1021/jm990345w ◽

1999 ◽

Vol 42 (26) ◽

pp. 5369-5389 ◽

Cited By ~ 161

Author(s):

Laurent F. Hennequin ◽

Andrew P. Thomas ◽

Craig Johnstone ◽

Elaine S. E. Stokes ◽

Patrick A. Plé ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Activity Relationship ◽

Vegf Receptor ◽

New Class ◽

Structure Activity ◽

Relationship Of ◽

ChemInform Abstract: Design and Structure-Activity Relationship of a New Class of Potent VEGF Receptor Tyrosine Kinase Inhibitors.

ChemInform ◽

10.1002/chin.200013120 ◽

2010 ◽

Vol 31 (13) ◽

pp. no-no

Author(s):

Laurent F. Hennequin ◽

et al. et al.

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Activity Relationship ◽

Vegf Receptor ◽

New Class ◽

Structure Activity ◽

Relationship Of ◽

Novel 4-Anilinoquinazolines with C-6 Carbon-Linked Side Chains: Synthesis and Structure—Activity Relationship of a Series of Potent, Orally Active, EGF Receptor Tyrosine Kinase Inhibitors.

ChemInform ◽

10.1002/chin.200634220 ◽

2006 ◽

Vol 37 (34) ◽

Author(s):

Laurent F. A. Hennequin ◽

et al. et al.

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Egf Receptor ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of ◽

Orally Active ◽

Structure–activity relationship study of EphB3 receptor tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.09.010 ◽

2009 ◽

Vol 19 (21) ◽

pp. 6122-6126 ◽

Cited By ~ 17

Author(s):

Lixin Qiao ◽

Sungwoon Choi ◽

April Case ◽

Thomas G. Gainer ◽

Kathleen Seyb ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study ◽

Structure-activity relationship of 7-aryl-2-anilino-pyrrolopyrimidines as Mer and Axl tyrosine kinase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry ◽

10.1080/14756366.2020.1825407 ◽

2020 ◽

Vol 35 (1) ◽

pp. 1822-1833

Author(s):

Shin Hyuck Chung ◽

Jiwon Park ◽

Jung Wuk Lee ◽

Jiho Song ◽

Danbee Jung ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Activity Relationship ◽

Structure Activity ◽

Structure-Activity Relationship of 4,6-Disubstituted Pyrimidines as EGFR and VEGFR-2 Tyrosine Kinase Inhibitors

Bulletin of the Korean Chemical Society ◽

10.1002/bkcs.11278 ◽

2017 ◽

Vol 38 (11) ◽

pp. 1255-1256 ◽

Cited By ~ 2

Author(s):

Jiho Song ◽

Jung Wook Lee ◽

Shin Hyuck Chung ◽

Michelle A. Wenas ◽

Kyung Hoon Min

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Activity Relationship ◽

Structure Activity ◽

Structure–Activity Relationship of Halophenols as a New Class of Protein Tyrosine Kinase Inhibitors

International Journal of Molecular Sciences ◽

10.3390/ijms12096104 ◽

2011 ◽

Vol 12 (9) ◽

pp. 6104-6115 ◽

Cited By ~ 4

Author(s):

Xiu E Feng ◽

Wan Yi Zhao ◽

Shu Rong Ban ◽

Cheng Xiao Zhao ◽

Qing Shan Li ◽

...

Keyword(s):

Tyrosine Kinase ◽

Protein Tyrosine Kinase ◽

Kinase Inhibitors ◽

Activity Relationship ◽

Protein Tyrosine ◽

New Class ◽

Structure Activity ◽

Synthesis and structure–activity relationship of 4-(2-aryl-cyclopropylamino)-quinoline-3-carbonitriles as EGFR tyrosine kinase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2007.07.071 ◽

2007 ◽

Vol 17 (21) ◽

pp. 5978-5982 ◽

Cited By ~ 30

Author(s):

Madhavi Pannala ◽

Sunil Kher ◽

Norma Wilson ◽

John Gaudette ◽

Ila Sircar ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitors ◽

Activity Relationship ◽

Egfr Tyrosine Kinase ◽

Structure Activity ◽

Egfr Tyrosine Kinase Inhibitors ◽