Design, synthesis, kinetic, molecular dynamics, and hypoglycemic effect characterization of new and potential selective benzimidazole derivatives as Protein Tyrosine Phosphatase 1B inhibitors

2021 ◽  
pp. 116418
Author(s):  
Mara Ibeth Campos-Almazán ◽  
Miguel Flores-Ramos ◽  
Alicia Hernández-Campos ◽  
Rafael Castillo ◽  
Erick Sierra-Campos ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Hypoglycemic Effect ◽  
Benzimidazole Derivatives ◽  
Protein Tyrosine Phosphatase 1B ◽  
Design Synthesis ◽  
Protein Tyrosine

Characterization of active compounds from Gracilaria lemaneiformis inhibiting the protein tyrosine phosphatase 1B activity

2017 ◽  
Vol 8 (9) ◽  
pp. 3271-3275 ◽  
Author(s):  
Xinfeng Guo ◽  
Dongyu Gu ◽  
Miao Wang ◽  
Yu Huang ◽  
Haoquan Li ◽  
...  
Keyword(s):  
Protein Tyrosine Phosphatase ◽  
Tyrosine Phosphatase ◽  
Gracilaria Lemaneiformis ◽  
Protein Tyrosine Phosphatase 1B ◽  
Active Compounds ◽  
Protein Tyrosine

Gracilaria lemaneiformis, an edible alga, with various bioactivities is a traditional dish and a favorite food.

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