An efficient, asymmetric solid-phase synthesis of benzothiadiazine-substituted tetramic acids: Potent inhibitors of the hepatitis C virus RNA-dependent RNA polymerase

2006 ◽  
Vol 16 (8) ◽  
pp. 2205-2208 ◽  
Author(s):  
Karen A. Evans ◽  
Deping Chai ◽  
Todd L. Graybill ◽  
George Burton ◽  
Robert T. Sarisky ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Rna Polymerase ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Hepatitis C Virus Rna ◽  
Rna Dependent Rna Polymerase ◽  
Phase Synthesis ◽  
Virus Rna ◽  
Tetramic Acids

A homogeneous, solid-phase assay for hepatitis C virus RNA-dependent RNA polymerase

2006 ◽  
Vol 359 (1) ◽  
pp. 106-111 ◽  
Author(s):  
Ying-Kai Wang ◽  
Karen L. Rigat ◽  
Susan B. Roberts ◽  
Min Gao
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Rna Polymerase ◽  
Solid Phase ◽  
Hepatitis C Virus Rna ◽  
Rna Dependent Rna Polymerase ◽  
Virus Rna ◽  
Solid Phase Assay

B-ring modified aurones as promising allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase

2014 ◽  
Vol 80 ◽  
pp. 579-592 ◽  
Author(s):  
Amel Meguellati ◽  
Abdelhakim Ahmed-Belkacem ◽  
Wei Yi ◽  
Romain Haudecoeur ◽  
Marie Crouillère ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Rna Polymerase ◽  
Hepatitis C Virus Rna ◽  
Allosteric Inhibitors ◽  
Rna Dependent Rna Polymerase ◽  
Virus Rna

Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase

Virology ◽  
2019 ◽  
Vol 529 ◽  
pp. 226-233 ◽  
Author(s):  
Ryosuke Suzuki ◽  
Mami Matsuda ◽  
Takashi Shimoike ◽  
Koichi Watashi ◽  
Hideki Aizaki ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Protein Kinase ◽  
Rna Polymerase ◽  
Protein Kinase R ◽  
Hepatitis C Virus Rna ◽  
Rna Dependent Rna Polymerase ◽  
Virus Rna
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