Design, synthesis, and structure activity relationship (SAR) studies of novel imidazo[1,2-a] pyridine derivatives as Nek2 inhibitors

Activity Relationship ◽

Pyridine Derivatives ◽

Design Synthesis ◽

Sar Studies ◽

Design, synthesis and structure–activity relationship (SAR) studies of imidazo[4,5-b]pyridine derived purine isosteres and their potential as cytotoxic agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.10.037 ◽

2015 ◽

Vol 89 ◽

pp. 21-31 ◽

Cited By ~ 26

Author(s):

Ayyiliath M. Sajith ◽

K.K. Abdul Khader ◽

Nithin Joshi ◽

Manchala Nageswar Reddy ◽

M. Syed Ali Padusha ◽

...

Keyword(s):

Cytotoxic Agents ◽

Activity Relationship ◽

Design Synthesis ◽

Sar Studies ◽

Design, synthesis and structure–activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: Dual activity as cholinesterase and Aβ-aggregation inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2011.02.030 ◽

2011 ◽

Vol 19 (7) ◽

pp. 2269-2281 ◽

Cited By ~ 25

Author(s):

Tarek Mohamed ◽

Xiaobei Zhao ◽

Lila K. Habib ◽

Jerry Yang ◽

Praveen P.N. Rao

Keyword(s):

Activity Relationship ◽

Pyrimidine Derivatives ◽

Design Synthesis ◽

Sar Studies ◽

Structure Activity ◽

Aβ Aggregation ◽

Aggregation Inhibitors

Design, Synthesis, Bioactivity, and Structure−Activity Relationship (SAR) Studies of Novel Benzoylphenylureas Containing Oxime Ether Group

Journal of Agricultural and Food Chemistry ◽

10.1021/jf801901h ◽

2008 ◽

Vol 56 (23) ◽

pp. 11376-11391 ◽

Cited By ~ 39

Author(s):

Ranfeng Sun ◽

Maoyun Lü ◽

Li Chen ◽

Qingshan Li ◽

Haibin Song ◽

...

Keyword(s):

Activity Relationship ◽

Oxime Ether ◽

Ether Group ◽

Design Synthesis ◽

Sar Studies ◽

Design, Synthesis, and Structure−Activity Relationship Studies of Novel 1-[(1-Acyl-4-piperidyl)methyl]-1H-2-methylimidazo[4,5-c]pyridine Derivatives as Potent, Orally Active Platelet−Activating Factor Antagonists

Journal of Medicinal Chemistry ◽

10.1021/jm950555i ◽

1996 ◽

Vol 39 (2) ◽

pp. 487-493 ◽

Cited By ~ 15

Author(s):

Elena Carceller ◽

Manuel Merlos ◽

Marta Giral ◽

Dolors Balsa ◽

Julián García-Rafanell ◽

...

Keyword(s):

Platelet Activating Factor ◽

Activity Relationship ◽

Pyridine Derivatives ◽

Design Synthesis ◽

Structure Activity ◽

Orally Active

ChemInform Abstract: Design, Synthesis, and Structure-Activity Relationship Studies of Novel 1-((1-Acyl-4-piperidyl)methyl)-1H-2-methylimidazo(4,5-c)pyridine Derivatives as Potent, Orally Active Platelet-Activating Factor (PAF) Antagonists.

ChemInform ◽

10.1002/chin.199619166 ◽

2010 ◽

Vol 27 (19) ◽

pp. no-no

Author(s):

E. CARCELLER ◽

M. MERLOS ◽

M. GIRAL ◽

D. BALSA ◽

J. GARCIA-RAFANELL ◽

...

Keyword(s):

Platelet Activating Factor ◽

Activity Relationship ◽

Pyridine Derivatives ◽

Design Synthesis ◽

Structure Activity ◽

Paf Antagonists ◽

Orally Active

Structure Activity Relationship of Arylidene Pyrrolo and Pyrido [2,1-b] Quinazolones as Cytotoxic Agents: Synthesis, SAR Studies, Biological Evaluation and Docking Studies

Medicinal Chemistry ◽

10.2174/1573406411309050003 ◽

2013 ◽

Vol 9 (5) ◽

pp. 642-650 ◽

Cited By ~ 3

Author(s):

Veenu Mangla ◽

Kunal Nepali ◽

Gagandip Singh ◽

Jagjeet Singh ◽

Santosh Guru ◽

...

Keyword(s):

Docking Studies ◽

Biological Evaluation ◽

Cytotoxic Agents ◽

Activity Relationship ◽

Sar Studies ◽

Structure Activity ◽

Relationship Of

Design, Synthesis and Structure-Activity Relationship Studies of Novel 4 (1-adamantyl) Phenyl Analogues as HIF-1α Inhibitors

Medicinal Chemistry ◽

10.2174/1573406412666151109113007 ◽

2016 ◽

Vol 12 (4) ◽

pp. 338-346 ◽

Cited By ~ 2

Author(s):

Yan Xia ◽

Qiong Duan ◽

Bao-Hua Zhao ◽

Dong-Feng Li ◽

Rui-Bin Hou

Keyword(s):

Activity Relationship ◽

Design Synthesis ◽

Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113291 ◽

2021 ◽

pp. 113291

Author(s):

Peng Li ◽

Ying Liu ◽

Hua Yang ◽

Hong-Min Liu

Keyword(s):

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

New substituted pyrazolones and dipyrazolotriazines as promising tyrosyl-tRNA synthetase and peroxiredoxin-5 inhibitors: Design, synthesis, molecular docking and structure-activity relationship (SAR) analysis

Bioorganic Chemistry ◽

10.1016/j.bioorg.2021.104704 ◽

2021 ◽

Vol 109 ◽

pp. 104704

Author(s):

Ismail M.M. Othman ◽

Mohamed A.M. Gad-Elkareem ◽

El Hassane Anouar ◽

Kaïss Aouadi ◽

Mejdi Snoussi ◽

...

Keyword(s):

Molecular Docking ◽

Trna Synthetase ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Sar Analysis

Antileishmanial Chalcones: Statistical Design, Synthesis, and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

Journal of Medicinal Chemistry ◽

10.1021/jm980410m ◽

1998 ◽

Vol 41 (24) ◽

pp. 4819-4832 ◽

Cited By ~ 183

Author(s):

Simon Feldbæk Nielsen ◽

Søren Brøgger Christensen ◽

Gabriele Cruciani ◽

Arsalan Kharazmi ◽

Tommy Liljefors

Keyword(s):

Three Dimensional ◽

Statistical Design ◽

Quantitative Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Relationship Analysis ◽